Increased matrix metalloproteinases expression in tuberous sclerosis complex: modulation by microRNA 146a and 147b in vitro

Inhibition of mTOR protects the blood-brain barrier in models of Alzheimer’s disease and vascular cognitive impairment

(2018) Candice E. Van Skike et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

mTOR dysregulation and tuberous sclerosis-related epilepsy

(2018) Paolo Curatolo et al.   Expert Review of Neurotherapeutics

miR147b: A novel key regulator of interleukin 1 beta-mediated inflammation in human astrocytes

(2018) Jackelien van Scheppingen et al.   GLIA

mTOR dysregulation and tuberous sclerosis-related epilepsy

(2018) Paolo Curatolo et al.   Expert Review of Neurotherapeutics

Increased expression of matrix metalloproteinase 3 can be attenuated by inhibition of microRNA-155 in cultured human astrocytes

(2018) Anatoly Korotkov et al.   Journal of Neuroinflammation

Increased expression of (immuno)proteasome subunits during epileptogenesis is attenuated by inhibition of the mammalian target of rapamycin pathway

(2017) Diede W. M. Broekaart et al.   EPILEPSIA

Blockade of the IL-1R1/TLR4 pathway mediates disease-modification therapeutic effects in a model of acquired epilepsy

(2017) Valentina Iori et al.   NEUROBIOLOGY OF DISEASE

Coding and small non-coding transcriptional landscape of tuberous sclerosis complex cortical tubers: implications for pathophysiology and treatment

(2017) James D. Mills et al.   Scientific Reports

Systematic review and meta-analysis of differentially expressed miRNAs in experimental and human temporal lobe epilepsy

(2017) A. Korotkov et al.   Scientific Reports

Centre of epileptogenic tubers generate and propagate seizures in tuberous sclerosis

(2016) Lakshminarayanan Kannan et al.   BRAIN

Early onset epileptic encephalopathy or genetically determined encephalopathy with early onset epilepsy? Lessons learned from TSC

(2016) Paolo Curatolo et al.   EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY

Matrix metalloproteinases in the brain and blood–brain barrier: Versatile breakers and makers

(2016) Ralf G Rempe et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Dysregulation of the (immuno)proteasome pathway in malformations of cortical development

(2016) J. van Scheppingen et al.   Journal of Neuroinflammation

Role of Matrix Metalloproteinases in Animal Models of Ischemic Stroke

(2015) Sebastien Lenglet et al.   Current Vascular Pharmacology

miR-146a targets Fos expression in human cardiac cells

(2015) Xavier Palomer et al.   Disease Models & Mechanisms

The role of TIMPs in regulation of extracellular matrix proteolysis

(2015) Valerie Arpino et al.   MATRIX BIOLOGY

Blood–brain barrier dysfunction, seizures and epilepsy

(2015) E.A. van Vliet et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Distributions of Irritative Zones Are Related to Individual Alterations of Resting-State Networks in Focal Epilepsy

(2015) Yinchen Song et al.   PLoS One

TIMP-2 Interaction with MT1-MMP Activates the AKT Pathway and Protects Tumor Cells from Apoptosis

(2015) Cristina Valacca et al.   PLoS One

Evolving neurobiology of tuberous sclerosis complex

(2013) Peter B. Crino   ACTA NEUROPATHOLOGICA

Increased metalloprotease activity in the epileptogenic lesion—Lobectomy reduces metalloprotease activity and urokinase-type uPAR circulating levels

(2013) Thereza Quirico-Santos et al.   BRAIN RESEARCH

Differential expression of major histocompatibility complex class I in developmental glioneuronal lesions

(2013) Avanita S Prabowo et al.   Journal of Neuroinflammation

MMP-9 Inhibition: a Therapeutic Strategy in Ischemic Stroke

(2013) Mayank Chaturvedi et al.   MOLECULAR NEUROBIOLOGY

Hippocampal subregion-specific microRNA expression during epileptogenesis in experimental temporal lobe epilepsy

(2013) Jan A. Gorter et al.   NEUROBIOLOGY OF DISEASE

Fetal Brain Lesions in Tuberous Sclerosis Complex: TORC1 Activation and Inflammation

(2012) Avanita S. Prabowo et al.   BRAIN PATHOLOGY

Increased expression of matrix metalloproteinase 9 in cortical lesions from patients with focal cortical dysplasia type IIb and tuberous sclerosis complex

(2012) Song Li et al.   BRAIN RESEARCH

Genome-wide microRNA profiling of human temporal lobe epilepsy identifies modulators of the immune response

(2012) Anne A. Kan et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Blood-brain barrier dysfunction and epilepsy: Pathophysiologic role and therapeutic approaches

(2012) Nicola Marchi et al.   EPILEPSIA

Matrix metalloproteinase-9 (MMP-9) in human intractable epilepsy caused by focal cortical dysplasia

(2012) Anna Konopka et al.   EPILEPSY RESEARCH

Matrix metalloproteinase-3 in the central nervous system: a look on the bright side

(2012) Inge Van Hove et al.   JOURNAL OF NEUROCHEMISTRY

MicroRNA-146a: A Key Regulator of Astrocyte-Mediated Inflammatory Response

(2012) Anand Iyer et al.   PLoS One

Blood-brain barrier dysfunction, status epilepticus, seizures, and epilepsy: A puzzle of a chicken and egg?

(2011) Alon Friedman   EPILEPSIA

Caveolin-1 regulates nitric oxide-mediated matrix metalloproteinases activity and blood-brain barrier permeability in focal cerebral ischemia and reperfusion injury

(2011) Yong Gu et al.   JOURNAL OF NEUROCHEMISTRY

Matrix Metalloproteinase-2 and -9 Secreted by Leukemic Cells Increase the Permeability of Blood-Brain Barrier by Disrupting Tight Junction Proteins

(2011) Saran Feng et al.   PLoS One

MiR-146a suppresses tumor growth and progression by targeting EGFR pathway and in a p-ERK-dependent manner in castration-resistant prostate cancer

(2011) Bin Xu et al.   PROSTATE

MicroRNAs in Human Diseases: From Cancer to Cardiovascular Disease

(2011) Tai-You Ha   Immune Network

The tissue inhibitors of metalloproteinases (TIMPs): An ancient family with structural and functional diversity

(2010) Keith Brew et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Intracellular substrate cleavage: a novel dimension in the biochemistry, biology and pathology of matrix metalloproteinases

(2010) Bénédicte Cauwe et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Expression pattern of miR-146a, an inflammation-associated microRNA, in experimental and human temporal lobe epilepsy

(2010) E. Aronica et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Metzincin Proteases and Their Inhibitors: Foes or Friends in Nervous System Physiology?

(2010) S. Rivera et al.   JOURNAL OF NEUROSCIENCE

The role of hypoxia-inducible factor-1α, aquaporin-4, and matrix metalloproteinase-9 in blood-brain barrier disruption and brain edema after traumatic brain injury

(2010) Tetsuhiro Higashida et al.   JOURNAL OF NEUROSURGERY

Matrix metalloproteinase-dependent shedding of intercellular adhesion molecule-5 occurs with long-term potentiation

(2010) K. Conant et al.   NEUROSCIENCE

Gene Expression Analysis of Tuberous Sclerosis Complex Cortical Tubers Reveals Increased Expression of Adhesion and Inflammatory Factors

(2009) Karin Boer et al.   BRAIN PATHOLOGY

Involvement of PI3K/PTEN/AKT/mTOR pathway in invasion and metastasis in hepatocellular carcinoma: Association with MMP-9

(2009) Jing-song Chen et al.   HEPATOLOGY RESEARCH

Doxycycline inhibits matrix metalloproteinase-9 and laminin degradation after transient global cerebral ischemia

(2009) Hyung Lee et al.   NEUROBIOLOGY OF DISEASE

Amplification efficiency: linking baseline and bias in the analysis of quantitative PCR data

(2009) J. M. Ruijter et al.   NUCLEIC ACIDS RESEARCH

Management of epilepsy in tuberous sclerosis complex

(2008) P Curatolo et al.   Expert Review of Neurotherapeutics

Tuberous sclerosis

(2008) Paolo Curatolo et al.   LANCET

Expression of microRNA-146 suppresses NF-κB activity with reduction of metastatic potential in breast cancer cells

(2008) D Bhaumik et al.   ONCOGENE

Activity-Dependent Shedding of the NMDA Receptor Glycine Binding Site by Matrix Metalloproteinase 3: A PUTATIVE Mechanism of Postsynaptic Plasticity

(2008) Thorsten Pauly et al.   PLoS One

Endogenous Matrix Metalloproteinase (MMP)-3 and MMP-9 Promote the Differentiation and Migration of Adult Neural Progenitor Cells in Response to Chemokines

(2008) Basam Z. Barkho et al.   STEM CELLS

Inflammatory processes in cortical tubers and subependymal giant cell tumors of tuberous sclerosis complex

(2007) K. Boer et al.   EPILEPSY RESEARCH