Triptolide Improves Cognitive Dysfunction in Rats with Vascular Dementia by Activating the SIRT1/PGC-1α Signaling Pathway

Nimodipine represses AMPK phosphorylation and excessive autophagy after chronic cerebral hypoperfusion in rats

(2018) Yan Chen et al.   BRAIN RESEARCH BULLETIN

Crocin attenuates acute hypobaric hypoxia-induced cognitive deficits of rats

(2018) Xiao-yan Zhang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

SIRT1/PGC-1α Signaling Promotes Mitochondrial Functional Recovery and Reduces Apoptosis after Intracerebral Hemorrhage in Rats

(2018) Yang Zhou et al.   Frontiers in Molecular Neuroscience

Galactosylated chitosan Triptolide nanoparticles for overcoming hepatocellular carcinoma: Enhanced therapeutic efficacy, low toxicity, and validated network regulatory mechanisms

(2018) Yan-Qiong Zhang et al.   Nanomedicine-Nanotechnology Biology and Medicine

Decline in Sirtuin-1 expression and activity plays a critical role in blood-brain barrier permeability in aging

(2018) Svetlana M. Stamatovic et al.   NEUROBIOLOGY OF DISEASE

Treadmill Exercise Attenuates α-Synuclein Levels by Promoting Mitochondrial Function and Autophagy Possibly via SIRT1 in the Chronic MPTP/P-Induced Mouse Model of Parkinson’s Disease

(2017) Jung-Hoon Koo et al.   NEUROTOXICITY RESEARCH

Oxidative Stress in Vascular Dementia and Alzheimer's Disease: A Common Pathology

(2017) Stuart Bennett et al.   JOURNAL OF ALZHEIMERS DISEASE

Stroke injury, cognitive impairment and vascular dementia

(2016) Raj N. Kalaria et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Triptolide Modulates TREM-1 Signal Pathway to Inhibit the Inflammatory Response in Rheumatoid Arthritis

(2016) Danping Fan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Update on Vascular Dementia

(2016) Ayesha Khan et al.   JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY

Molecular Mechanisms of Vascular Dementia: What Can Be Learned from Animal Models of Chronic Cerebral Hypoperfusion?

(2016) Si-Qi Du et al.   MOLECULAR NEUROBIOLOGY

Salvia miltiorrhiza extract protects white matter and the hippocampus from damage induced by chronic cerebral hypoperfusion in rats

(2015) Min-Soo Kim et al.   BMC Complementary and Alternative Medicine

Triptolide Protects Against Ischemic Stroke in Rats

(2015) Maolin Hao et al.   INFLAMMATION

Astrocytes Protect Neurons from Aβ1-42 Peptide-Induced Neurotoxicity Increasing TFAM and PGC-1 and Decreasing PPAR-γ and SIRT-1

(2015) Diana Aguirre-Rueda et al.   International Journal of Medical Sciences

Diabetes augments cognitive dysfunction in chronic cerebral hypoperfusion by increasing neuronal cell death: Implication of cilostazol for diabetes mellitus-induced dementia

(2015) Kyoung Ja Kwon et al.   NEUROBIOLOGY OF DISEASE

Biomarkers of Brain Damage: S100B and NSE Concentrations in Cerebrospinal Fluid—A Normative Study

(2015) Lenka Hajduková et al.   Biomed Research International

Hypercholesterolaemia-induced oxidative stress at the blood–brain barrier

(2014) Irundika H.K. Dias et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Triptolide: Progress on research in pharmacodynamics and toxicology

(2014) Xiao-Jiaoyang Li et al.   JOURNAL OF ETHNOPHARMACOLOGY

Alpha-lipoic acid upregulates SIRT1-dependent PGC-1α expression and protects mouse brain against focal ischemia

(2014) B. Fu et al.   NEUROSCIENCE

Triptolide Preserves Cognitive Function and Reduces Neuropathology in a Mouse Model of Alzheimer's Disease

(2014) Shaowu Cheng et al.   PLoS One

Vascular Aspects of Cognitive Impairment and Dementia

(2013) Maximilian Wiesmann et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Effects of acupuncture on declined cerebral blood flow, impaired mitochondrial respiratory function and oxidative stress in multi-infarct dementia rats

(2013) Xuezhu Zhang et al.   NEUROCHEMISTRY INTERNATIONAL

Adrenergic signaling and oxidative stress: a role for sirtuins?

(2013) Graziamaria Corbi et al.   Frontiers in Physiology

Effects of triptolide on the synaptophysin expression of hippocampal neurons in the AD cellular model

(2012) Jing Nie et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Triptolide and its expanding multiple pharmacological functions

(2011) Qiuyan Liu   INTERNATIONAL IMMUNOPHARMACOLOGY

Triptolide attenuate the oxidative stress induced by LPS/D-GalN in mice

(2011) Yan Lu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

RETRACTED: SIRT1 Suppresses β-Amyloid Production by Activating the α-Secretase Gene ADAM10

(2010) Gizem Donmez et al.   CELL

Genetic study between SIRT1, PPARD, PGC-1α genes and Alzheimer’s disease

(2008) S. Helisalmi et al.   JOURNAL OF NEUROLOGY

Triptolide protects podocytes from puromycin aminonucleoside induced injury in vivo and in vitro

(2008) Chun-Xia Zheng et al.   KIDNEY INTERNATIONAL