Article
Multidisciplinary Sciences
Kosuke Nakamura, Shinji Chiba, Takashi Kiuchi, Hiromi Nabeshi, Tomoaki Tsutsumi, Hiroshi Akiyama, Akiko Hachisuka
Summary: The Fukushima Daiichi nuclear power plant accident in Japan in 2011 caused contamination of foodstuffs with radionuclides. From 2012 to 2021, over 2.5 million food samples were examined in Japan, and 5,695 samples were found to exceed the Japanese maximum permitted levels for cesium-134 and cesium-137. However, the majority of foodstuffs have had low levels of radioactive contamination in recent years, except for certain difficult-to-manage food items.
Article
Environmental Sciences
Foster Miyanza, Thapelo Ramalepe, Mokgaetji Monyai, Eutilerio Chauque, Imasiku Nyambe, Luke Chimuka
Summary: The research focused on the risk assessment of heavy metals in common vegetables and fish sold in open markets in three towns of Zambia. The concentration of heavy metals varied across the towns, with cadmium (lowest) ranging from 1.9 to 662.7 mg/kg and aluminium (highest) ranging from 3.0 to 3472.3 mg/kg. Statistical analysis showed that the concentrations of samples from Kitwe and Lusaka were similar, while significant differences were observed between the samples from Kitwe and Kabwe, and Kabwe and Lusaka. The health risk analysis revealed potential non-carcinogenic and carcinogenic risks to consumers, with hazard index (HI) for all metals exceeding 1 and cancer risk (CR) for cadmium above 10(-4).
INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH
(2023)
Review
Chemistry, Applied
Junpeng Hu, Yanping Xian, Yuluan Wu, Rongqiao Chen, Hao Dong, Xiangchang Hou, Ming Liang, Bin Wang, Li Wang
Summary: Perchlorate, a contaminant found in water and food, can interfere with human health by affecting the thyroid gland. This review focuses on determining and removing perchlorate from water, discussing both analytical methods and removal techniques. The review provides insights into perchlorate occurrence and removal, highlighting the importance of reducing its harm to humans.
Article
Engineering, Environmental
Junning Ma, Yue Guan, Fuguo Xing, Evgeni Eltzov, Yan Wang, Xu Li, Bowen Tai
Summary: Mold contamination in foodstuffs causes economic losses and quality deterioration, therefore, non-destructive and accurate monitoring of mold occurrence is highly required. A whole-cell biosensor array was proposed to monitor pre-mold events in foodstuffs. The biosensor array showed high accuracy in discriminating healthy from moldy peanuts and maize, as well as pre-mold stages in infected peanuts and maize, demonstrating its potential in mold monitoring in foodstuffs.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Review
Food Science & Technology
Chuanqi Xie, Weidong Zhou
Summary: Traditional methods for detecting foodstuff hazards are time-consuming, inefficient, and destructive. Spectral imaging techniques, such as UV-Vis-NIR spectroscopy, THz spectroscopy, hyperspectral imaging, and Raman spectroscopy, have been proven to overcome these disadvantages. This study provides updated information on the advantages and disadvantages of these techniques, as well as the latest research on machine learning algorithms for detecting foodstuff hazards.
Article
Environmental Sciences
Elenka Georgieva, Vesela Yancheva, Stela Stoyanova, Iliana Velcheva, Ilia Iliev, Tonka Vasileva, Veselin Bivolarski, Eleonora Petkova, Brigitta Laszlo, Krisztian Nyeste, Laszlo Antal
Summary: This study investigated the short-term negative effects of chlorpyrifos and cypermethrin on common carp under laboratory conditions. Results showed that both pesticides impacted the biomarkers in common carp even at concentrations lower than those permitted by law, with cypermethrin showing higher toxicity compared to chlorpyrifos. Caution should be exercised when using these pesticides to avoid any risk.
Article
Agriculture, Dairy & Animal Science
E. Parand, J. W. Spek
Summary: In situ rumen incubation is used to estimate the rate of rumen microbial degradation of nutrients in feedstuffs, but accuracy may be compromised due to microbial contamination of in situ nitrogen residues. This study aimed to develop equations to predict microbial contamination of rumen incubation residues, with prediction models established based on a dataset from literature review. These models can improve the accuracy of predicting rumen protein degradation rate of feedstuffs and are essential for feed evaluation systems.
