Splicing inhibition decreases phosphorylation level of Ser2 in Pol II CTD

3' end formation of pre-mRNA and phosphorylation of Ser2 on the RNA polymerase II CTD are reciprocally coupled in human cells

(2014) L. Davidson et al.   GENES & DEVELOPMENT

A Splicing-Dependent Transcriptional Checkpoint Associated with Prespliceosome Formation

(2014) Keerthi T. Chathoth et al.   MOLECULAR CELL

U2 snRNP Is Required for Expression of the 3′ End of Genes

(2014) Mitsunori Koga et al.   PLoS One

SR Proteins Collaborate with 7SK and Promoter-Associated Nascent RNA to Release Paused Polymerase

(2013) Xiong Ji et al.   CELL

Splicing-coupled 3′ end formation requires a terminal splice acceptor site, but not intron excision

(2013) Lee Davidson et al.   NUCLEIC ACIDS RESEARCH

Minor introns are embedded molecular switches regulated by highly unstable U6atac snRNA

(2013) Ihab Younis et al.   eLife

RNA Polymerase II Elongation Control

(2012) Qiang Zhou et al.   Annual Review of Biochemistry

Dynamic phosphorylation patterns of RNA polymerase II CTD during transcription

(2012) Martin Heidemann et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Transcription elongation factors DSIF and NELF: Promoter-proximal pausing and beyond

(2012) Yuki Yamaguchi et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Splicing in oncogenesis and tumor suppression

(2012) Daisuke Kaida et al.   CANCER SCIENCE

The RNA polymerase II CTD coordinates transcription and RNA processing

(2012) J.-P. Hsin et al.   GENES & DEVELOPMENT

Conservation between the RNA Polymerase I, II, and III Transcription Initiation Machineries

(2012) Alessandro Vannini et al.   MOLECULAR CELL

Gene-specific requirement of RNA polymerase II CTD phosphorylation

(2012) Julie Drogat et al.   MOLECULAR MICROBIOLOGY

CTD serine-2 plays a critical role in splicing and termination factor recruitment to RNA polymerase II in vivo

(2012) Bo Gu et al.   NUCLEIC ACIDS RESEARCH

Vezf1 protein binding sites genome-wide are associated with pausing of elongating RNA polymerase II

(2012) H. Gowher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Updating the RNA polymerase CTD code: adding gene-specific layers

(2012) Sylvain Egloff et al.   TRENDS IN GENETICS

Biological validation that SF3b is a target of the antitumor macrolide pladienolide

(2011) Akira Yokoi et al.   FEBS Journal

The Cyclin K/Cdk12 complex maintains genomic stability via regulation of expression of DNA damage response genes

(2011) D. Blazek et al.   GENES & DEVELOPMENT

Spliceosome assembly is coupled to RNA polymerase II dynamics at the 3′ end of human genes

(2011) Sandra Bento Martins et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Spliceostatin A blocks angiogenesis by inhibiting global gene expression including VEGF

(2010) Ryohei Furumai et al.   CANCER SCIENCE

CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1

(2010) B. Bartkowiak et al.   GENES & DEVELOPMENT

CDKN1C Negatively Regulates RNA Polymerase II C-terminal Domain Phosphorylation in an E2F1-dependent Manner

(2010) Yihong Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

U1 snRNP protects pre-mRNAs from premature cleavage and polyadenylation

(2010) Daisuke Kaida et al.   NATURE

Garbled messages and corrupted translations

(2010) Tilman Schneider-Poetsch et al.   Nature Chemical Biology

Spliceosome Structure and Function

(2010) C. L. Will et al.   Cold Spring Harbor Perspectives in Biology

The Spliceosome: Design Principles of a Dynamic RNP Machine

(2009) Markus C. Wahl et al.   CELL

Progression through the RNA Polymerase II CTD Cycle

(2009) Stephen Buratowski   MOLECULAR CELL

The multi-tasking P-TEFb complex

(2008) Vanessa Brès et al.   CURRENT OPINION IN CELL BIOLOGY

The splicing factor SC35 has an active role in transcriptional elongation

(2008) Shengrong Lin et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY