XAB2 depletion induces intron retention in POLR2A to impair global transcription and promote cellular senescence

Structure and Conformational Dynamics of the Human Spliceosomal B act Complex

(2018) David Haselbach et al.   CELL

Structure of the human activated spliceosome in three conformational states

(2018) Xiaofeng Zhang et al.   CELL RESEARCH

OUP accepted manuscript

(2018)   NUCLEIC ACIDS RESEARCH

Structure of a human catalytic step I spliceosome

(2018) Xiechao Zhan et al.   SCIENCE

Hallmarks of Cellular Senescence

(2018) Alejandra Hernandez-Segura et al.   TRENDS IN CELL BIOLOGY

The PRIDE database and related tools and resources in 2019: improving support for quantification data

(2018) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

The Spliceosome: A Protein-Directed Metalloribozyme

(2017) Yigong Shi   JOURNAL OF MOLECULAR BIOLOGY

Cryo-EM structure of a human spliceosome activated for step 2 of splicing

(2017) Karl Bertram et al.   NATURE

Senescent cells: an emerging target for diseases of ageing

(2017) Bennett G. Childs et al.   NATURE REVIEWS DRUG DISCOVERY

Mechanistic insights into precursor messenger RNA splicing by the spliceosome

(2017) Yigong Shi   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The RNA Polymerase II CTD: The Increasing Complexity of a Low-Complexity Protein Domain

(2016) Célia Jeronimo et al.   JOURNAL OF MOLECULAR BIOLOGY

Coupling of RNA Polymerase II Transcription Elongation with Pre-mRNA Splicing

(2016) Tassa Saldi et al.   JOURNAL OF MOLECULAR BIOLOGY

Recurrent somatic mutations in POLR2A define a distinct subset of meningiomas

(2016) Victoria E Clark et al.   NATURE GENETICS

Molecular features of cellular reprogramming and development

(2016) Zachary D. Smith et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Tetratricopeptide repeat factor XAB2 mediates the end resection step of homologous recombination

(2016) David O. Onyango et al.   NUCLEIC ACIDS RESEARCH

Enrichr: a comprehensive gene set enrichment analysis web server 2016 update

(2016) Maxim V. Kuleshov et al.   NUCLEIC ACIDS RESEARCH

XAB2 functions in mitotic cell cycle progression via transcriptional regulation of CENPE

(2016) Shuai Hou et al.   Cell Death & Disease

Cell dynamics and gene expression control in tissue homeostasis and development

(2015) P. Rue et al.   Molecular Systems Biology

The RNA helicase Aquarius exhibits structural adaptations mediating its recruitment to spliceosomes

(2015) Inessa De et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Splicing inhibition decreases phosphorylation level of Ser2 in Pol II CTD

(2015) Mitsunori Koga et al.   NUCLEIC ACIDS RESEARCH

CWC22-dependent pre-mRNA splicing and eIF4A3 binding enables global deposition of exon junction complexes

(2015) Anna-Lena Steckelberg et al.   NUCLEIC ACIDS RESEARCH

The RNA helicase Aquarius exhibits structural adaptations mediating its recruitment to spliceosomes

(2015) Inessa De et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cellular senescence: from physiology to pathology

(2014) Daniel Muñoz-Espín et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Degradation of DNA damage-independently stalled RNA polymerase II is independent of the E3 ligase Elc1

(2014) Eleni Karakasili et al.   NUCLEIC ACIDS RESEARCH

Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool

(2013) Edward Y Chen et al.   BMC BIOINFORMATICS

SR Proteins Collaborate with 7SK and Promoter-Associated Nascent RNA to Release Paused Polymerase

(2013) Xiong Ji et al.   CELL

The Writers, Readers, and Functions of the RNA Polymerase II C-Terminal Domain Code

(2013) Célia Jeronimo et al.   CHEMICAL REVIEWS

The RNA Polymerase II Carboxy-Terminal Domain (CTD) Code

(2013) Dirk Eick et al.   CHEMICAL REVIEWS

Coherence between Cellular Responses andin VitroSplicing Inhibition for the Anti-tumor Drug Pladienolide B and Its Analogs

(2013) Kerstin A. Effenberger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Hbs1-Dom34 Protein Complex Functions in Non-stop mRNA Decay in Mammalian Cells

(2013) Syuhei Saito et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evidence that a consensus element found in naturally intronless mRNAs promotes mRNA export

(2012) Haixin Lei et al.   NUCLEIC ACIDS RESEARCH

Pre-mRNA splicing in disease and therapeutics

(2012) Ravi K. Singh et al.   TRENDS IN MOLECULAR MEDICINE

The Prp19 complex is a novel transcription elongation factor required for TREX occupancy at transcribed genes

(2011) S. Chanarat et al.   GENES & DEVELOPMENT

Integrative genomics viewer

(2011) James T Robinson et al.   NATURE BIOTECHNOLOGY

Controlling gene expression in response to stress

(2011) Eulàlia de Nadal et al.   NATURE REVIEWS GENETICS

Characterization of purified human Bact spliceosomal complexes reveals compositional and morphological changes during spliceosome activation and first step catalysis

(2010) S. Bessonov et al.   RNA

Dom34:Hbs1 Promotes Subunit Dissociation and Peptidyl-tRNA Drop-Off to Initiate No-Go Decay

(2010) C. J. Shoemaker et al.   SCIENCE

The Spliceosome: Design Principles of a Dynamic RNP Machine

(2009) Markus C. Wahl et al.   CELL

Mammalian Elongin A complex mediates DNA-damage-induced ubiquitylation and degradation of Rpb1

(2008) Takashi Yasukawa et al.   EMBO JOURNAL

Coupling and coordination in gene expression processes: a systems biology view

(2007) Suzanne Komili et al.   NATURE REVIEWS GENETICS