ANIMAL FEED SCIENCE AND TECHNOLOGY
(2021)
Article
Environmental Sciences
Muhammad Aamir Munir, Bushra Khan, Ishaq Ahmed Mian, Muhammad Rafiq, Samreen Shahzadi, Kashif Naeem, Iqbal Ahmad
Summary: Mercury bioaccumulation in fish and scalp hair was assessed in fishing communities along the river Swat in Pakistan. Significant differences were found in mercury concentrations between upstream and downstream fish and scalp hair. Health problems in the fishing community were attributed to mercury accumulation from fish consumption.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Agriculture, Multidisciplinary
Xin Wang, Wanyi Wang, Qingqing Zhu, Yawei Wang, Chunyang Liao, Guibin Jiang
Summary: This study investigated the levels of organophosphate esters (OPEs) in packaged and fresh foodstuffs in China, finding significantly higher concentrations of OPEs in packaged foods compared to fresh ones, and implicating food packaging materials as a potential source of OPE contamination in foods. Cereals were identified as the major contributor to dietary exposure to OPEs, with the overall exposure risk to OPEs via food intake considered low for the Chinese population.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Article
Environmental Sciences
Jayamini Bimali Koongolla, Lang Lin, Chang-Ping Yang, Yun-Feng Pan, Heng-Xiang Li, Shan Liu, Xiang-Rong Xu
Summary: In recent years, the widespread detection of microplastics in marine fish has raised concerns about potential risks to fish and human health. This study investigated the prevalence of microplastics in 271 marine fish collected from Beibu Gulf in the South China Sea. The results showed a microplastic occurrence rate of 93.7% and an average abundance of 1.02 items per individual. Different species, body sizes, living habitats, and feeding habits of marine fish exhibited significant variations in microplastic accumulation.
FRONTIERS IN MARINE SCIENCE
(2022)
Article
Biotechnology & Applied Microbiology
Hatice Imge Oktay Basegmez, Gozde Baydemir Pesint, Mustafa Nergiz, Okan Zenger
Summary: Ergosterol imprinted particles (Erg-MIPs) were synthesized for selective detection of ergosterol in mold samples, showing higher adsorption capacity compared to cholesterol and stigmasterol. They can be used for selective detection of ergosterol from food samples.
BIOTECHNOLOGY PROGRESS
(2021)
Article
Food Science & Technology
Kelvin Chou, Cheing-Tong Yan, Hsin- Hsiao
Summary: This study investigated postbaking mold contamination in a bakery company, revealing that baking and packaging gloves were the main source of contamination, and the slicing/packaging room had the highest air mold contamination. The data indicated the importance of comprehensive environmental monitoring for reducing mold occurrence and growth.
Article
Veterinary Sciences
Everton Andre de Oliveira, Yslla Fernanda Fitz Balo Merigueti, Isabella Braghin Ferreira, Isabele Santos Garcia, Alini Soriano Pereira, Rosemeire de Souza Santos, Louise Bach Kmetiuk, Andrea Pires dos Santos, Alexander Welker Biondo, Rogerio Giuffrida, Vamilton Alvares Santarem
Summary: The study experimentally assessed Nile tilapia as a potential paratenic host for Toxocara spp. It was found that despite shedding viable eggs through the gastrointestinal tract, tilapias may not play a role as a suitable paratenic host. Therefore, the risk of zoonotic transmission through fish meat consumption is low.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Article
Food Science & Technology
Brianna C. Britton, Ibrahima Sarr, Haley F. Oliver
Summary: This study in the Senegalese peanut basin revealed that over 20% of samples had microbial contamination and producers had low awareness of pathogens and aflatoxins. The type of storage container and method of peanut storage significantly influenced contamination levels.
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY
(2021)
Article
Environmental Sciences
Matthew Ming-Lok Leung, Yuen-Wa Ho, Cheng-Hao Lee, Youji Wang, Menghong Hu, Kevin Wing Hin Kwok, Song-Lin Chua, James Kar-Hei Fang
Summary: This study addressed the common technical challenges in assessing microplastics in seafood by developing an improved protocol based on Raman spectroscopy and chemical treatment. The findings confirmed the presence of microplastics in shellfish and fish collected from Hong Kong waters, mainly consisting of polypropylene, polyethylene, polystyrene, and poly(ethylene terephthalate). The developed method provides an improved alternative for routine monitoring of microplastics.
