Silencing of Long Noncoding RNA Nespas Aggravates Microglial Cell Death and Neuroinflammation in Ischemic Stroke

Elevated microRNA-129-5p level ameliorates neuroinflammation and blood-spinal cord barrier damage after ischemia-reperfusion by inhibiting HMGB1 and the TLR3-cytokine pathway

(2017) Xiao-Qian Li et al.   Journal of Neuroinflammation

Homocysteine exaggerates microglia activation and neuroinflammation through microglia localized STAT3 overactivation following ischemic stroke

(2017) Shuang Chen et al.   Journal of Neuroinflammation

The Ubiquitin E3 Ligase TRAF6 Exacerbates Ischemic Stroke by Ubiquitinating and Activating Rac1

(2017) Tao Li et al.   JOURNAL OF NEUROSCIENCE

Long Noncoding RNA Malat1 Regulates Cerebrovascular Pathologies in Ischemic Stroke

(2017) Xuejing Zhang et al.   JOURNAL OF NEUROSCIENCE

Isosteviol Sodium Protects Against Permanent Cerebral Ischemia Injury in Mice via Inhibition of NF-κB–Mediated Inflammatory and Apoptotic Responses

(2017) Hao Zhang et al.   Journal of Stroke & Cerebrovascular Diseases

Pathogenic mechanisms following ischemic stroke

(2017) Seyed Esmaeil Khoshnam et al.   NEUROLOGICAL SCIENCES

Sirtuin 6 protects the brain from cerebral ischemia/reperfusion injury through NRF2 activation

(2017) Wei Zhang et al.   NEUROSCIENCE

Long Noncoding RNA H19 Promotes Neuroinflammation in Ischemic Stroke by Driving Histone Deacetylase 1–Dependent M1 Microglial Polarization

(2017) Jue Wang et al.   STROKE

LncRNA TINCR attenuates cardiac hypertrophy by epigenetically silencing CaMKII

(2017) Mingjing Shao et al.   Oncotarget

Isosteviol Sodium Protects Against Permanent Cerebral Ischemia Injury in Mice via Inhibition of NF-κB–Mediated Inflammatory and Apoptotic Responses

(2017) Hao Zhang et al.   Journal of Stroke & Cerebrovascular Diseases

The lncRNA, Nespas, Is Associated with Osteoarthritis Progression and Serves as a Potential New Prognostic Biomarker

(2017) Sujung Park et al.   Cartilage

Tripartite Motif 8 (TRIM8) Positively Regulates Pro-inflammatory Responses in Pseudomonas aeruginosa-Induced Keratitis Through Promoting K63-Linked Polyubiquitination of TAK1 Protein

(2016) Litao Guo et al.   INFLAMMATION

LRP1 modulates the microglial immune response via regulation of JNK and NF-κB signaling pathways

(2016) Longyu Yang et al.   Journal of Neuroinflammation

The Sur1-Trpm4 channel regulates NOS2 transcription in TLR4-activated microglia

(2016) David B. Kurland et al.   Journal of Neuroinflammation

Long Noncoding RNA FosDT Promotes Ischemic Brain Injury by Interacting with REST-Associated Chromatin-Modifying Proteins

(2015) S. L. Mehta et al.   JOURNAL OF NEUROSCIENCE

Noggin improves ischemic brain tissue repair and promotes alternative activation of microglia in mice

(2014) Jin A. Shin et al.   BRAIN BEHAVIOR AND IMMUNITY

CX3CR1 deficiency suppresses activation and neurotoxicity of microglia/macrophage in experimental ischemic stroke

(2014) Zhiwei Tang et al.   Journal of Neuroinflammation

Cross-talk between the inflammatory response, sympathetic activation and pulmonary infection in the ischemic stroke

(2014) Pawel J Winklewski et al.   Journal of Neuroinflammation

Long non-coding RNAs: A new frontier in the study of human diseases

(2013) Xuefei Shi et al.   CANCER LETTERS

RNA in the Loop

(2013) Johnny T.Y. Kung et al.   DEVELOPMENTAL CELL

TAK1 inhibition for treatment of cerebral ischemia

(2012) Dirk A. Ridder et al.   EXPERIMENTAL NEUROLOGY

Tripartite motif 8 (TRIM8) modulates TNF - and IL-1 -triggered NF- B activation by targeting TAK1 for K63-linked polyubiquitination

(2011) Q. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TAK1 Lys-158 but not Lys-209 is required for IL-1β-induced Lys63-linked TAK1 polyubiquitination and IKK/NF-κB activation

(2010) Yihui Fan et al.   CELLULAR SIGNALLING

Transcribed dark matter: meaning or myth?

(2010) C. P. Ponting et al.   HUMAN MOLECULAR GENETICS

Lysine 63-linked Polyubiquitination of TAK1 at Lysine 158 Is Required for Tumor Necrosis Factor α- and Interleukin-1β-induced IKK/NF-κB and JNK/AP-1 Activation

(2009) Yihui Fan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The role of inflammation in CNS injury and disease

(2006) Sian-Marie Lucas et al.   BRITISH JOURNAL OF PHARMACOLOGY