High-resolution cryo-EM structures of the E. coli hemolysin ClyA oligomers

Cholesterol promotes Cytolysin A activity by stabilizing the intermediates during pore formation

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Structure and mechanism of the two-component α-helical pore-forming toxin YaxAB

(2018) Bastian Bräuning et al.   Nature Communications

Membrane insertion of α-xenorhabdolysin in near-atomic detail

(2018) Evelyn Schubert et al.   eLife

Cryo-EM structure of the gasdermin A3 membrane pore

(2018) Jianbin Ruan et al.   NATURE

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

Transmembrane oligomeric intermediates of pore forming toxin Cytolysin A determine leakage kinetics

(2017) Ayush Agrawal et al.   RSC Advances

The pesticidal Cry6Aa toxin from Bacillus thuringiensis is structurally similar to HlyE-family alpha pore-forming toxins

(2016) Alexey Dementiev et al.   BMC BIOLOGY

Structural Insights into the Niemann-Pick C1 (NPC1)-Mediated Cholesterol Transfer and Ebola Infection

(2016) Xin Gong et al.   CELL

Structural basis for the gating mechanism of the type 2 ryanodine receptor RyR2

(2016) Wei Peng et al.   SCIENCE

Accelerated cryo-EM structure determination with parallelisation using GPUs in RELION-2

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CTFFIND4: Fast and accurate defocus estimation from electron micrographs

(2015) Alexis Rohou et al.   JOURNAL OF STRUCTURAL BIOLOGY

Pore-forming toxins: ancient, but never really out of fashion

(2015) Matteo Dal Peraro et al.   NATURE REVIEWS MICROBIOLOGY

Structural basis for self-assembly of a cytolytic pore lined by protein and lipid

(2015) Koji Tanaka et al.   Nature Communications

The assembly dynamics of the cytolytic pore toxin ClyA

(2015) Stephan Benke et al.   Nature Communications

Structure of the Yeast Mitochondrial Large Ribosomal Subunit

(2014) A. Amunts et al.   SCIENCE

Molecular basis of transmembrane beta-barrel formation of staphylococcal pore-forming toxins

(2014) Daichi Yamashita et al.   Nature Communications

A Non-classical Assembly Pathway ofEscherichia coliPore-forming Toxin Cytolysin A

(2013) Monifa Fahie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of the NheA Component of the Nhe Toxin from Bacillus cereus: Implications for Function

(2013) Magdah Ganash et al.   PLoS One

Vibrio effector protein, VopQ, forms a lysosomal gated channel that disrupts host ion homeostasis and autophagic flux

(2013) A. Sreelatha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cryo-EM model validation using independent map reconstructions

(2013) Frank DiMaio et al.   PROTEIN SCIENCE

Collaboration gets the most out of software

(2013) Andrew Morin et al.   eLife

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

(2012) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

Crystal structure of the octameric pore of staphylococcal  -hemolysin reveals the  -barrel pore formation mechanism by two components

(2011) K. Yamashita et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structure and assembly of pore-forming proteins

(2010) Ioan Iacovache et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Identification and characterization of a type III secretion-associated chaperone in the type III secretion system 1 ofVibrio parahaemolyticus

(2009) Yukihiro Akeda et al.   FEMS MICROBIOLOGY LETTERS

The structure of a cytolytic α-helical toxin pore reveals its assembly mechanism

(2009) Marcus Mueller et al.   NATURE

The formation and structure of Escherichia coli K-12 haemolysin E pores

(2008) S. Hunt et al.   MICROBIOLOGY-SGM

X-ray crystal structure of the B component of Hemolysin BL fromBacillus cereus

(2008) Mahendra Madegowda et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS