Dihydroartemisinin regulates the immune system by promotion of CD8+ T lymphocytes and suppression of B cell responses

Dihydroartemisinin treatment exhibits antitumor effects in glioma cells through induction of apoptosis

(2017) Chun-Hua Xu et al.   Molecular Medicine Reports

From ancient herb to modern drug: Artemisia annua and artemisinin for cancer therapy

(2017) Thomas Efferth   SEMINARS IN CANCER BIOLOGY

Dihydroartemisinin induces apoptosis in human gastric cancer cell line BGC-823 through activation of JNK1/2 and p38 MAPK signaling pathways

(2016) Shuyi Zhang et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Toxoplasma gondii Infection Promotes Neuroinflammation Through Cytokine Networks and Induced Hyperalgesia in BALB/c Mice

(2015) Hossein Mahmoudvand et al.   INFLAMMATION

Dihydroartemisinin inhibits activation of the Toll-like receptor 4 signaling pathway and production of type I interferon in spleen cells from lupus-prone MRL/lpr mice

(2014) Xueqin Huang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Artesunate Abolishes Germinal Center B Cells and Inhibits Autoimmune Arthritis

(2014) Lifei Hou et al.   PLoS One

Initiation of apoptosis, cell cycle arrest and autophagy of esophageal cancer cells by dihydroartemisinin

(2013) Xiao-Xue Du et al.   BIOMEDICINE & PHARMACOTHERAPY

Evaluation of the immunosuppressive activity of artesunate in vitro and in vivo

(2013) Tan Li et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Artemisinin Analogue SM934 Ameliorates Murine Experimental Autoimmune Encephalomyelitis through Enhancing the Expansion and Functions of Regulatory T Cell

(2013) Xin Li et al.   PLoS One

Anti-cancer activity of DHA on gastric cancer—an in vitro and in vivo study

(2013) Haijun Sun et al.   TUMOR BIOLOGY

Qinghaosu (artemisinin): Chemistry and pharmacology

(2012) Ying Li   ACTA PHARMACOLOGICA SINICA

Dihydroartemisinin Ameliorates Inflammatory Disease by Its Reciprocal Effects on Th and Regulatory T Cell Function via Modulating the Mammalian Target of Rapamycin Pathway

(2012) Yan G. Zhao et al.   JOURNAL OF IMMUNOLOGY

Allicin enhances host pro-inflammatory immune responses and protects against acute murine malaria infection

(2012) Yonghui Feng et al.   MALARIA JOURNAL

Oral administration of artemisinin analog SM934 ameliorates lupus syndromes in MRL/lpr mice by inhibiting Th1 and Th17 cell responses

(2011) Li-Fei Hou et al.   ARTHRITIS AND RHEUMATISM

Immunology of Toxoplasma gondii

(2011) Melba Munoz et al.   IMMUNOLOGICAL REVIEWS

The CD8 T-cell road to immunotherapy of toxoplasmosis

(2011) Rajarshi Bhadra et al.   Immunotherapy

Anti-inflammatory and immunomodulatory mechanisms of artemisinin on contact hypersensitivity

(2011) Tan Li et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Heterogeneous and Tissue-Specific Regulation of Effector T Cell Responses by IFN-  during Plasmodium berghei ANKA Infection

(2011) A. Villegas-Mendez et al.   JOURNAL OF IMMUNOLOGY

Systemic Lupus Erythematosus

(2011) George C. Tsokos   NEW ENGLAND JOURNAL OF MEDICINE

Anti-Malarial Drug Artesunate Attenuates Experimental Allergic Asthma via Inhibition of the Phosphoinositide 3-Kinase/Akt Pathway

(2011) Chang Cheng et al.   PLoS One

Control of Toxoplasma reactivation by rescue of dysfunctional CD8+ T-cell response via PD-1-PDL-1 blockade

(2011) R. Bhadra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Artemisinin activity against Plasmodium falciparum requires hemoglobin uptake and digestion

(2011) N. Klonis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Redundant and Pathogenic Roles for IL-22 in Mycobacterial, Protozoan, and Helminth Infections

(2010) M. S. Wilson et al.   JOURNAL OF IMMUNOLOGY

Artemisone and Artemiside Control Acute and Reactivated Toxoplasmosis in a Murine Model

(2009) I. R. Dunay et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

DoesToxoplasma gondiiInfection Affect the Levels of IgE and Cytokines (IL-5, IL-6, IL-10, IL-12, and TNF-alpha)?

(2009) Joanna Matowicka-Karna et al.   Clinical & Developmental Immunology

Modulation of p38 MAPK Activity in Regulatory T Cells after Tolerance with Anti-DNA Ig Peptide in (NZB x NZW)F1 Lupus Mice

(2009) E. V. Lourenco et al.   JOURNAL OF IMMUNOLOGY

The anti-malaria agent artesunate inhibits expression of vascular endothelial growth factor and hypoxia-inducible factor-1α in human rheumatoid arthritis fibroblast-like synoviocyte

(2009) Ya He et al.   RHEUMATOLOGY INTERNATIONAL

IL-6–dependent spontaneous proliferation is required for the induction of colitogenic IL-17–producing CD8+T cells

(2008) Masaki Tajima et al.   JOURNAL OF EXPERIMENTAL MEDICINE