Gene-based analysis in HRC imputed genome wide association data identifies three novel genes for Alzheimer’s disease

POLARIS: Polygenic LD-adjusted risk score approach for set-based analysis of GWAS data

(2018) Emily Baker et al.   GENETIC EPIDEMIOLOGY

ZNF423: A New Player in Estrogen Receptor-Positive Breast Cancer

(2018) Heather M. Bond et al.   Frontiers in Endocrinology

Identification of potential target genes of ROR-alpha in THP1 and HUVEC cell lines

(2017) Cagri Gulec et al.   EXPERIMENTAL CELL RESEARCH

Retinoic acid-related orphan receptor alpha (RORA) variants are associated with autism spectrum disorder

(2017) Arezou Sayad et al.   METABOLIC BRAIN DISEASE

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

(2017) Rebecca Sims et al.   NATURE GENETICS

RORα controls hepatic lipid homeostasis via negative regulation of PPARγ transcriptional network

(2017) Kyeongkyu Kim et al.   Nature Communications

Ribosomal transcription is regulated by PGC-1alpha and disturbed in Huntington’s disease

(2017) Sarah Jesse et al.   Scientific Reports

Analyzing the genes related to Alzheimer’s disease via a network and pathway-based approach

(2017) Yan-Shi Hu et al.   Alzheimers Research & Therapy

Neurodegeneration and the Circadian Clock

(2017) Suzanne Hood et al.   Frontiers in Aging Neuroscience

Next-generation genotype imputation service and methods

(2016) Sayantan Das et al.   NATURE GENETICS

PPARγ-coactivator-1α gene transfer reduces neuronal loss and amyloid-β generation by reducing β-secretase in an Alzheimer’s disease model

(2016) Loukia Katsouri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polycomb dysregulation in gliomagenesis targets a Zfp423-dependent differentiation network

(2016) Elena Signaroldi et al.   Nature Communications

Convergent genetic and expression data implicate immunity in Alzheimer's disease

(2015) Lesley Jones et al.   Alzheimers & Dementia

The hitchhiker’s guide to PGC-1α isoform structure and biological functions

(2015) Vicente Martínez-Redondo et al.   DIABETOLOGIA

Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

(2015)   NATURE NEUROSCIENCE

Gene-Wide Analysis Detects Two New Susceptibility Genes for Alzheimer's Disease

(2014) Valentina Escott-Price et al.   PLoS One

Restored Immunosuppressive Effect of Mesenchymal Stem Cells on B Cells After Olfactory 1/Early B Cell Factor-Associated Zinc-Finger Protein Down-Regulation in Patients With Systemic Lupus Erythematosus

(2014) Xuebing Feng et al.   Arthritis & Rheumatology

Astroglial PGC-1alpha increases mitochondrial antioxidant capacity and suppresses inflammation: implications for multiple sclerosis

(2014) Philip G Nijland et al.   Acta Neuropathologica Communications

The retinoid-related orphan receptor alpha (RORA) gene and fear-related psychopathology

(2013) Mark W. Miller et al.   JOURNAL OF AFFECTIVE DISORDERS

Aberrant ZNF423 impedes B cell differentiation and is linked to adverse outcome ofETV6-RUNX1negative B precursor acute lymphoblastic leukemia

(2013) Lena Harder et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

(2013) Jean-Charles Lambert et al.   NATURE GENETICS

ERK and p38 inhibitors attenuate memory deficits and increase CREB phosphorylation and PGC-1α levels in Aβ-injected rats

(2012) Ghorbangol Ashabi et al.   BEHAVIOURAL BRAIN RESEARCH

Exome Capture Reveals ZNF423 and CEP164 Mutations, Linking Renal Ciliopathies to DNA Damage Response Signaling

(2012) Moumita Chaki et al.   CELL

Annotation of functional variation in personal genomes using RegulomeDB

(2012) A. P. Boyle et al.   GENOME RESEARCH

GENCODE: The reference human genome annotation for The ENCODE Project

(2012) J. Harrow et al.   GENOME RESEARCH

A greatly extended PPARGC1A genomic locus encodes several new brain-specific isoforms and influences Huntington disease age of onset†

(2012) Selma M. Soyal et al.   HUMAN MOLECULAR GENETICS

Exome sequencing and the genetic basis of complex traits

(2012) Adam Kiezun et al.   NATURE GENETICS

TREM2 Variants in Alzheimer's Disease

(2012) Rita Guerreiro et al.   NEW ENGLAND JOURNAL OF MEDICINE

Transcriptional integration of mitochondrial biogenesis

(2012) Richard C. Scarpulla et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Regulation of PGC-1α, a nodal regulator of mitochondrial biogenesis

(2011) Pablo J Fernandez-Marcos et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

GATES: A Rapid and Powerful Gene-Based Association Test Using Extended Simes Procedure

(2011) Miao-Xin Li et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Quality control parameters on a large dataset of regionally dissected human control brains for whole genome expression studies

(2011) Daniah Trabzuni et al.   JOURNAL OF NEUROCHEMISTRY

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

(2011) Adam C Naj et al.   NATURE GENETICS

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

(2011) Paul Hollingworth et al.   NATURE GENETICS

Control of Gene Expression by the Retinoic Acid-Related Orphan Receptor Alpha in HepG2 Human Hepatoma Cells

(2011) Caroline Chauvet et al.   PLoS One

PGC-1α at the intersection of bioenergetics regulation and neuron function: From Huntington's disease to Parkinson's disease and beyond

(2011) Taiji Tsunemi et al.   PROGRESS IN NEUROBIOLOGY

Genome-wide Analysis of Genetic Loci Associated With Alzheimer Disease

(2010) Sudha Seshadri   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Genetic Evidence Implicates the Immune System and Cholesterol Metabolism in the Aetiology of Alzheimer's Disease

(2010) Lesley Jones et al.   PLoS One

Gene Ontology Analysis of GWA Study Data Sets Provides Insights into the Biology of Bipolar Disorder

(2009) Peter Holmans et al.   AMERICAN JOURNAL OF HUMAN GENETICS

ZNF423 Is Critically Required for Retinoic Acid-Induced Differentiation and Is a Marker of Neuroblastoma Outcome

(2009) Sidong Huang et al.   CANCER CELL

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

(2009) Denise Harold et al.   NATURE GENETICS

Efficacy of PPAR-γ agonist pioglitazone in mild Alzheimer disease

(2009) Tomohiko Sato et al.   NEUROBIOLOGY OF AGING

The nuclear receptor RORα exerts a bi-directional regulation of IL-6 in resting and reactive astrocytes

(2009) Nathalie Journiac et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA