Closing the DNA replication cycle: from simple circular molecules to supercoiled and knotted DNA catenanes

The bacterial cell cycle, chromosome inheritance and cell growth

(2019) Rodrigo Reyes-Lamothe et al.   NATURE REVIEWS MICROBIOLOGY

Direct imaging of the circular chromosome in a live bacterium

(2019) Fabai Wu et al.   Nature Communications

DNA Supercoiling, Topoisomerases, and Cohesin: Partners in Regulating Chromatin Architecture?

(2018) Camilla Björkegren et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Why Two? On the Role of (A-)Symmetry in Negative Supercoiling of DNA by Gyrase

(2018) Dagmar Klostermeier   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Two convergent pathways of DNA knotting in replicating DNA molecules as revealed by θ-curve analysis

(2018) Danielle O’Donnol et al.   NUCLEIC ACIDS RESEARCH

Kinetic pathways of topology simplification by Type-II topoisomerases in knotted supercoiled DNA

(2018) Riccardo Ziraldo et al.   NUCLEIC ACIDS RESEARCH

Single-molecule imaging of DNA gyrase activity in living Escherichia coli

(2018) Mathew Stracy et al.   NUCLEIC ACIDS RESEARCH

Replication Fork Reversal: Players and Guardians

(2017) Annabel Quinet et al.   MOLECULAR CELL

Activities of gyrase and topoisomerase IV on positively supercoiled DNA

(2017) Rachel E. Ashley et al.   NUCLEIC ACIDS RESEARCH

DNA knots occur in intracellular chromatin

(2017) Antonio Valdés et al.   NUCLEIC ACIDS RESEARCH

Analysis of DNA topology of EBV minichromosomes in HEK 293 cells

(2017) Alicia Castán et al.   PLoS One

How topoisomerase IV can efficiently unknot and decatenate negatively supercoiled DNA molecules without causing their torsional relaxation

(2016) Eric J. Rawdon et al.   NUCLEIC ACIDS RESEARCH

MatP regulates the coordinated action of topoisomerase IV and MukBEF in chromosome segregation

(2016) Sophie Nolivos et al.   Nature Communications

The Causes and Consequences of Topological Stress during DNA Replication

(2016) Andrea Keszthelyi et al.   Genes

Regulation of DNA Replication Initiation by Chromosome Structure

(2015) David Magnan et al.   JOURNAL OF BACTERIOLOGY

Direct Evidence for the Formation of Precatenanes during DNA Replication

(2015) Jorge Cebrián et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fork rotation and DNA precatenation are restricted during DNA replication to prevent chromosomal instability

(2015) Stephanie A. Schalbetter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural diversity of supercoiled DNA

(2015) Rossitza N. Irobalieva et al.   Nature Communications

Mechanism of Transcriptional Bursting in Bacteria

(2014) Shasha Chong et al.   CELL

Electrophoretic mobility of supercoiled, catenated and knotted DNA molecules

(2014) Jorge Cebrián et al.   NUCLEIC ACIDS RESEARCH

Single-Molecule Reconstruction of Oligonucleotide Secondary Structure by Atomic Force Microscopy

(2014) Alice Pyne et al.   Small

DNA topology and transcription

(2014) Fedor Kouzine et al.   Nucleus

The benefit of DNA supercoiling during replication

(2013) Jorge B. Schvartzman et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Supercoiling in DNA and chromatin

(2013) Nick Gilbert et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Transcription-generated torsional stress destabilizes nucleosomes

(2013) Sheila S Teves et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

High-Resolution Mapping of the Spatial Organization of a Bacterial Chromosome

(2013) T. B. K. Le et al.   SCIENCE

2D gels and their third-dimension potential

(2012) Jorge B. Schvartzman et al.   METHODS

Unlinking of Supercoiled DNA Catenanes by Type IIA Topoisomerases

(2011) Alexander Vologodskii   BIOPHYSICAL JOURNAL

DNA knots and DNA supercoiling

(2011) Guillaume Witz et al.   CELL CYCLE

Topo IV is the topoisomerase that knots and unknots sister duplexes during DNA replication

(2011) Virginia López et al.   NUCLEIC ACIDS RESEARCH

Tightening of DNA knots by supercoiling facilitates their unknotting by type II DNA topoisomerases

(2011) Guillaume Witz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Positive Supercoiling of Mitotic DNA Drives Decatenation by Topoisomerase II in Eukaryotes

(2011) J. Baxter et al.   SCIENCE

Strong intranucleoid interactions organize the Escherichia coli chromosome into a nucleoid filament

(2010) P. A. Wiggins et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A human 5′-tyrosyl DNA phosphodiesterase that repairs topoisomerase-mediated DNA damage

(2009) Felipe Cortes Ledesma et al.   NATURE

Interplay of DNA supercoiling and catenation during the segregation of sister duplexes

(2009) M. L. Martinez-Robles et al.   NUCLEIC ACIDS RESEARCH

DNA supercoiling and its role in DNA decatenation and unknotting

(2009) Guillaume Witz et al.   NUCLEIC ACIDS RESEARCH

Simulation of DNA catenanes

(2009) Alexander Vologodskii et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Independent Positioning and Action of Escherichia coli Replisomes in Live Cells

(2008) Rodrigo Reyes-Lamothe et al.   CELL

DNA supercoiling inhibits DNA knotting

(2008) Y. Burnier et al.   NUCLEIC ACIDS RESEARCH

SV40 DNA replication: From the A gene to a nanomachine

(2008) Ellen Fanning et al.   VIROLOGY