Systems NMR: single-sample quantification of RNA, proteins and metabolites for biomolecular network analysis

RNA buffers the phase separation behavior of prion-like RNA binding proteins

(2018) Shovamayee Maharana et al.   SCIENCE

Protein Phase Separation: A New Phase in Cell Biology

(2018) Steven Boeynaems et al.   TRENDS IN CELL BIOLOGY

Rules of RNA specificity of hnRNP A1 revealed by global and quantitative analysis of its affinity distribution

(2017) Niyati Jain et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Binding to SMN2 pre-mRNA-protein complex elicits specificity for small molecule splicing modifiers

(2017) Manaswini Sivaramakrishnan et al.   Nature Communications

Pausing guides RNA folding to populate transiently stable RNA structures for riboswitch-based transcription regulation

(2017) Hannah Steinert et al.   eLife

BioNetGen 2.2: advances in rule-based modeling

(2016) Leonard A. Harris et al.   BIOINFORMATICS

Reaction monitoring using NMR

(2016) Michael A. Bernstein   MAGNETIC RESONANCE IN CHEMISTRY

Applications of NMR spectroscopy to systems biochemistry

(2016) Teresa W.-M. Fan et al.   PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

A Two-Way Street: Regulatory Interplay between RNA Polymerase and Nascent RNA Structure

(2016) Jinwei Zhang et al.   TRENDS IN BIOCHEMICAL SCIENCES

Post-translational modifications on yeast carbon metabolism: Regulatory mechanisms beyond transcriptional control

(2015) Farida Tripodi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Data2Dynamics: a modeling environment tailored to parameter estimation in dynamical systems: Fig. 1.

(2015) A. Raue et al.   BIOINFORMATICS

Real-time NMR monitoring of biological activities in complex physiological environments

(2015) Matthew J Smith et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Methyl groups as NMR probes for biomolecular interactions

(2015) Silke Wiesner et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

A Multiplexed NMR-Reporter Approach to Measure Cellular Kinase and Phosphatase Activities in Real-Time

(2015) Rossukon Thongwichian et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

NMR Insights into the Inner Workings of Living Cells

(2014) Mathilde H. Lerche et al.   ANALYTICAL CHEMISTRY

Cover Picture: Excellent Stability of a Lithium-Ion-Conducting Solid Electrolyte upon Reversible Li+/H+Exchange in Aqueous Solutions (Angew. Chem. Int. Ed. 1/2015)

(2014) Cheng Ma et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Live Cell NMR

(2014) Darón I. Freedberg et al.   Annual Review of Biophysics

Integrated RAS signaling defined by parallel NMR detection of effectors and regulators

(2014) Matthew J Smith et al.   Nature Chemical Biology

A sentinel protein assay for simultaneously quantifying cellular processes

(2014) Martin Soste et al.   NATURE METHODS

Characterization of the RNA recognition mode of hnRNP G extends its role in SMN2 splicing regulation

(2014) Ahmed Moursy et al.   NUCLEIC ACIDS RESEARCH

BioModels: ten-year anniversary

(2014) Vijayalakshmi Chelliah et al.   NUCLEIC ACIDS RESEARCH

NMR methods for structural studies of large monomeric and multimeric proteins

(2013) Dominique P Frueh et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Parameter uncertainty in biochemical models described by ordinary differential equations

(2013) J. Vanlier et al.   MATHEMATICAL BIOSCIENCES

The Utility of Paradoxical Components in Biological Circuits

(2013) Yuval Hart et al.   MOLECULAR CELL

An intronic structure enabled by a long-distance interaction serves as a novel target for splicing correction in spinal muscular atrophy

(2013) Natalia N. Singh et al.   NUCLEIC ACIDS RESEARCH

Isolated pseudo-RNA-recognition motifs of SR proteins can regulate splicing using a noncanonical mode of RNA recognition

(2013) A. Clery et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Using chemical shift perturbation to characterise ligand binding

(2013) Mike P. Williamson   PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

High-affinity interaction of hnRNP A1 with conserved RNA structural elements is required for translation and replication of enterovirus 71

(2013) Jeffrey D. Levengood et al.   RNA Biology

Rule-based modeling: a computational approach for studying biomolecular site dynamics in cell signaling systems

(2013) Lily A. Chylek et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

Rational Design of Allosteric Regulation of Homoserine Dehydrogenase by a Nonnatural Inhibitor l-Lysine

(2013) Zhen Chen et al.   ACS Synthetic Biology

Chain Length Determines the Folding Rates of RNA

(2012) Changbong Hyeon et al.   BIOPHYSICAL JOURNAL

Cell signaling, post-translational protein modifications and NMR spectroscopy

(2012) Francois-Xavier Theillet et al.   JOURNAL OF BIOMOLECULAR NMR

Solution structure of the two RNA recognition motifs of hnRNP A1 using segmental isotope labeling: how the relative orientation between RRMs influences the nucleic acid binding topology

(2012) Pierre Barraud et al.   JOURNAL OF BIOMOLECULAR NMR

Ordered Phosphorylation Events in Two Independent Cascades of the PTEN C-tail Revealed by NMR

(2012) Florence Cordier et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The structural stabilization of the κ three-way junction by Mg(II) represents the first step in the folding of a group II intron

(2012) Daniela Donghi et al.   NUCLEIC ACIDS RESEARCH

Mechanisms for differentiation between cognate and near-cognate ligands by purine riboswitches

(2012) Anna Wacker et al.   RNA Biology

Macromolecular NMR spectroscopy for the non-spectroscopist

(2011) Ann H. Kwan et al.   FEBS Journal

Macromolecular NMR spectroscopy for the non-spectroscopist: beyond macromolecular solution structure determination

(2011) Michael Bieri et al.   FEBS Journal

Prospects for Riboswitch Discovery and Analysis

(2011) Ronald R. Breaker   MOLECULAR CELL

Characterizing RNA dynamics at atomic resolution using solution-state NMR spectroscopy

(2011) Jameson R Bothe et al.   NATURE METHODS

Molecular basis of purine-rich RNA recognition by the human SR-like protein Tra2-β1

(2011) Antoine Cléry et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Automated Prediction of Protein Association Rate Constants

(2011) Sanbo Qin et al.   STRUCTURE

A Guide to Simple and Informative Binding Assays

(2010) Thomas D. Pollard   MOLECULAR BIOLOGY OF THE CELL

Direct observation of the temperature-induced melting process of the Salmonella fourU RNA thermometer at base-pair resolution

(2010) Jörg Rinnenthal et al.   NUCLEIC ACIDS RESEARCH

Real-time multidimensional NMR follows RNA folding with second resolution

(2010) M.-K. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-throughput serum NMR metabonomics for cost-effective holistic studies on systemic metabolism

(2009) Pasi Soininen et al.   ANALYST

Isotope labeling strategies for NMR studies of RNA

(2009) Kun Lu et al.   JOURNAL OF BIOMOLECULAR NMR

NMR spectroscopy brings invisible protein states into focus

(2009) Andrew J Baldwin et al.   Nature Chemical Biology

Time‐Resolved Dynamic Nuclear Polarization Enhanced NMR Spectroscopy

(2008) Sean Bowen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dynamical modeling and multi-experiment fitting with PottersWheel

(2008) Thomas Maiwald et al.   BIOINFORMATICS

Selected reaction monitoring for quantitative proteomics: a tutorial

(2008) Vinzenz Lange et al.   Molecular Systems Biology