ENVIRONMENTAL POLLUTION
(2021)
Review
Food Science & Technology
Gabriela Maia Danielski, Alberto Goncalves Evangelista, Fernando Bittencourt Luciano, Renata Ernlund Freitas de Macedo
Summary: Meat and meat products are susceptible to pathogenic or spoilage bacteria, causing economic losses and public health threats. Non-conventional microorganisms and biometabolites have potential for bio protection, improving the quality and safety of meat products.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Review
Food Science & Technology
Alberto Goncalves Evangelista, Jessica Audrey Feijo Correa, Anne Caroline Schoch Marques Pinto, Fernando Bittencourt Luciano
Summary: Population growth affects global food supply by demanding higher production efficiency without expanding farmland due to limited land resources and biodiversity loss. The intense use of antibiotic growth promoters in animal production has been linked to antimicrobial resistance rise, leading to the emergence of multidrug-resistant pathogens and limiting treatment options. Essential oils and essential oil components have been studied as potential alternatives to antibiotics in animal production, showing antimicrobial effectiveness and potential for improving zootechnical indexes and modulating genes involved in resistance mechanisms.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Agriculture, Multidisciplinary
Victor Dopazo, Carlos Luz, Juan M. Quiles, Jorge Calpe, Raffaele Romano, Jordi Manes, Giuseppe Meca
Summary: The study revealed that four lactic acid bacteria strains have antifungal activity against grape contaminant fungi, with L. plantarum E3 fermented CFS showing the best reduction in growth of Botrytis cinerea and Aspergillus ochraceus in grapes.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2022)
Review
Food Science & Technology
Massimo Frangiamone, Alessandra Cimbalo, Manuel Alonso-Garrido, Pilar Vila-Donat, Lara Manyes
Summary: Due to globalization, mycotoxins have become a major food contaminant with significant risks to human health. This review focuses on the toxic effects of AFB1 and OTA, two of the most toxic and studied mycotoxins, on human health using flow cytometry and immunofluorescence techniques in vitro and in vivo. The majority of the selected reports examine immunotoxicity, while others explore nephrotoxicity, hepatotoxicity, gastrointestinal toxicity, neurotoxicity, embryotoxicity, reproductive system, breast, esophageal and lung toxicity. Immunofluorescence analysis reveals processes related to inflammation, neuronal differentiation, DNA damage, oxidative stress, and cell death caused by AFB1 and OTA toxicity. Flow cytometry analysis includes apoptosis assay, cell cycle analysis, and intracellular ROS measurement. Further research is needed to elucidate the mechanisms of action of AFB1 and OTA on human health.
FOOD AND CHEMICAL TOXICOLOGY
(2022)
Article
Food Science & Technology
Raquel Torrijos, Tiago Melo Nazareth, Jorge Calpe, Juan Manuel Quiles, Jordi Manes, Giuseppe Meca
Summary: This study found that natamycin has antifungal effects against Penicillium strains and the two applications on Mozzarella cheese slices significantly decreased the population of P. commune while extending the shelf life of the cheese. The use of natamycin-containing hydroxyethylcellulose films may be a viable alternative to direct applications on cheese, offering a biodegradable antifungal system without compromising food safety.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Food Science & Technology
Jessica Audrey Feijo Correa, Tiago de Melo Nazareth, Giuseppe Meca, Fernando Bittencourt Luciano
Summary: This study developed a rapid and affordable bacterial screening assay for detecting ochratoxin A (OTA) degradation capability, saving costs.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Food Science & Technology
Raquel Torrijos, Tiago de Melo Nazareth, Pilar Vila-Donat, Jordi Manes, Giuseppe Meca
Summary: This study investigated the antifungal properties of fermented mustard extracts against Fusarium fungus. The fermented yellow mustard, fermented by L. plantarum strains, showed significant inhibition of Fusarium species growth in vitro. Additionally, the fermented mustard extract demonstrated strong antimycotoxigenic activity, significantly reducing the content of FB1 and completely eliminating FB2 in contaminated corn ears.
