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Title
Molecular Mechanisms and Therapeutics for SCA17
Authors
Keywords
Polyglutamine, SCA17, TBP, transcription, neurodegeneration, muscle atrophy
Journal
Neurotherapeutics
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-07-18
DOI
10.1007/s13311-019-00762-z
References
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Note: Only part of the references are listed.- The Expanding Clinical Universe of Polyglutamine Disease
- (2019) Shanshan Huang et al. NEUROSCIENTIST
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- (2019) Chiung-Mei Chen et al. Aging-US
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- (2018) Jifeng Guo et al. Molecular Neurodegeneration
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- (2018) Chiung-Mei Chen et al. NEUROTOXICOLOGY
- CRISPR/Cas9-mediated gene editing ameliorates neurotoxicity in mouse model of Huntington’s disease
- (2017) Su Yang et al. JOURNAL OF CLINICAL INVESTIGATION
- Synergistic Toxicity of Polyglutamine-Expanded TATA-Binding Protein in Glia and Neuronal Cells: Therapeutic Implications for Spinocerebellar Ataxia 17
- (2017) Yang Yang et al. JOURNAL OF NEUROSCIENCE
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- (2017) Karen L. Maxwell MOLECULAR CELL
- BIIB021, a synthetic Hsp90 inhibitor, induces mutant ataxin-1 degradation through the activation of heat shock factor 1
- (2016) Ying Ding et al. NEUROSCIENCE
- A patient with 41 CAG repeats in SCA17 presenting with parkinsonism and chorea
- (2016) Hyeyoung Park et al. PARKINSONISM & RELATED DISORDERS
- An miRNA-mediated therapy for SCA6 blocks IRES-driven translation of the CACNA1A second cistron
- (2016) Yu Miyazaki et al. Science Translational Medicine
- Gene suppression strategies for dominantly inherited neurodegenerative diseases: lessons from Huntington's disease and spinocerebellar ataxia
- (2015) Megan S. Keiser et al. HUMAN MOLECULAR GENETICS
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- (2015) Y. Dong et al. JOURNAL OF PERIODONTAL RESEARCH
- Trehalose Attenuates the Gait Ataxia and Gliosis of Spinocerebellar Ataxia Type 17 Mice
- (2015) Zhi-Zhong Chen et al. NEUROCHEMICAL RESEARCH
- Large Polyglutamine Repeats Cause Muscle Degeneration in SCA17 Mice
- (2015) Shanshan Huang et al. Cell Reports
- Nonallele Specific Silencing of Ataxin-7 Improves Disease Phenotypes in a Mouse Model of SCA7
- (2014) Pavitra S Ramachandran et al. MOLECULAR THERAPY
- Age-Dependent Decrease in Chaperone Activity Impairs MANF Expression, Leading to Purkinje Cell Degeneration in Inducible SCA17 Mice
- (2014) Su Yang et al. NEURON
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- (2014) Alessia Alibardi et al. PARKINSONISM & RELATED DISORDERS
- Peripheral Androgen Receptor Gene Suppression Rescues Disease in Mouse Models of Spinal and Bulbar Muscular Atrophy
- (2014) Andrew P. Lieberman et al. Cell Reports
- Automated home cage assessment shows behavioral changes in a transgenic mouse model of spinocerebellar ataxia type 17
- (2013) Esteban Portal et al. BEHAVIOURAL BRAIN RESEARCH
- A Novel Transgenic Rat Model for Spinocerebellar Ataxia Type 17 Recapitulates Neuropathological Changes and Supplies In Vivo Imaging Biomarkers
- (2013) A. Kelp et al. JOURNAL OF NEUROSCIENCE
- Silencing Mutant ATXN3 Expression Resolves Molecular Phenotypes in SCA3 Transgenic Mice
- (2013) Edgardo Rodríguez-Lebrón et al. MOLECULAR THERAPY
- Late onset ataxia: MSA-C or SCA 17? A gene penetrance dilemma
- (2013) Karen M. Doherty et al. MOVEMENT DISORDERS
- Hsp104 Suppresses Polyglutamine-Induced Degeneration Post Onset in a Drosophila MJD/SCA3 Model
- (2013) Mimi Cushman-Nick et al. PLoS Genetics
- The unfolded protein response: controlling cell fate decisions under ER stress and beyond
- (2012) Claudio Hetz NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Neuronal expression of TATA box-binding protein containing expanded polyglutamine in knock-in mice reduces chaperone protein response by impairing the function of nuclear factor-Y transcription factor
- (2011) Shanshan Huang et al. BRAIN
- A Drosophila model of the neurodegenerative disease SCA17 reveals a role of RBP-J/Su(H) in modulating the pathological outcome
- (2011) Jie Ren et al. HUMAN MOLECULAR GENETICS
- Neuroprotective effects of granulocyte-colony stimulating factor in a novel transgenic mouse model of SCA17
- (2011) Ya-Chin Chang et al. JOURNAL OF NEUROCHEMISTRY
- Pathology of CAG repeat diseases
- (2010) Mitsunori Yamada et al. NEUROPATHOLOGY
- Transcriptional dysregulation of TrkA associates with neurodegeneration in spinocerebellar ataxia type 17
- (2009) A. G. Shah et al. HUMAN MOLECULAR GENETICS
- Mesencephalic Astrocyte-Derived Neurotrophic Factor Is Neurorestorative in Rat Model of Parkinson's Disease
- (2009) M. H. Voutilainen et al. JOURNAL OF NEUROSCIENCE
- Huntington's disease-like and ataxia syndromes: Identification of a family with a de novo SCA17/TBP mutation
- (2009) Sara Bech et al. PARKINSONISM & RELATED DISORDERS
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- (2009) Jun Soo Bang et al. ARTHRITIS RESEARCH & THERAPY
- Polyglutamine Expansion Reduces the Association of TATA-binding Protein with DNA and Induces DNA Binding-independent Neurotoxicity
- (2008) Meyer J. Friedman et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- In vivo suppression of polyglutamine neurotoxicity by C-terminus of Hsp70-interacting protein (CHIP) supports an aggregation model of pathogenesis
- (2008) Aislinn J. Williams et al. NEUROBIOLOGY OF DISEASE
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