Ambrosin, a potent NF-κβ inhibitor, ameliorates lipopolysaccharide induced memory impairment, comparison to curcumin

Phytochemicals as inhibitors of NF-κB for treatment of Alzheimer’s disease

(2018) Ean-Jeong Seo et al.   PHARMACOLOGICAL RESEARCH

Protective role of chrysin on thioacetamide-induced hepatic encephalopathy in rats

(2018) Salma A. El-Marasy et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Curcumin in Alzheimer’s disease: Can we think to new strategies and perspectives for this molecule?

(2017) Melania Maria Serafini et al.   PHARMACOLOGICAL RESEARCH

Inhibition of TNF-α-Induced Inflammation by Sesquiterpene Lactones from Saussurea lappa and Semi-Synthetic Analogues

(2017) Siwattra Choodej et al.   PLANTA MEDICA

Involvement of insulin resistance in D-galactose-induced age-related dementia in rats: Protective role of metformin and saxagliptin

(2017) Sara Kenawy et al.   PLoS One

Anti-cancer stem cell activity of a sesquiterpene lactone isolated from Ambrosia arborescens and of a synthetic derivative

(2017) Wendy Soria Sotillo et al.   PLoS One

SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules

(2017) Antoine Daina et al.   Scientific Reports

Crocin Attenuates Kindling Development and Associated Cognitive Impairments in Mice via Inhibiting Reactive Oxygen Species-Mediated NF-κB Activation

(2016) Arindam Ghosh Mazumder et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

LPS-induced Murine Neuroinflammation Model: Main Features and Suitability for Pre-clinical Assessment of Nutraceuticals

(2016) Miryam Nava Catorce et al.   Current Neuropharmacology

Microglial immunophenotype in dementia with Alzheimer’s pathology

(2016) Thais Minett et al.   Journal of Neuroinflammation

Upstream regulators and downstream effectors of NF-κB in Alzheimer's disease

(2016) Zhe-Min Shi et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Novel promising therapeutics against chronic neuroinflammation and neurodegeneration in Alzheimer's disease

(2016) Madhuri Venigalla et al.   NEUROCHEMISTRY INTERNATIONAL

Examining the potential clinical value of curcumin in the prevention and diagnosis of Alzheimer’s disease

(2015) K. G. Goozee et al.   BRITISH JOURNAL OF NUTRITION

Reactive Oxygen Species, Redox Signaling and Neuroinflammation in Alzheimer's Disease: The NF-κB Connection

(2015) Upinder Kaur et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Inhibitory effect of sesquiterpene lactones and the sesquiterpene alcohol aromadendrane-4β,10α-diol on memory impairment in a mouse model of Alzheimer

(2015) Solomon K.S. Amoah et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Significance of NF-κB as a pivotal therapeutic target in the neurodegenerative pathologies of Alzheimer’s disease and multiple sclerosis

(2015) Mythily Srinivasan et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Systemic inflammation and microglial activation: systematic review of animal experiments

(2015) Inge C.M. Hoogland et al.   Journal of Neuroinflammation

Neuroinflammation in Alzheimer's disease

(2015) Michael T Heneka et al.   LANCET NEUROLOGY

Integrated genomic approaches identify major pathways and upstream regulators in late onset Alzheimer’s disease

(2015) Xinzhong Li et al.   Scientific Reports

Plant polyphenols as inhibitors of NF-κB induced cytokine production—a potential anti-inflammatory treatment for Alzheimer's disease?

(2015) Niloo Karunaweera et al.   Frontiers in Molecular Neuroscience

Cytotoxicity of the Sesquiterpene Lactones Neoambrosin and Damsin from Ambrosia maritima Against Multidrug-Resistant Cancer Cells

(2015) Mohamed Saeed et al.   Frontiers in Pharmacology

Parthenolide: from plant shoots to cancer roots

(2013) Akram Ghantous et al.   DRUG DISCOVERY TODAY

Therapeutic Roles of Curcumin: Lessons Learned from Clinical Trials

(2012) Subash C. Gupta et al.   AAPS Journal

admetSAR: A Comprehensive Source and Free Tool for Assessment of Chemical ADMET Properties

(2012) Feixiong Cheng et al.   Journal of Chemical Information and Modeling

Increased NF-κB signalling up-regulates BACE1 expression and its therapeutic potential in Alzheimer's disease

(2011) Chia-Hsiung Chen et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Blocking IL-1 Signaling Rescues Cognition, Attenuates Tau Pathology, and Restores Neuronal  -Catenin Pathway Function in an Alzheimer's Disease Model

(2011) M. Kitazawa et al.   JOURNAL OF IMMUNOLOGY

Morris Water Maze Test for Learning and Memory Deficits in Alzheimer's Disease Model Mice

(2011) Kelley Bromley-Brits et al.   Jove-Journal of Visualized Experiments

Identification of permeability-related hurdles in oral delivery of curcumin using the Caco-2 cell model

(2010) Banrida Wahlang et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer's disease

(2010) Marcello D'Amelio et al.   NATURE NEUROSCIENCE