Recent advances of Diels–Alderases involved in natural product biosynthesis

Dynamically Complex [6+4] and [4+2] Cycloadditions in the Biosynthesis of Spinosyn A

(2016) Ashay Patel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A new enzyme involved in the control of the stereochemistry in the decalin formation during equisetin biosynthesis

(2015) Naoki Kato et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Involvement of Lipocalin-like CghA in Decalin-Forming Stereoselective Intramolecular [4+2] Cycloaddition

(2015) Michio Sato et al.   CHEMBIOCHEM

Heterologous expression of highly reducing polyketide synthase involved in betaenone biosynthesis

(2015) Takahiro Ugai et al.   CHEMICAL COMMUNICATIONS

Natural Diels–Alderases: Elusive and Irresistable

(2015) Kimberly Klas et al.   JOURNAL OF ORGANIC CHEMISTRY

Chemoenzymatic Synthesis of Thiazolyl Peptide Natural Products Featuring an Enzyme-Catalyzed Formal [4 + 2] Cycloaddition

(2015) Walter J. Wever et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

In Vitro Biosynthesis of the Core Scaffold of the Thiopeptide Thiomuracin

(2015) Graham A. Hudson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Biosynthesis of Versipelostatin: Identification of an Enzyme-Catalyzed [4+2]-Cycloaddition Required for Macrocyclization of Spirotetronate-Containing Polyketides

(2015) Takuya Hashimoto et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The structure of SpnF, a standalone enzyme that catalyzes [4 + 2] cycloaddition

(2015) Christopher D Fage et al.   Nature Chemical Biology

An enzymatic [4+2] cyclization cascade creates the pentacyclic core of pyrroindomycins

(2015) Zhenhua Tian et al.   Nature Chemical Biology

Biosynthesis of the Tetramic Acids Sch210971 and Sch210972

(2015) Thomas B. Kakule et al.   ORGANIC LETTERS

Structure and mechanism of the tRNA-dependent lantibiotic dehydratase NisB

(2014) Manuel A. Ortega et al.   NATURE

Impact of scaffold rigidity on the design and evolution of an artificial Diels-Alderase

(2014) N. Preiswerk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Native Promoter Strategy for High-Yielding Synthesis and Engineering of Fungal Secondary Metabolites

(2014) Thomas B. Kakule et al.   ACS Synthetic Biology

Two Related Pyrrolidinedione Synthetase Loci in Fusarium heterosporum ATCC 74349 Produce Divergent Metabolites

(2013) Thomas B. Kakule et al.   ACS Chemical Biology

Current developments and challenges in the search for a naturally selected Diels-Alderase

(2012) Hak Joong Kim et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Generation of Thiocillin Ring Size Variants by Prepeptide Gene Replacement and in Vivo Processing by Bacillus cereus

(2012) Albert A. Bowers et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Fusarisetin A, an Acinar Morphogenesis Inhibitor from a Soil Fungus, Fusarium sp. FN080326

(2011) Jae-Hyuk Jang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Identification and engineering of the cytochalasin gene cluster from Aspergillus clavatus NRRL 1

(2011) Kangjian Qiao et al.   METABOLIC ENGINEERING

Enzyme-catalysed [4+2] cycloaddition is a key step in the biosynthesis of spinosyn A

(2011) Hak Joong Kim et al.   NATURE

Solanapyrone Synthase, a Possible Diels-Alderase and Iterative Type I Polyketide Synthase Encoded in a Biosynthetic Gene Cluster from Alternaria solani

(2010) Ken Kasahara  et al.   CHEMBIOCHEM

Thiazolyl Peptide Antibiotic Biosynthesis: A Cascade of Post-translational Modifications on Ribosomal Nascent Proteins

(2010) Christopher T. Walsh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Computational Design of an Enzyme Catalyst for a Stereoselective Bimolecular Diels-Alder Reaction

(2010) J. B. Siegel et al.   SCIENCE

Recent applications of intramolecular Diels–Alder reactions to natural product synthesis

(2009) Martin Juhl et al.   CHEMICAL SOCIETY REVIEWS

Complete Reconstitution of a Highly Reducing Iterative Polyketide Synthase

(2009) S. M. Ma et al.   SCIENCE

Cloning and Characterization of the Tetrocarcin A Gene Cluster from Micromonospora chalcea NRRL 11289 Reveals a Highly Conserved Strategy for Tetronate Biosynthesis in Spirotetronate Antibiotics

(2008) J. Fang et al.   JOURNAL OF BACTERIOLOGY