Methods for Identifying Patients with Tropomyosin Receptor Kinase (TRK) Fusion Cancer
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Title
Methods for Identifying Patients with Tropomyosin Receptor Kinase (TRK) Fusion Cancer
Authors
Keywords
<em class="EmphasisTypeItalic ">NTRK</em> gene fusions, TRK fusions, TRK inhibitors, Next-generation sequencing, NGS
Journal
PATHOLOGY & ONCOLOGY RESEARCH
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-06-30
DOI
10.1007/s12253-019-00685-2
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Note: Only part of the references are listed.- Primary and Metastatic Melanoma With NTRK Fusions
- (2018) Cecilia Lezcano et al. AMERICAN JOURNAL OF SURGICAL PATHOLOGY
- NTRK Fusions Define a Novel Uterine Sarcoma Subtype With Features of Fibrosarcoma
- (2018) Sarah Chiang et al. AMERICAN JOURNAL OF SURGICAL PATHOLOGY
- A machine learning model to determine the accuracy of variant calls in capture-based next generation sequencing
- (2018) Jeroen van den Akker et al. BMC GENOMICS
- Emerging Targeted Therapy for Tumors with NTRK Fusion Proteins
- (2018) Ed S. Kheder et al. CLINICAL CANCER RESEARCH
- Insulin-like growth factor 1 receptor stabilizes the ETV6–NTRK3 chimeric oncoprotein by blocking its KPC1/Rnf123-mediated proteasomal degradation
- (2018) Cristina E. Tognon et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Development and Evaluation of a Pan-Sarcoma Fusion Gene Detection Assay Using the NanoString nCounter Platform
- (2018) Kenneth T.E. Chang et al. JOURNAL OF MOLECULAR DIAGNOSTICS
- Comparison of molecular testing modalities for detection of ROS1 rearrangements in a cohort of positive patient samples
- (2018) Kurtis D. Davies et al. Journal of Thoracic Oncology
- Larotrectinib for paediatric solid tumours harbouring NTRK gene fusions: phase 1 results from a multicentre, open-label, phase 1/2 study
- (2018) Theodore W Laetsch et al. LANCET ONCOLOGY
- Novel TLE4-NTRK2 fusion in a ganglioglioma identified by array-CGH and confirmed by NGS: Potential for a gene targeted therapy
- (2018) Nitya Prabhakaran et al. NEUROPATHOLOGY
- Efficacy of Larotrectinib in TRK Fusion–Positive Cancers in Adults and Children
- (2018) Alexander Drilon et al. NEW ENGLAND JOURNAL OF MEDICINE
- Integrative genomic profiling of large-cell neuroendocrine carcinomas reveals distinct subtypes of high-grade neuroendocrine lung tumors
- (2018) Julie George et al. Nature Communications
- Recurrent intragenic rearrangements of EGFR and BRAF in soft tissue tumors of infants
- (2018) Jenny Wegert et al. Nature Communications
- Entrectinib: an orally available, selective tyrosine kinase inhibitor for the treatment of NTRK, ROS1, and ALK fusion-positive solid tumors
- (2018) Dazhi Liu et al. Therapeutics and Clinical Risk Management
- Brief Report: Potent clinical and radiological response to larotrectinib in TRK fusion-driven high-grade glioma
- (2018) David S. Ziegler et al. BRITISH JOURNAL OF CANCER
- Cell-Free DNA Next-Generation Sequencing Prediction of Response and Resistance to Third-Generation EGFR Inhibitor
- (2018) Elena Helman et al. Clinical Lung Cancer
- Molecular characterization of cancers with NTRK gene fusions
- (2018) Zoran Gatalica et al. MODERN PATHOLOGY
- TRK Inhibition: A New Tumor-Agnostic Treatment Strategy
- (2018) Shivaani Kummar et al. Targeted Oncology
- Genetic landscape of papillary thyroid carcinoma in the Chinese population
- (2017) Jialong Liang et al. JOURNAL OF PATHOLOGY
- Activity of Entrectinib in a Patient With the First Reported NTRK Fusion in Neuroendocrine Cancer
- (2017) Darren Sigal et al. Journal of the National Comprehensive Cancer Network
- Recurrent EML4–NTRK3 fusions in infantile fibrosarcoma and congenital mesoblastic nephroma suggest a revised testing strategy
- (2017) Alanna J Church et al. MODERN PATHOLOGY
- Changing the Therapeutic Landscape in Non-small Cell Lung Cancers: the Evolution of Comprehensive Molecular Profiling Improves Access to Therapy
- (2017) Joshua K. Sabari et al. Current Oncology Reports
- Safety and Antitumor Activity of the Multitargeted Pan-TRK, ROS1, and ALK Inhibitor Entrectinib: Combined Results from Two Phase I Trials (ALKA-372-001 and STARTRK-1)
- (2017) Alexander Drilon et al. Cancer Discovery
- Clinical framework for next generation sequencing based analysis of treatment predictive mutations and multiplexed gene fusion detection in non-small cell lung cancer
- (2017) Kajsa Ericson Lindquist et al. Oncotarget
- Identification and characterization of a novel SCYL3-NTRK1 rearrangement in a colorectal cancer patient
- (2017) Massimo Milione et al. Oncotarget
- Detecting Gene Rearrangements in Patient Populations Through a 2-Step Diagnostic Test Comprised of Rapid IHC Enrichment Followed by Sensitive Next-Generation Sequencing
- (2017) Danielle A. Murphy et al. APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY
