Incorporation of Putative Helix-Breaking Amino Acids in the Design of Novel Stapled Peptides: Exploring Biophysical and Cellular Permeability Properties
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Incorporation of Putative Helix-Breaking Amino Acids in the Design of Novel Stapled Peptides: Exploring Biophysical and Cellular Permeability Properties
Authors
Keywords
-
Journal
MOLECULES
Volume 24, Issue 12, Pages 2292
Publisher
MDPI AG
Online
2019-06-20
DOI
10.3390/molecules24122292
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Macrocyclic α helical peptide therapeutic modality: A perspective of learnings and challenges
- (2018) Tomi K. Sawyer et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Importance of Net Hydrophobicity in the Cellular Uptake of All-Hydrocarbon Stapled Peptides
- (2018) Koki Sakagami et al. MOLECULAR PHARMACEUTICS
- Dual inhibition of MDMX and MDM2 as a therapeutic strategy in leukemia
- (2018) Luis A. Carvajal et al. Science Translational Medicine
- Interactive comparison and remediation of collections of macromolecular structures
- (2017) Nigel W. Moriarty et al. PROTEIN SCIENCE
- Nanoparticles for the delivery of therapeutic antibodies: Dogma or promising strategy?
- (2016) Flávia Sousa et al. Expert Opinion on Drug Delivery
- Passive Membrane Permeability in Cyclic Peptomer Scaffolds Is Robust to Extensive Variation in Side Chain Functionality and Backbone Geometry
- (2016) Akihiro Furukawa et al. JOURNAL OF MEDICINAL CHEMISTRY
- Benzene Probes in Molecular Dynamics Simulations Reveal Novel Binding Sites for Ligand Design
- (2016) Yaw Sing Tan et al. Journal of Physical Chemistry Letters
- Biophysical determinants for cellular uptake of hydrocarbon-stapled peptide helices
- (2016) Gregory H Bird et al. Nature Chemical Biology
- ff14SB: Improving the Accuracy of Protein Side Chain and Backbone Parameters from ff99SB
- (2015) James A. Maier et al. Journal of Chemical Theory and Computation
- Small-Molecule Inhibitors of Protein-Protein Interactions: Progressing toward the Reality
- (2014) Michelle R. Arkin et al. CHEMISTRY & BIOLOGY
- A Membrane-Translocating Peptide Penetrates into Bilayers without Significant Bilayer Perturbations
- (2013) Juan Cruz et al. BIOPHYSICAL JOURNAL
- Hamiltonian replica-exchange simulations with adaptive biasing of peptide backbone and side chain dihedral angles
- (2013) Katja Ostermeir et al. JOURNAL OF COMPUTATIONAL CHEMISTRY
- Stapled α−helical peptide drug development: A potent dual inhibitor of MDM2 and MDMX for p53-dependent cancer therapy
- (2013) Yong S. Chang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Stapled Peptides with Improved Potency and Specificity That Activate p53
- (2012) Christopher J. Brown et al. ACS Chemical Biology
- JLigand: a graphical tool for theCCP4 template-restraint library
- (2012) Andrey A. Lebedev et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Overview of theCCP4 suite and current developments
- (2011) Martyn D. Winn et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Survey of the 2009 commercial optical biosensor literature
- (2011) Rebecca L. Rich et al. JOURNAL OF MOLECULAR RECOGNITION
- XDS
- (2010) Wolfgang Kabsch ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- A Stapled p53 Helix Overcomes HDMX-Mediated Suppression of p53
- (2010) Federico Bernal et al. CANCER CELL
- Synthetic therapeutic peptides: science and market
- (2009) Patrick Vlieghe et al. DRUG DISCOVERY TODAY
- Structural basis for high-affinity peptide inhibition of p53 interactions with MDM2 and MDMX
- (2009) M. Pazgier et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now