Article
Food Science & Technology
Tiago Melo Nazareth, Raquel Torrijos, Karla Paiva Bocate, Jordi Manes, Fernando Bittencourt Luciano, Giuseppe Meca, Pilar Vila-Donat
Summary: The present study describes the manufacture of an antifungal device composed of oriental mustard flour and hydroxyethyl-cellulose (H-OMF) and evaluates its efficacy in inhibiting Aspergillus flavus growth and aflatoxin B1 (AFB(1)) production in almonds. The device showed significant antifungal activity and could effectively reduce the population of A. flavus and the production of AFB(1) in almonds.
Article
Food Science & Technology
Laura Escriva, Fojan Agahi, Pilar Vila-Donat, Jordi Manes, Giuseppe Meca, Lara Manyes
Summary: The presence of mycotoxins in cereals and cereal products is a significant issue. This study evaluated the bioaccessibility of aflatoxin B-1 (AFB1) and ochratoxin (OTA) in bread and investigated the effects of milk whey and pumpkin in reducing mycotoxins bioaccessibility. The results showed that pumpkin powder was the most effective in reducing AFB1 and OTA bioaccessibility, followed by whey, fermented whey, and the combination of pumpkin-fermented whey. These findings suggest that pumpkin and milk whey could be potential bioactive ingredients for the bakery industry.
Article
Food Science & Technology
Massimo Frangiamone, Manuel Lozano, Alessandra Cimbalo, Guillermina Font, Lara Manyes
Summary: Aflatoxin B1 (AFB1) and ochratoxin A (OTA) are common contaminants in food and feed, with detrimental effects on human and animal health even in low concentrations. A transcriptomic study on human lymphoblastic T cells revealed altered gene expressions caused by low doses of AFB1, OTA, and their combination. Significant differential gene expressions were observed in all conditions, with immune system-related processes and functions affected. Pathway analysis indicated potential DNA damage, metabolic reprogramming, and cell death with oxidative stress as mechanisms of immune toxicity.
Article
Toxicology
Massimo Frangiamone, Alexander Yemelin, Alessandra Cimbalo, Guillermina Font, Eckhard Thines, Lara Manyes
Summary: The study found that chronic exposure to hepatotoxic Aflatoxin B1 (AFB1) and nephrotoxic ochratoxin A (OTA) can cause liver and kidney damage, which can be counteracted by natural compounds like fermented whey (FW). By analyzing the altered gene expression of hepatic carbamoyl phosphate synthetase 1 (CPS1) and renal kidney injury molecule 1 (KIM-1) in male and female rats after 28 days of oral exposure, it was found that FW supplementation can attenuate the hepatotoxicity and nephrotoxicity induced by AFB1 and OTA.
TOXICOLOGY MECHANISMS AND METHODS
(2023)
Review
Food Science & Technology
Maria Vanessa Vila-Lopez, Noelia Pallares, Emilia Ferrer, Josefa Tolosa
Summary: Pseudo-cereals are becoming popular due to their health benefits, but studies on the presence of mycotoxins in these grains are limited. Similar to cereals, pseudo-cereals can be contaminated with mycotoxins, although levels are often lower. More research is needed to establish safe levels and ensure human and animal health.
Article
Food Science & Technology
Albert Sebastia, Mara Calleja-Gomez, Noelia Pallares, Francisco J. Barba, Houda Berrada, Emilia Ferrer
Summary: In recent years, innovative food processing technologies such as ultrasound (USN) and pulsed electric fields (PEF) have emerged in the market and have shown great potential for the preservation of food products. This study investigated the effectiveness of combined treatments using USN + PEF and PEF + USN on reducing mycotoxin levels in orange juice mixed with milk. The results showed promising applications for reducing mycotoxins, with the PEF + USN treatment combination achieving up to 50% reduction in OTA and up to 47% reduction in ENNB.
