Direct Nucleus‐Targeted Drug Delivery Using Cascade pH e /Photo Dual‐Sensitive Polymeric Nanocarrier for Cancer Therapy

Reversible Shielding between Dual Ligands for Enhanced Tumor Accumulation of ZnPc-Loaded Micelles

(2019) Jing Cao et al.   NANO LETTERS

Ultrasound and Redox-Triggered Morphology Transitions of Supramolecular Self-Assemblies with pH Responsiveness for Triple-Controlled Release

(2019) Hao Yao et al.   LANGMUIR

Activatable Semiconducting Theranostics: Simultaneous Generation and Ratiometric Photoacoustic Imaging of Reactive Oxygen Species In Vivo

(2018) Zhen Yang et al.   ADVANCED MATERIALS

Photoinduced PEG deshielding from ROS-sensitive linkage-bridged block copolymer-based nanocarriers for on-demand drug delivery

(2018) Jie Li et al.   BIOMATERIALS

Development of a Light-Controlled Nanoplatform for Direct Nuclear Delivery of Molecular and Nanoscale Materials

(2018) Ya-Xuan Zhu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Methodologies to investigate intracellular barriers for nucleic acid delivery in non-viral gene therapy

(2018) Lotte M.P. Vermeulen et al.   Nano Today

CRISPR–Cas9 genome editing induces a p53-mediated DNA damage response

(2018) Emma Haapaniemi et al.   NATURE MEDICINE

Cancer Cell-Derived, Drug-Loaded Nanovesicles Induced by Sulfhydryl-Blocking for Effective and Safe Cancer Therapy

(2018) Dominique Ingato et al.   ACS Nano

Binary Cooperative Prodrug Nanoparticles Improve Immunotherapy by Synergistically Modulating Immune Tumor Microenvironment

(2018) Bing Feng et al.   ADVANCED MATERIALS

Tumor-Vasculature-on-a-Chip for Investigating Nanoparticle Extravasation and Tumor Accumulation

(2018) Hao-Fei Wang et al.   ACS Nano

Core–Satellite Nanomedicines for in Vivo Real-Time Monitoring of Enzyme-Activatable Drug Release by Fluorescence and Photoacoustic Dual-Modal Imaging

(2018) Xianlei Li et al.   ACS Nano

Tumor Acidity/NIR Controlled Interaction of Transformable Nanoparticle with Biological Systems for Cancer Therapy

(2017) Dongdong Li et al.   NANO LETTERS

Acidity-triggered TAT-presenting nanocarriers augment tumor retention and nuclear translocation of drugs

(2017) Wei Jiang et al.   Nano Research

Targeting genomic rearrangements in tumor cells through Cas9-mediated insertion of a suicide gene

(2017) Zhang-Hui Chen et al.   NATURE BIOTECHNOLOGY

Hierarchical Targeting Strategy for Enhanced Tumor Tissue Accumulation/Retention and Cellular Internalization

(2016) Sheng Wang et al.   ADVANCED MATERIALS

Overcoming tumor resistance to cisplatin by cationic lipid-assisted prodrug nanoparticles

(2016) Zhi-Ting Cao et al.   BIOMATERIALS

Tumor acidity-sensitive linkage-bridged block copolymer for therapeutic siRNA delivery

(2016) Cong-Fei Xu et al.   BIOMATERIALS

Host–guest binding motifs based on hyperbranched polymers

(2016) Quanbing Mou et al.   CHEMICAL COMMUNICATIONS

Co-delivery of erlotinib and doxorubicin by pH-sensitive charge conversion nanocarrier for synergistic therapy

(2016) Yongju He et al.   JOURNAL OF CONTROLLED RELEASE

How successful is nuclear targeting by nanocarriers?

(2016) Salma N. Tammam et al.   JOURNAL OF CONTROLLED RELEASE

pH- and NIR Light-Responsive Micelles with Hyperthermia-Triggered Tumor Penetration and Cytoplasm Drug Release to Reverse Doxorubicin Resistance in Breast Cancer

(2015) Haijun Yu et al.   ADVANCED FUNCTIONAL MATERIALS

Chiral recognition of l-tryptophan with beta-cyclodextrin-modified biomimetic single nanochannel

(2015) Ganhua Xie et al.   CHEMICAL COMMUNICATIONS

Tumor Acidity-Sensitive Polymeric Vector for Active Targeted siRNA Delivery

(2015) Chun-Yang Sun et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Functional Supramolecular Polymers for Biomedical Applications

(2014) Ruijiao Dong et al.   ADVANCED MATERIALS

Heteromultivalent ligand-decoration for actively targeted nanomedicine

(2014) Christa L. Modery-Pawlowski et al.   BIOMATERIALS

Nucleus-Targeted Drug Delivery: Theoretical Optimization of Nanoparticles Decoration for Enhanced Intracellular Active Transport

(2014) Ohad Cohen et al.   NANO LETTERS

Curb challenges of the “Trojan Horse” approach: Smart strategies in achieving effective yet safe cell-penetrating peptide-based drug delivery

(2013) Yongzhuo Huang et al.   ADVANCED DRUG DELIVERY REVIEWS

Intact Doxil is taken up intracellularly and released doxorubicin sequesters in the lysosome: Evaluated by in vitro / in vivo live cell imaging

(2013) Ann L.B. Seynhaeve et al.   JOURNAL OF CONTROLLED RELEASE

Endosomolytic Anionic Polymer for the Cytoplasmic Delivery of siRNAs in Localized In Vivo Applications

(2012) Sariah Khormaee et al.   ADVANCED FUNCTIONAL MATERIALS

A Highly Emissive Conjugated Polyelectrolyte Vector for Gene Delivery and Transfection

(2012) Xuli Feng et al.   ADVANCED MATERIALS

Nuclear-Targeted Drug Delivery of TAT Peptide-Conjugated Monodisperse Mesoporous Silica Nanoparticles

(2012) Limin Pan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Intracellular pathways and nuclear localization signal peptide-mediated gene transfection by cationic polymeric nanovectors

(2011) Qinglian Hu et al.   BIOMATERIALS

Nuclear drug delivery for cancer chemotherapy

(2011) Meihua Sui et al.   JOURNAL OF CONTROLLED RELEASE

Cancer-Cell-Specific Induction of Apoptosis Using Mesoporous Silica Nanoparticles as Drug-Delivery Vectors

(2010) Jessica M. Rosenholm et al.   Small

Covalently Combining Carbon Nanotubes with Anticancer Agent: Preparation and Antitumor Activity

(2009) Wei Wu et al.   ACS Nano

Active targeting schemes for nanoparticle systems in cancer therapeutics

(2008) James D. Byrne et al.   ADVANCED DRUG DELIVERY REVIEWS