Nucleoside dimers analogues with a 1,2,3-triazole linkage: conjugation of floxuridine and thymidine provides novel tools for cancer treatment. Part II

Synthesis and biological assay of new 2’-deoxyuridine dimers containing a 1,2,3-triazole linker. Part I

(2018) Lucyna Michalska et al.   NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS

3′-O- and 5′-O-Propargyl Derivatives of 5-Fluoro-2′-Deoxyuridine: Synthesis, Cytotoxic Evaluation and Conformational Analysis

(2016) Dagmara Baraniak et al.   NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS

Bioactive nucleoside analogues possessing selected five-membered azaheterocyclic bases

(2015) Joanna Zeidler et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Are 1,4- and 1,5-Disubstituted 1,2,3-Triazoles Good Pharmacophoric Groups?

(2014) Alberto Massarotti et al.   ChemMedChem

Synthesis of 3′-azido-2′,3′-dideoxy-5-fluorouridine phosphoramidates and evaluation of their anticancer activity

(2013) Marta Lewandowska et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

15N NMR spectroscopic and theoretical GIAO-DFT studies for the unambiguous characterization of disubstituted 1,2,3-triazoles

(2013) Miriam Corredor et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Cytotoxicity of new duplex drugs linking 3′-C-ethynylcytidine and 5-fluor-2′-deoxyuridine against human melanoma cells

(2012) Sarah Schott et al.   INTERNATIONAL JOURNAL OF CANCER

Method for Assigning Structure of 1,2,3-Triazoles

(2012) Xavier Creary et al.   JOURNAL OF ORGANIC CHEMISTRY

The cytostatic activity of NUC-3073, a phosphoramidate prodrug of 5-fluoro-2′-deoxyuridine, is independent of activation by thymidine kinase and insensitive to degradation by phosphorolytic enzymes

(2011) Johan Vande Voorde et al.   BIOCHEMICAL PHARMACOLOGY

Novel Anticancer Polymeric Conjugates of Activated Nucleoside Analogues

(2011) Thulani H. Senanayake et al.   BIOCONJUGATE CHEMISTRY

Click Chemistry: 1,2,3-Triazoles as Pharmacophores

(2011) Sandip G. Agalave et al.   Chemistry-An Asian Journal

Phosphoramidate ProTides of the Anticancer Agent FUDR Successfully Deliver the Preformed Bioactive Monophosphate in Cells and Confer Advantage over the Parent Nucleoside

(2011) Christopher McGuigan et al.   JOURNAL OF MEDICINAL CHEMISTRY

Novel effects of glycyrrhetinic acid on the central nervous system tumorigenic progenitor cells: Induction of actin disruption and tumor cell-selective toxicity

(2010) Hideaki Yamaguchi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and in vitro activities of new anticancer duplex drugs linking 2′-deoxy-5-fluorouridine (5-FdU) with 3′-C-ethynylcytidine (ECyd) via a phosphodiester bonding

(2009) Herbert Schott et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Efficient construction of therapeutics, bioconjugates, biomaterials and bioactive surfaces using azide–alkyne “click” chemistry☆

(2008) J LUTZ et al.   ADVANCED DRUG DELIVERY REVIEWS

Cu-Catalyzed Azide−Alkyne Cycloaddition

(2008) Morten Meldal et al.   CHEMICAL REVIEWS