Simvastatin Reduces Hepatic Oxidative Stress and Endoplasmic Reticulum Stress in Nonalcoholic Steatohepatitis Experimental Model

Activation of hepatic Nogo-B receptor expression—A new anti-liver steatosis mechanism of statins

(2018) Wenwen Zhang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Statins: An Under-Appreciated Asset for the Prevention and the Treatment of NAFLD or NASH and the Related Cardiovascular Risk

(2018) Vasilios G. Athyros et al.   Current Vascular Pharmacology

Liver Safety of Statins in Prediabetes or T2DM and Nonalcoholic Steatohepatitis: Post Hoc Analysis of a Randomized Trial

(2017) Fernando Bril et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Cause, Pathogenesis, and Treatment of Nonalcoholic Steatohepatitis

(2017) Anna M. Diehl et al.   NEW ENGLAND JOURNAL OF MEDICINE

Nonalcoholic Steatohepatitis is Associated with Cardiac Remodeling and Dysfunction

(2017) Tracey G. Simon et al.   Obesity

Metabolomic profiling distinction of human nonalcoholic fatty liver disease progression from a common rat model

(2017) JianHua Han et al.   Obesity

Current and emerging pharmacological therapy for non-alcoholic fatty liver disease

(2017) Ahad Eshraghian   WORLD JOURNAL OF GASTROENTEROLOGY

Underutilization of Statin Therapy Among Patients with NAFLD in the USA: Validation with Big Data

(2016) Haider Al Taii et al.   DIGESTIVE DISEASES AND SCIENCES

Low simvastatin concentrations reduce oleic acid-induced steatosis in HepG2 cells: An in vitro model of non-alcoholic fatty liver disease

(2016) MOHAMMAD J. ALKHATATBEH et al.   Experimental and Therapeutic Medicine

Statins Increase Mitochondrial and Peroxisomal Fatty Acid Oxidation in the Liver and Prevent Non-Alcoholic Steatohepatitis in Mice

(2016) Han-Sol Park et al.   Diabetes & Metabolism Journal

Statins Are Underutilized in Patients with Nonalcoholic Fatty Liver Disease and Dyslipidemia

(2015) Pierre Blais et al.   DIGESTIVE DISEASES AND SCIENCES

Acute atorvastatin is hepatoprotective against ischaemia-reperfusion injury in mice by modulating eNOS and microparticle formation

(2015) Hussam Ajamieh et al.   LIVER INTERNATIONAL

Obesity depresses the anti-inflammatory HSP70 pathway, contributing to NAFLD progression

(2014) Fábio Cangeri Di Naso et al.   Obesity

A gene variant ofPNPLA3, but not ofAPOC3, is associated with histological parameters of NAFLD in an obese population

(2013) A. Verrijken et al.   Obesity

Dietary modification dampens liver inflammation and fibrosis in obesity-related fatty liver disease

(2013) Claire Z. Larter et al.   Obesity

Simvastatin Ameliorates Liver Fibrosis via Mediating Nitric Oxide Synthase in Rats with Non-Alcoholic Steatohepatitis-Related Liver Fibrosis

(2013) Wei Wang et al.   PLoS One

Increased insulin receptor substrate 2 expression is associated with steatohepatitis and altered lipid metabolism in obese subjects

(2012) R Rametta et al.   INTERNATIONAL JOURNAL OF OBESITY

Atorvastatin protects obese mice against hepatic ischemia-reperfusion injury by Toll-like receptor-4 suppression and endothelial nitric oxide synthase activation

(2012) Hussam Ajamieh et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Quercetin Treatment Ameliorates Inflammation and Fibrosis in Mice with Nonalcoholic Steatohepatitis1–3

(2012) Eder Marcolin et al.   JOURNAL OF NUTRITION

Decreased nucleotide excision repair in steatotic livers associates with myeloperoxidase-immunoreactivity

(2011) Marten A. Schults et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Evolution of inflammation in nonalcoholic fatty liver disease: The multiple parallel hits hypothesis

(2010) Herbert Tilg et al.   HEPATOLOGY

Atorvastatin decreases serum levels of advanced glycation endproducts (AGEs) in nonalcoholic steatohepatitis (NASH) patients with dyslipidemia: clinical usefulness of AGEs as a biomarker for the attenuation of NASH

(2010) Yuki Kimura et al.   JOURNAL OF GASTROENTEROLOGY

Melatonin attenuates apoptotic liver damage in fulminant hepatic failure induced by the rabbit hemorrhagic disease virus

(2010) María J. Tuñón et al.   JOURNAL OF PINEAL RESEARCH

Deletion of nuclear factor-E2-related factor-2 leads to rapid onset and progression of nutritional steatohepatitis in mice

(2009) Hirokazu Sugimoto et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Liver NF-κB and AP-1 DNA Binding in Obese Patients

(2009) Luis A. Videla et al.   Obesity

Molecular Analysis of Endoplasmic Reticulum Stress Response After Global Forebrain Ischemia/Reperfusion in Rats: Effect of Neuroprotectant Simvastatin

(2008) P. Urban et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Investigating the potential neuroprotective effects of statins on DNA damage in mouse striatum

(2008) T.N. Coetsee et al.   FOOD AND CHEMICAL TOXICOLOGY

Simvastatin activates Keap1/Nrf2 signaling in rat liver

(2008) Ioannis G. Habeos et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

The Antioxidant Defense System Keap1-Nrf2 Comprises a Multiple Sensing Mechanism for Responding to a Wide Range of Chemical Compounds

(2008) M. Kobayashi et al.   MOLECULAR AND CELLULAR BIOLOGY