Article
Food Science & Technology
Massimo Frangiamone, Manuel Lozano, Alessandra Cimbalo, Alvaro Lazaro, Guillermina Font, Lara Manyes
Summary: The aim of this study was to investigate the potential beneficial effects of a pumpkin and fermented milk whey (FW) mixture on the gene expression profile in Jurkat cells exposed to aflatoxin B1 (AFB1) and ochratoxin A (OTA). The results showed that the exposure to AFB1-P-FW resulted in 34 differentially expressed genes (DEGs), while OTA-P-FW exposure led to 3450 DEGs and AFB1-OTA-P-FW treatment resulted in 3264 DEGs. Pathway analysis revealed that eicosanoid signaling via lipoxygenase was affected by AFB1-P-FW exposure, while interferon signaling was the most affected pathway after OTA-P-FW and AFB1-OTA-P-FW treatments. Overall, these findings suggest that the P-FW mixture may have anti-inflammatory and protective effects against AFB1 and OTA-induced gene alterations.
MOLECULAR NUTRITION & FOOD RESEARCH
(2023)
Article
Food Science & Technology
Giacomo Di Matteo, Alessandra Cimbalo, Lara Manyes, Luisa Mannina
Summary: G. lutea flower attenuates BEA cytotoxicity and reduces the presence of major oncoproteins through modulation of protein expression.
Article
Fisheries
Hunter S. Bailey, Ashley N. Fincannon, Lee A. Fuiman
Summary: This study investigated the transfer of fatty acids from broodstock diets to eggs and the time needed for the eggs to equilibrate to the diet in Southern flounder. The findings indicate that different diet treatments significantly affect the fatty acid composition of eggs, and it takes 8-16 weeks for the eggs to adapt to changes in the adult diet. These results are important for improving broodstock diets and feeding protocols in stock-enhancement programs.
Article
Fisheries
Yu Liu, Mingtao Lei, Hector Victor, Yan Wang
Summary: This study confirms the feasibility of replacing raw fish diet with a formulated diet in commercial farming of large yellow croaker, which can increase fish survival and yield, and reduce feed cost and body lipid deposition.
Article
Fisheries
Xiaoyan Zhang, Lize San, Yucong Yang, Yuehong Tao, Jiangong Ren, Yufeng Liu, Zhongwei He, Jiashuo Di, Ziteng Pei, Guixing Wang, Jilun Hou
Summary: Gynogenesis is an effective technique for establishing homogeneous lines and confirming potential chromosomal mechanisms of sex determination in fish. This study successfully induced gynogenetic families in Thamnaconus modestus and established a complete method for gynogenesis induction.
Article
Fisheries
Julieta C. Martinelli, Megan Considine, Helen R. Casendino, Carolyn M. Tarpey, Isadora Jimenez-Hidalgo, Jacqueline L. Padilla-Gamino, Teri L. King, Lorenz Hauser, Steven Rumrill, Chelsea L. Wood
Summary: Shell-boring polychaetes have caused significant damage to mariculture operations worldwide, particularly in the US Pacific region. This study provides a comprehensive dataset on the prevalence, species distribution, and environmental associations of these parasites, highlighting the impact of season, culturing methods, and environmental factors on infestation.
Article
Fisheries
Juan Gao, Xueshan Li, Kangle Lu, Kai Song, Jian Zhang, Ling Wang, Chunxiao Zhang
Summary: This study investigated the effects of dietary protein levels on growth performance, antioxidant capacity, digestive enzyme activity, and metamorphosis rate of bullfrog tadpoles. The optimal dietary protein level for bullfrog tadpoles was estimated to be 42.49%-46.50% of the diet.
Article
Fisheries
Qiang Li, Lijun Duan, Dongsheng Jin, Yuxin Chen, Yirong Lou, Qianjin Zhou, Zhongjie Xu, Fangjie Chen, Hongxian Chen, Guizong Xu, Maocang Yan, Guanjun Yang, Jianfei Lu, Yanjun Zhang, Jiong Chen
Summary: This study developed a centrifugal microfluidic chip with on-chip RPA to detect five pathogenic microorganisms. The chip enabled the parallel analysis of six genetic markers from a single sample and allowed for the highly automated detection of multiple samples. Compared with PCR and DNA sequencing, the on-chip RPA assay showed high sensitivity and specificity for detecting multiple pathogens in shrimp aquaculture.