- Single-Center Experience with a Targeted Next Generation Sequencing Assay for Assessment of Relevant Somatic Alterations in Solid Tumors
- (2017) Aino Paasinen-Sohns et al. NEOPLASIA
- A Multiplexed Amplicon Approach for Detecting Gene Fusions by Next-Generation Sequencing
- (2016) Carol Beadling et al. JOURNAL OF MOLECULAR DIAGNOSTICS
- Transcriptome sequencing identifiesETV6-NTRK3as a gene fusion involved in GIST
- (2016) Monica Brenca et al. JOURNAL OF PATHOLOGY
- FGFR1 and NTRK3 actionable alterations in “Wild-Type” gastrointestinal stromal tumors
- (2016) Eileen Shi et al. Journal of Translational Medicine
- Congenital mesoblastic nephroma: a study of 19 cases using immunohistochemistry and ETV6-NTRK3 fusion gene rearrangement
- (2016) Dina El Demellawy et al. PATHOLOGY
- Testing for ROS1 in non-small cell lung cancer: a review with recommendations
- (2016) Lukas Bubendorf et al. VIRCHOWS ARCHIV
- Identifying fusion transcripts using next generation sequencing
- (2016) Shailesh Kumar et al. Wiley Interdisciplinary Reviews-RNA
- Precision medicine at Memorial Sloan Kettering Cancer Center: clinical next-generation sequencing enabling next-generation targeted therapy trials
- (2015) David M. Hyman et al. DRUG DISCOVERY TODAY
- INTEGRATE: gene fusion discovery using whole genome and transcriptome data
- (2015) Jin Zhang et al. GENOME RESEARCH
- Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT)
- (2015) Donavan T. Cheng et al. JOURNAL OF MOLECULAR DIAGNOSTICS
- Sensitivity to Entrectinib Associated With a Novel LMNA-NTRK1 Gene Fusion in Metastatic Colorectal Cancer
- (2015) Andrea Sartore-Bianchi et al. JNCI-Journal of the National Cancer Institute
- Durable Clinical Response to Entrectinib in NTRK1-Rearranged Non-Small Cell Lung Cancer
- (2015) Anna F. Farago et al. Journal of Thoracic Oncology
- An Oncogenic NTRK Fusion in a Patient with Soft-Tissue Sarcoma with Response to the Tropomyosin-Related Kinase Inhibitor LOXO-101
- (2015) R. C. Doebele et al. Cancer Discovery
- NTRK1 rearrangement in colorectal cancer patients: evidence for actionable target using patient-derived tumor cell line
- (2015) Su Jin Lee et al. Oncotarget
- Sensitivity to Entrectinib Associated With a Novel LMNA-NTRK1 Gene Fusion in Metastatic Colorectal Cancer
- (2015) Andrea Sartore-Bianchi et al. JNCI-Journal of the National Cancer Institute
- Targetable Kinase-Activating Lesions in Ph-like Acute Lymphoblastic Leukemia
- (2015) Kathryn G. Roberts et al. NEW ENGLAND JOURNAL OF MEDICINE
- ChildSeq-RNA
- (2014) Mohammed A. Qadir et al. JOURNAL OF MOLECULAR DIAGNOSTICS
- The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma
- (2014) Gang Wu et al. NATURE GENETICS
- Anchored multiplex PCR for targeted next-generation sequencing
- (2014) Zongli Zheng et al. NATURE MEDICINE
- The landscape and therapeutic relevance of cancer-associated transcript fusions
- (2014) K Yoshihara et al. ONCOGENE
- New Routes to Targeted Therapy of Intrahepatic Cholangiocarcinomas Revealed by Next-Generation Sequencing
- (2014) J. S. Ross et al. ONCOLOGIST
- NTRK1 Fusion in Glioblastoma Multiforme
- (2014) Jinkuk Kim et al. PLoS One
- The landscape of kinase fusions in cancer
- (2014) Nicolas Stransky et al. Nature Communications
- Kinase fusions are frequent in Spitz tumours and spitzoid melanomas
- (2014) Thomas Wiesner et al. Nature Communications
- TRKing Down an Old Oncogene in a New Era of Targeted Therapy
- (2014) Aria Vaishnavi et al. Cancer Discovery
- Mechanisms of Activation of Receptor Tyrosine Kinases: Monomers or Dimers
- (2014) Ichiro Maruyama Cells
- ETV6-NTRK3 is a common chromosomal rearrangement in radiation-associated thyroid cancer
- (2013) Rebecca J. Leeman-Neill et al. CANCER
- Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma
- (2013) David T W Jones et al. NATURE GENETICS
- Oncogenic and drug-sensitive NTRK1 rearrangements in lung cancer
- (2013) Aria Vaishnavi et al. NATURE MEDICINE
- Comparison of IHC, FISH and RT-PCR Methods for Detection of ALK Rearrangements in 312 Non-Small Cell Lung Cancer Patients in Taiwan
- (2013) Yi-Cheng Wu et al. PLoS One
- Mammary Analogue Secretory Carcinoma of the Salivary Glands With ETV6-NTRK3 Gene Fusion
- (2011) André Fehr et al. AMERICAN JOURNAL OF SURGICAL PATHOLOGY
- Tyrosine kinase gene fusions in cancer: translating mechanisms into targeted therapies
- (2011) Sandrine Medves et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Mammary Analogue Secretory Carcinoma of Salivary Glands, Containing the ETV6-NTRK3 Fusion Gene: A Hitherto Undescribed Salivary Gland Tumor Entity
- (2010) Alena Skálová et al. AMERICAN JOURNAL OF SURGICAL PATHOLOGY
- Transcriptome sequencing to detect gene fusions in cancer
- (2009) Christopher A. Maher et al. NATURE
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