Structural basis for stereoselective dehydration and hydrogen-bonding catalysis by the SAM-dependent pericyclase LepI

Water-Mediated Carbon–Oxygen Hydrogen Bonding Facilitates S-Adenosylmethionine Recognition in the Reactivation Domain of Cobalamin-Dependent Methionine Synthase

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Structural basis of the Cope rearrangement and cyclization in hapalindole biogenesis

(2018) Sean A. Newmister et al.   Nature Chemical Biology

Unveiling sequential late-stage methyltransferase reactions in the meleagrin/oxaline biosynthetic pathway

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SAM-dependent enzyme-catalysed pericyclic reactions in natural product biosynthesis

(2017) Masao Ohashi et al.   NATURE

Structural insights into enzymatic [4+2]aza-cycloaddition in thiopeptide antibiotic biosynthesis

(2017) Dillon P. Cogan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Natural [4 + 2]-Cyclases

(2016) Byung-sun Jeon et al.   CHEMICAL REVIEWS

Recent advances of Diels–Alderases involved in natural product biosynthesis

(2016) Atsushi Minami et al.   JOURNAL OF ANTIBIOTICS

The Catalytic Mechanism of a Natural Diels–Alderase Revealed in Molecular Detail

(2016) Matthew J. Byrne et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Electrostatic catalysis of a Diels–Alder reaction

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Oriented electric fields as future smart reagents in chemistry

(2016) Sason Shaik et al.   Nature Chemistry

The structure of SpnF, a standalone enzyme that catalyzes [4 + 2] cycloaddition

(2015) Christopher D Fage et al.   Nature Chemical Biology

Electrostatic transition state stabilization rather than reactant destabilization provides the chemical basis for efficient chorismate mutase catalysis

(2014) Daniel Burschowsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impact of scaffold rigidity on the design and evolution of an artificial Diels-Alderase

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Conservation and Functional Importance of Carbon–Oxygen Hydrogen Bonding in AdoMet-Dependent Methyltransferases

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Architectures, mechanisms and molecular evolution of natural product methyltransferases

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Dali server: conservation mapping in 3D

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Roll: a new algorithm for the detection of protein pockets and cavities with a rolling probe sphere

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