Structures of human ENT1 in complex with adenosine reuptake inhibitors

Role of Cysteine 416 in N -ethylmaleimide Sensitivity of Human Equilibrative Nucleoside Transporter 1 (hENT1)

(2018) Sylvia Y. M. Yao et al.   BIOCHEMICAL JOURNAL

Rapamycin-inspired macrocycles with new target specificity

(2018) Zufeng Guo et al.   Nature Chemistry

Visualizing multistep elevator-like transitions of a nucleoside transporter

(2017) Marscha Hirschi et al.   NATURE

X-ray structures and mechanism of the human serotonin transporter

(2016) Jonathan A. Coleman et al.   NATURE

Understanding transport by the major facilitator superfamily (MFS): structures pave the way

(2016) Esben M. Quistgaard et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Equilibrative nucleoside transporters—A review

(2016) Rebba C. Boswell-Casteel et al.   NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS

Adenosine as a Multi-Signalling Guardian Angel in Human Diseases: When, Where and How Does it Exert its Protective Effects?

(2016) Pier Andrea Borea et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Functional characterization of human equilibrative nucleoside transporter 1

(2016) Weiyun Huang et al.   Protein & Cell

Molecular basis of ligand recognition and transport by glucose transporters

(2015) Dong Deng et al.   NATURE

Structure and mechanism of the mammalian fructose transporter GLUT5

(2015) Norimichi Nomura et al.   NATURE

Energy coupling mechanisms of MFS transporters

(2015) Xuejun C. Zhang et al.   PROTEIN SCIENCE

Experimental phasing for structure determination using membrane-protein crystals grown by the lipid cubic phase method

(2015) Dianfan Li et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The Role of Flexible Loops in Folding, Trafficking and Activity of Equilibrative Nucleoside Transporters

(2015) Jaya Aseervatham et al.   PLoS One

Interdependence of Gemcitabine Treatment, Transporter Expression, and Resistance in Human Pancreatic Carcinoma Cells

(2015) Wolfgang Hagmann et al.   NEOPLASIA

Crystal structure of the human glucose transporter GLUT1

(2014) Dong Deng et al.   NATURE

Screening and large-scale expression of membrane proteins in mammalian cells for structural studies

(2014) April Goehring et al.   Nature Protocols

Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters

(2014) Zachary Lee Johnson et al.   eLife

Pancreatic Cancer hENT1 Expression and Survival From Gemcitabine in Patients From the ESPAC-3 Trial

(2013) William Greenhalf et al.   JNCI-Journal of the National Cancer Institute

The human concentrative and equilibrative nucleoside transporter families, SLC28 and SLC29

(2013) James D. Young et al.   MOLECULAR ASPECTS OF MEDICINE

X-ray structure of dopamine transporter elucidates antidepressant mechanism

(2013) Aravind Penmatsa et al.   NATURE

Crystal structure of a concentrative nucleoside transporter from Vibrio cholerae at 2.4 Å

(2012) Zachary Lee Johnson et al.   NATURE

X-ray structures of LeuT in substrate-free outward-open and apo inward-open states

(2012) Harini Krishnamurthy et al.   NATURE

iMOSFLM: a new graphical interface for diffraction-image processing withMOSFLM

(2011) T. Geoff G. Battye et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

REFMAC5 for the refinement of macromolecular crystal structures

(2011) Garib N. Murshudov et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Molecular predictors of gemcitabine response in pancreatic cancer

(2011) Ioannis A Voutsadakis   World Journal of Gastrointestinal Oncology

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Gemcitabine metabolic and transporter gene polymorphisms are associated with drug toxicity and efficacy in patients with locally advanced pancreatic cancer

(2010) Motofumi Tanaka et al.   CANCER

Human Equilibrative Nucleoside Transporter 1 and Human Concentrative Nucleoside Transporter 3 Predict Survival after Adjuvant Gemcitabine Therapy in Resected Pancreatic Adenocarcinoma

(2009) R. Marechal et al.   CLINICAL CANCER RESEARCH

Nucleoside Transporter Proteins

(2009) Miriam Molina-Arcas et al.   Current Vascular Pharmacology

Mutation of Trp29of human equilibrative nucleoside transporter 1 alters affinity for coronary vasodilator drugs and nucleoside selectivity

(2008) Robert J. Paproski et al.   BIOCHEMICAL JOURNAL

CoMFA and CoMSIA 3D-QSAR studies on S6-(4-nitrobenzyl)mercaptopurine riboside (NBMPR) analogs as inhibitors of human equilibrative nucleoside transporter 1 (hENT1)

(2008) Amol Gupte et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Human Equilibrative Nucleoside Transporter 1 Levels Predict Response to Gemcitabine in Patients With Pancreatic Cancer

(2008) James J. Farrell et al.   GASTROENTEROLOGY

A Competitive Inhibitor Traps LeuT in an Open-to-Out Conformation

(2008) S. K. Singh et al.   SCIENCE

Human equilibrative nucleoside transporter (ENT) family of nucleoside and nucleobase transporter proteins

(2008) J. D. Young et al.   XENOBIOTICA