Galactosyl and sialyl clusters: synthesis and evaluation against T. cruzi parasite

Meet Our Editorial Board Member

(2018) Werner Sieghart   CURRENT MEDICINAL CHEMISTRY

Treatment of adult chronic indeterminate Chagas disease with benznidazole and three E1224 dosing regimens: a proof-of-concept, randomised, placebo-controlled trial

(2018) Faustino Torrico et al.   LANCET INFECTIOUS DISEASES

Cluster glycosides and heteroglycoclusters presented in alternative arrangements

(2018) Andreza S. Figueredo et al.   TETRAHEDRON LETTERS

An in vitro and in vivo evaluation of new potential trans -sialidase inhibitors of Trypanosoma cruzi predicted by a computational drug repositioning method

(2017) Edgar E. Lara-Ramirez et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Phenotypic screening approaches for Chagas disease drug discovery

(2017) Eric Chatelain et al.   Expert Opinion on Drug Discovery

Anti-trypanosomatid drug discovery: an ongoing challenge and a continuing need

(2017) Mark C. Field et al.   NATURE REVIEWS MICROBIOLOGY

The Trypanosoma cruzi Surface, a Nanoscale Patchwork Quilt

(2017) Juan Mucci et al.   TRENDS IN PARASITOLOGY

An Updated Synthesis of the Diazo-Transfer Reagent Imidazole-1-sulfonyl Azide Hydrogen Sulfate

(2016) Garrett T. Potter et al.   JOURNAL OF ORGANIC CHEMISTRY

Trypanosoma cruzi Invasion into Host Cells: A Complex Molecular Targets Interplay

(2016) Vanessa Leiria Campo et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Thetrans-sialidase, the majorTrypanosoma cruzivirulence factor: Three decades of studies

(2015) L Freire-de-Lima et al.   GLYCOBIOLOGY

Emerging trends in enzyme inhibition by multivalent nanoconstructs

(2015) Nasreddine Kanfar et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Click chemistry oligomerisation of azido-alkyne-functionalised galactose accesses triazole-linked linear oligomers and macrocycles that inhibit Trypanosoma cruzi macrophage invasion

(2015) Vanessa L. Campo et al.   TETRAHEDRON

Antibodies against Mucin-Based Glycopeptides AffectTrypanosoma cruziCell Invasion and Tumor Cell Viability

(2014) Vanessa L. Campo et al.   CHEMBIOCHEM

Glyconanoparticles for the plasmonic detection and discrimination between human and avian influenza virus

(2013) María J. Marín et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Recent Researches in Triazole Compounds as Medicinal Drugs

(2012) C. -H. Zhou et al.   CURRENT MEDICINAL CHEMISTRY

Design, synthesis and the effect of 1,2,3-triazole sialylmimetic neoglycoconjugates on Trypanosoma cruzi and its cell surface trans-sialidase

(2011) Vanessa L. Campo et al.   BIOORGANIC & MEDICINAL CHEMISTRY

‘Click chemistry’ synthesis of a library of 1,2,3-triazole-substituted galactose derivatives and their evaluation against Trypanosoma cruzi and its cell surface trans-sialidase

(2010) Ivone Carvalho et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Calixarene and Calixresorcarene Glycosides: Their Synthesis and Biological Applications

(2010) Alessandro Dondoni et al.   CHEMICAL REVIEWS

Biomedical applications of dendrimers: a tutorial

(2010) Meredith A. Mintzer et al.   CHEMICAL SOCIETY REVIEWS