Article
Fisheries
Xingchen Huo, Pengxu Wang, Fengxia Zhao, Qian Liu, Qingqing Tian, Lingjie Tang, Maolin Lv, Zhaohui Wei, Chunrong Yang, Jianguo Su
Summary: Bacterial diseases in aquaculture ponds have negative effects on sustainable development. The use of composite I20 biotherapy has been shown to effectively treat bacterial diseases in bullfrog ponds, providing a new strategy for controlling bacterial diseases in aquaculture.
Article
Fisheries
Peng Yin, Takaya Saito, Per Gunnar Fjelldal, Bjorn Tharandur Bjornsson, Sofie Charlotte Remo, Sandeep Sharma, Rolf Erik Olsen, Kristin Hamre
Summary: This study aims to investigate the effect of seasonal changes in temperature and photoperiod on the redox metabolism of Atlantic salmon at the molecular level. The research findings suggest that the changing photoperiod and temperature influenced the redox metabolism of Atlantic salmon, highlighting the importance of oxidative status in the ecological implications.
Article
Fisheries
Nicholas Oppong Mensah, Jeffery Kofi Asare, Emmanuel Tetteh-Doku Mensah, Ernest Christlieb Amrago, Frank Osei Tutu, Anthony Donkor
Summary: This study investigates aquaculture farmers' preference for climate-smart aquaculture insurance products, the challenges they face, and their preferred insurance coverage. The results show that farmers prefer Climate-Induced Aquaculture Stock Mortality Insurance and the most significant constraint is the delay in claim settlement.
Article
Fisheries
Qiu-Ping Chai, Pei Wu, Wei-Dan Jiang, Yang Liu, Hong-Mei Ren, Xiao-Wan Jin, Lin Feng, Xiao-Qiu Zhou
Summary: The study found that appropriate levels of potassium diformate (KDF) can enhance the immune defense and mediate the inflammatory process in fish, possibly through the regulation of T cell differentiation via JAK-STAT and NF-kappa B signaling pathways.
Article
Fisheries
Tian Zhu, Haomin Jia, Haopeng Zhang, Yujing Xiao, Cui Han, Jiaxin Yang
Summary: Chicken manure has significant effects on the cultivation of Chlorella and rotifers. The optimal amount of chicken manure extract for continuous cultivation is 10 mLL-1. Chicken manure can promote the growth of Chlorella and improve the fatty acid composition, indirectly enhancing the growth condition and fatty acid content of rotifers.
Article
Fisheries
Zheng Luo, Yang Yu, Zhenning Bao, Fuhua Li
Summary: This study analyzed the heritability and genetic correlation of two growth traits in Pacific white shrimp and evaluated the genomic prediction using different genomic selection models. The results showed that the NeuralNet model had the highest prediction accuracy and better prospects for predicting shrimp growth traits.
Article
Fisheries
Alberto Ruiz, Ignasi Sanahuja, Karl B. Andree, Dolors Furones, Paul G. Holhorea, Josep A. Calduch-Giner, Jose J. Pastor, Marc Vinas, Jaume Perez-Sanchez, Sofia Morais, Enric Gisbert
Summary: Supplementing diets with a combination of spice oleoresins can reduce lipid accumulation and inflammation in farmed fish. The combination of spice oleoresins also has an immunomodulatory effect on the fish's intestinal immune system, potentially offering anti-inflammatory benefits.
Article
Fisheries
Beibei Zhao, Renhui Mei, Le Li, Di Hu, Lei Li
Summary: This study reveals that JfCXCL8_L1a and JfCXCL8_L1b have different immune pathways, and JfCXCL8_L1b plays a significant role in enhancing the adaptive immunity of T cell-dependent antigen.
Article
Fisheries
Yuhang Liu, Danying Cao, Nan Wu, Xuyang Zhao, Qingsong Zhu, Lian Su, Fatima Altaf, Qianqian Zhang, Haokun Liu, Yongming Li, Bruno Hamish Unger, Yingyin Cheng, Wanting Zhang, Aihua Li, Yaping Wang, Xiao-Qin Xia
Summary: Based on previous research, sinomenine has been found to protect mucosal immunity in farmed fish species by preventing intestinal pathological changes and regulating gene expression related to inflammation. It also enhances immune homeostasis and controls the growth of pathogenic bacteria.