The cytostatic activity of NUC-3073, a phosphoramidate prodrug of 5-fluoro-2′-deoxyuridine, is independent of activation by thymidine kinase and insensitive to degradation by phosphorolytic enzymes

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Title
The cytostatic activity of NUC-3073, a phosphoramidate prodrug of 5-fluoro-2′-deoxyuridine, is independent of activation by thymidine kinase and insensitive to degradation by phosphorolytic enzymes
Authors
Keywords
-
Journal
BIOCHEMICAL PHARMACOLOGY
Volume 82, Issue 5, Pages 441-452
Publisher
Elsevier BV
Online
2011-06-06
DOI
10.1016/j.bcp.2011.05.024

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