WITER: a powerful method for estimation of cancer-driver genes using a weighted iterative regression modelling background mutation counts

RIT1 oncoproteins escape LZTR1-mediated proteolysis

(2019) Pau Castel et al.   SCIENCE

Elevated SLC6A6 expression drives tumorigenesis and affects clinical outcomes in gastric cancer

(2019) Wang Dazhi et al.   Biomarkers in Medicine

Comprehensive Characterization of Cancer Driver Genes and Mutations

(2018) Matthew H. Bailey et al.   CELL

Transcriptomic analysis of CIC and ATXN1L reveal a functional relationship exploited by cancer

(2018) Derek Wong et al.   ONCOGENE

ZC3H13 suppresses colorectal cancer proliferation and invasion via inactivating Ras-ERK signaling

(2018) Dehua Zhu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Mutations in LZTR1 drive human disease by dysregulating RAS ubiquitination

(2018) M. Steklov et al.   SCIENCE

LZTR1 is a regulator of RAS ubiquitination and signaling

(2018) Johannes W. Bigenzahn et al.   SCIENCE

WT1 loss attenuates the TP53-induced DNA damage response in T-cell acute lymphoblastic leukemia

(2017) Fulvio Bordin et al.   HAEMATOLOGICA

Identification of a novel PML-RARG fusion in acute promyelocytic leukemia

(2017) J-S Ha et al.   LEUKEMIA

The evolving genomic landscape of urothelial carcinoma

(2017) Alexander P. Glaser et al.   Nature Reviews Urology

Impact of mutations in Toll-like receptor pathway genes on esophageal carcinogenesis

(2017) Daffolyn Rachael Fels Elliott et al.   PLoS Genetics

WT1 loss attenuates the TP53-induced DNA damage response in T-cell acute lymphoblastic leukemia

(2017) Fulvio Bordin et al.   HAEMATOLOGICA

Characterization of functionally active gene fusions in human papillomavirus related oropharyngeal squamous cell carcinoma

(2016) Theresa Guo et al.   INTERNATIONAL JOURNAL OF CANCER

Landscape of somatic mutations in 560 breast cancer whole-genome sequences

(2016) Serena Nik-Zainal et al.   NATURE

Data-driven hypothesis weighting increases detection power in genome-scale multiple testing

(2016) Nikolaos Ignatiadis et al.   NATURE METHODS

Role of non-coding sequence variants in cancer

(2016) Ekta Khurana et al.   NATURE REVIEWS GENETICS

Evaluating the evaluation of cancer driver genes

(2016) Collin J. Tokheim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enhancement of Proliferation and Invasion of Gastric Cancer Cell by KDM5C Via Decrease in p53 Expression

(2016) Liming Xu et al.   TECHNOLOGY IN CANCER RESEARCH & TREATMENT

Cell-of-origin chromatin organization shapes the mutational landscape of cancer

(2015) Paz Polak et al.   NATURE

New and emerging factors in tumorigenesis: an overview

(2015) Suwon Kim   Cancer Management and Research

Mutational Landscape of Aggressive Cutaneous Squamous Cell Carcinoma

(2014) C. R. Pickering et al.   CLINICAL CANCER RESEARCH

Critical role of retinoid/rexinoid signaling in mediating transformation and therapeutic response of NUP98-RARG leukemia

(2014) J J Qiu et al.   LEUKEMIA

A general framework for estimating the relative pathogenicity of human genetic variants

(2014) Martin Kircher et al.   NATURE GENETICS

A framework for the interpretation of de novo mutation in human disease

(2014) Kaitlin E Samocha et al.   NATURE GENETICS

Genomic and molecular characterization of esophageal squamous cell carcinoma

(2014) De-Chen Lin et al.   NATURE GENETICS

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

(2014) Anubha Mahajan et al.   NATURE GENETICS

OncodriveCLUST: exploiting the positional clustering of somatic mutations to identify cancer genes

(2013) David Tamborero et al.   BIOINFORMATICS

Mutational heterogeneity in cancer and the search for new cancer-associated genes

(2013) Michael S. Lawrence et al.   NATURE

Pan-cancer patterns of somatic copy number alteration

(2013) Travis I Zack et al.   NATURE GENETICS

Cancer Genome Landscapes

(2013) B. Vogelstein et al.   SCIENCE

MuSiC: Identifying mutational significance in cancer genomes

(2012) N. D. Dees et al.   GENOME RESEARCH

Chromatin organization is a major influence on regional mutation rates in human cancer cells

(2012) Benjamin Schuster-Böckler et al.   NATURE

Functional impact bias reveals cancer drivers

(2012) Abel Gonzalez-Perez et al.   NUCLEIC ACIDS RESEARCH

DNA replication timing and selection shape the landscape of nucleotide variation in cancer genomes

(2012) Yong H Woo et al.   Nature Communications