Lettuce-derived secretory IgA specifically neutralizes the Shiga toxin 1 activity

Plant-derived secretory component forms secretory IgA with shiga toxin 1-specific dimeric IgA produced by mouse cells and whole plants

(2018) Katsuhiro Nakanishi et al.   PLANT CELL REPORTS

Expression and assembly of largest foreign protein in chloroplasts: oral delivery of human FVIII made in lettuce chloroplasts robustly suppresses inhibitor formation in haemophilia A mice

(2017) Kwang-Chul Kwon et al.   PLANT BIOTECHNOLOGY JOURNAL

Protection of Human Colon Cells from Shiga Toxin by Plant-based Recombinant Secretory IgA

(2017) Katsuhiro Nakanishi et al.   Scientific Reports

Tissue-specific circadian clocks in plants

(2016) Motomu Endo   CURRENT OPINION IN PLANT BIOLOGY

Biomanufacturing of protective antibodies and other therapeutics in edible plant tissues for oral applications

(2016) Paloma Juarez et al.   PLANT BIOTECHNOLOGY JOURNAL

Shiga Toxins as Multi-Functional Proteins: Induction of Host Cellular Stress Responses, Role in Pathogenesis and Therapeutic Applications

(2016) Moo-Seung Lee et al.   Toxins

Shiga toxins: from structure and mechanism to applications

(2015) Yau Sang Chan et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Low cost industrial production of coagulation factor IX bioencapsulated in lettuce cells for oral tolerance induction in hemophilia B

(2015) Jin Su et al.   BIOMATERIALS

Characterization of a plant-produced recombinant human secretory IgA with broad neutralizing activity against HIV

(2014) Matthew Paul et al.   mAbs

Production of Hybrid-IgG/IgA Plantibodies with Neutralizing Activity against Shiga Toxin 1

(2013) Katsuhiro Nakanishi et al.   PLoS One

Dietary choice affects Shiga toxin-producingEscherichia coli(STEC) O157:H7 colonization and disease

(2013) Steven D. Zumbrun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oral delivery of human biopharmaceuticals, autoantigens and vaccine antigens bioencapsulated in plant cells

(2012) Kwang-Chul Kwon et al.   ADVANCED DRUG DELIVERY REVIEWS

Human Plasma-derived Polymeric IgA and IgM Antibodies Associate with Secretory Component to Yield Biologically Active Secretory-like Antibodies

(2012) Stéphanie Longet et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ubiquitin promoter–terminator cassette promotes genetically stable expression of the taste-modifying protein miraculin in transgenic lettuce

(2011) Tadayoshi Hirai et al.   PLANT CELL REPORTS

Production of biologically active human thioredoxin 1 protein in lettuce chloroplasts

(2011) Soon Lim et al.   PLANT MOLECULAR BIOLOGY

Establishment of Recombinant Hybrid-IgG / IgA Immunoglobulin Specific for Shiga Toxin

(2011) Y. Tobisawa et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Shiga Toxin Interaction with Human Intestinal Epithelium

(2011) Stephanie Schüller   Toxins

Production of heterologous proteins in plants: Strategies for optimal expression

(2010) Priti N Desai et al.   BIOTECHNOLOGY ADVANCES

Induction of apoptosis by Shiga toxins

(2010) Vernon L Tesh   Future Microbiology

Intestinal damage in enterohemorrhagic Escherichia coli infection

(2010) Zivile D. Békássy et al.   PEDIATRIC NEPHROLOGY

Production of double repeated B subunit of Shiga toxin 2e at high levels in transgenic lettuce plants as vaccine material for porcine edema disease

(2010) Takeshi Matsui et al.   TRANSGENIC RESEARCH

Transgenic Lettuce Producing a Candidate Protein for Vaccine against Edema Disease

(2009) Takeshi MATSUI et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Shiga toxins — from cell biology to biomedical applications

(2009) Ludger Johannes et al.   NATURE REVIEWS MICROBIOLOGY

The intergenic region of Arabidopsis thaliana cab1 and cab2 divergent genes functions as a bidirectional promoter

(2009) Anish Mitra et al.   PLANTA

Characterization of Monoclonal Immunoglobulin A and G Against Shiga Toxin Binding Subunits Produced by Intranasal Immunization

(2008) T. Tanikawa et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY