CELA2A mutations predispose to early-onset atherosclerosis and metabolic syndrome and affect plasma insulin and platelet activation

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the KidneyNovelty and Significance

(2017) Louise V. Wain et al.   HYPERTENSION

Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk

(2017) Helen R Warren et al.   NATURE GENETICS

Inducing mitophagy in diabetic platelets protects against severe oxidative stress

(2016) Seung Hee Lee et al.   EMBO Molecular Medicine

Complex Formation of Human Proelastases with Procarboxypeptidases A1 and A2

(2016) András Szabó et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation

(2016) Thomas J Hoffmann et al.   NATURE GENETICS

Quantitative Proteomics Analysis of CaMKII Phosphorylation and the CaMKII Interactome in the Mouse Forebrain

(2015) Anthony J. Baucum et al.   ACS Chemical Neuroscience

The Combined Hyperlipidemia Caused by Impaired Wnt-LRP6 Signaling Is Reversed by Wnt3a Rescue

(2014) Gwang-woong Go et al.   Cell Metabolism

A Form of the Metabolic Syndrome Associated with Mutations in DYRK1B

(2014) Ali R. Keramati et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Type 2 Diabetes-Associated Gene Ide Is Required for Insulin Secretion and Suppression of  -Synuclein Levels in  -Cells

(2013) P. Steneberg et al.   DIABETES

Secretion of glucagon-like peptide-1 in patients with type 2 diabetes mellitus: systematic review and meta-analyses of clinical studies

(2013) S. Calanna et al.   DIABETOLOGIA

Impairment of GLP1-induced insulin secretion: role of genetic background, insulin resistance and hyperglycaemia

(2012) S. Herzberg-Schäfer et al.   DIABETES OBESITY & METABOLISM

Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase

(2012) Saswata Talukdar et al.   NATURE MEDICINE

P-selectin-dependent platelet aggregation and apoptosis may explain the decrease in platelet count during Helicobacter pylori infection

(2010) J.-J. Yeh et al.   BLOOD

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

Gene Expression Profiles of Beta-Cell Enriched Tissue Obtained by Laser Capture Microdissection from Subjects with Type 2 Diabetes

(2010) Lorella Marselli et al.   PLoS One