BMP-2 gene delivery in cell-loaded and cell-free constructs for bone regeneration

How controlled release technology can aid gene delivery

(2015) Jun-Ichiro Jo et al.   Expert Opinion on Drug Delivery

Stromal cells and stem cells in clinical bone regeneration

(2015) Warren L. Grayson et al.   Nature Reviews Endocrinology

Gene therapy approaches to regenerating the musculoskeletal system

(2015) Christopher H. Evans et al.   Nature Reviews Rheumatology

Bone Morphogenetic Protein-2 Nonviral Gene Therapy in a Goat Iliac Crest Model for Bone Formation

(2015) Loek D. Loozen et al.   TISSUE ENGINEERING PART A

Effectiveness and Harms of Recombinant Human Bone Morphogenetic Protein-2 in Spine Fusion

(2013) Rongwei Fu et al.   ANNALS OF INTERNAL MEDICINE

Cochrane corner: bone morphogenetic protein (BMP) for fracture healing in adultsGarrisonKRShemiltIDonellS. Bone morphogenetic protein (BMP) for fracture healing in adults. Cochrane Database Systematic Reviews2010, Issue 6. Art. No.:CD006950. DOI: 10.1002/14651858

(2013) G. E. Glass et al.   Journal of Hand Surgery-European Volume

Sustained Release of BMP-2 in Bioprinted Alginate for Osteogenicity in Mice and Rats

(2013) Michelle T. Poldervaart et al.   PLoS One

Concise Review: Bridging the Gap: Bone Regeneration Using Skeletal Stem Cell-Based Strategies-Where Are We Now?

(2013) Jonathan I. Dawson et al.   STEM CELLS

Porous bioprinted constructs in BMP-2 non-viral gene therapy for bone tissue engineering

(2013) Loek D. Loozen et al.   Journal of Materials Chemistry B

Gene delivery to bone

(2012) C.H. Evans   ADVANCED DRUG DELIVERY REVIEWS

VEGF gene therapy: therapeutic angiogenesis in the clinic and beyond

(2012) M Giacca et al.   GENE THERAPY

Ischemia Is the Prime but Not the Only Cause of Human Multipotent Stromal Cell Death in Tissue-Engineered Constructs In Vivo

(2012) Pierre Becquart et al.   TISSUE ENGINEERING PART A

Use and efficacy of bone morphogenetic proteins in fracture healing

(2011) Suzanne N. Lissenberg-Thunnissen et al.   INTERNATIONAL ORTHOPAEDICS

“Same Day” Ex-vivo Regional Gene Therapy: A Novel Strategy to Enhance Bone Repair

(2011) Mandeep S Virk et al.   MOLECULAR THERAPY

Alginate: Properties and biomedical applications

(2011) Kuen Yong Lee et al.   PROGRESS IN POLYMER SCIENCE

Cell encapsulation using biopolymer gels for regenerative medicine

(2010) Nicola C. Hunt et al.   BIOTECHNOLOGY LETTERS

Osteoinduction by repeat plasmid injection of human bone morphogenetic protein-2

(2010) Kenji Osawa et al.   JOURNAL OF GENE MEDICINE

Human stem cell delivery for treatment of large segmental bone defects

(2010) Kenneth M. Dupont et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Luciferase Labeling for Multipotent Stromal Cell Tracking in Spinal Fusion Versus Ectopic Bone Tissue Engineering in Mice and Rats

(2010) Ruth E. Geuze et al.   TISSUE ENGINEERING PART A

Requirement for DNA CpG Content in TLR9-Dependent Dendritic Cell Activation Induced by DNA-Containing Immune Complexes

(2009) K. Yasuda et al.   JOURNAL OF IMMUNOLOGY

Stem Cells from Human Fat as Cellular Delivery Vehicles in an Athymic Rat Posterolateral Spine Fusion Model

(2008) Wellington K. Hsu et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

Design of Biodegradable Hydrogel for the Local and Sustained Delivery of Angiogenic Plasmid DNA

(2008) Hyun Joon Kong et al.   PHARMACEUTICAL RESEARCH

Nonvirally Engineered Porcine Adipose Tissue-Derived Stem Cells: Use in Posterior Spinal Fusion

(2008) Dima Sheyn et al.   STEM CELLS