Stress-Induced Epigenetic Changes in Hippocampal Mkp-1 Promote Persistent Depressive Behaviors

Pioglitazone attenuates lipopolysaccharide-induced depression-like behaviors, modulates NF-κB/IL-6/STAT3, CREB/BDNF pathways and central serotonergic neurotransmission in mice

(2017) L. Liao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Local Interleukin-18 System in the Basolateral Amygdala Regulates Susceptibility to Chronic Stress

(2016) Tae-Kyung Kim et al.   MOLECULAR NEUROBIOLOGY

Exercise promotes the expression of brain derived neurotrophic factor (BDNF) through the action of the ketone body β-hydroxybutyrate

(2016) Sama F Sleiman et al.   eLife

A role for SUV39H1-mediated H3K9 trimethylation in the control of genome stability and senescence in WI38 human diploid lung fibroblasts

(2016) Corinne Sidler et al.   Aging-US

Rosemary tea consumption results to anxiolytic- and anti-depressant-like behavior of adult male mice and inhibits all cerebral area and liver cholinesterase activity; phytochemical investigation and in silico studies

(2015) Anastasia-Varvara Ferlemi et al.   CHEMICO-BIOLOGICAL INTERACTIONS

G9a-Mediated Regulation of OXT and AVP Expression in the Basolateral Amygdala Mediates Stress-Induced Lasting Behavioral Depression and Its Reversal by Exercise

(2015) Tae-Kyung Kim et al.   MOLECULAR NEUROBIOLOGY

Sound of silence: the properties and functions of repressive Lys methyltransferases

(2015) Chiara Mozzetta et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

TRH and TRH receptor system in the basolateral amygdala mediate stress-induced depression-like behaviors

(2015) Juli Choi et al.   NEUROPHARMACOLOGY

Rosmarinic Acid Alleviates Neurological Symptoms in the G93A-SOD1 Transgenic Mouse Model of Amyotrophic Lateral Sclerosis

(2015) Ji-Seon Seo et al.   Experimental Neurobiology

Therapeutic perspectives of epigenetically active nutrients

(2014) M Remely et al.   BRITISH JOURNAL OF PHARMACOLOGY

PPAR-γ Agonism as a Modulator of Mood: Proof-of-Concept for Pioglitazone in Bipolar Depression

(2014) David E. Kemp et al.   CNS DRUGS

A single allele of Hdac2 but not Hdac1 is sufficient for normal mouse brain development in the absence of its paralog

(2014) A. Hagelkruys et al.   DEVELOPMENT

Possible additional antidepressant-like mechanism of sodium butyrate: Targeting the hippocampus

(2014) Arum Han et al.   NEUROPHARMACOLOGY

Peroxisome proliferator-activated receptors and their ligands: nutritional and clinical implications - a review

(2014) Bogna Grygiel-Górniak   Nutrition Journal

Adenylyl cyclase-5 in the dorsal striatum function as a molecular switch for the generation of behavioral preferences for cue-directed food choices

(2014) Hannah Kim et al.   Molecular Brain

Involvement of Genetic and Environmental Factors in the Onset of Depression

(2014) Toshitaka Nabeshima et al.   Experimental Neurobiology

Implementation of a Two-dimensional Behavior Matrix to Distinguish Individuals with Differential Depression States in a Rodent Model of Depression

(2014) Jin-Young Park et al.   Experimental Neurobiology

Histone deacetylase isoforms regulate innate immune responses by deacetylating mitogen-activated protein kinase phosphatase-1

(2013) Y. Jeong et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Rosmarinic Acid Ameliorates Depressive-Like Behaviors in a Rat Model of CUS and Up-Regulates BDNF Levels in the Hippocampus and Hippocampal-Derived Astrocytes

(2013) Xiang Jin et al.   NEUROCHEMICAL RESEARCH

H3K9 and H3K14 acetylation co-occur at many gene regulatory elements, while H3K14ac marks a subset of inactive inducible promoters in mouse embryonic stem cells

(2012) Krishanpal Karmodiya et al.   BMC GENOMICS

Glucocorticoid receptor dimerization induces MKP1 to protect against TNF-induced inflammation

(2012) Sofie Vandevyver et al.   JOURNAL OF CLINICAL INVESTIGATION

NADPH Oxidase Mediates Depressive Behavior Induced by Chronic Stress in Mice

(2012) J.-S. Seo et al.   JOURNAL OF NEUROSCIENCE

An epigenetic blockade of cognitive functions in the neurodegenerating brain

(2012) Johannes Gräff et al.   NATURE

Epigenetic Mechanisms for the Early Environmental Regulation of Hippocampal Glucocorticoid Receptor Gene Expression in Rodents and Humans

(2012) Tie Yuan Zhang et al.   NEUROPSYCHOPHARMACOLOGY

Epigenetic Mechanisms of Depression and Antidepressant Action

(2011) Vincent Vialou et al.   Annual Review of Pharmacology and Toxicology

H3K9 methyltransferase G9a and the related molecule GLP

(2011) Y. Shinkai et al.   GENES & DEVELOPMENT

Epigenetic changes induced by curcumin and other natural compounds

(2011) Simone Reuter et al.   Genes and Nutrition

Rosmarinic acid and baicalin epigenetically derepress peroxisomal proliferator-activated receptor γ in hepatic stellate cells for their antifibrotic effect

(2011) Melissa D. Yang et al.   HEPATOLOGY

Hippocampal-dependent antidepressant-like activity of histone deacetylase inhibition

(2011) Herbert E. Covington et al.   NEUROSCIENCE LETTERS

Mitogen-Activated Protein Kinase Phosphatase-1 Negatively Regulates the Expression of Interleukin-6, Interleukin-8, and Cyclooxygenase-2 in A549 Human Lung Epithelial Cells

(2010) T. Turpeinen et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

A negative regulator of MAP kinase causes depressive behavior

(2010) Vanja Duric et al.   NATURE MEDICINE

The MAP kinase phosphatase MKP-1 regulates BDNF-induced axon branching

(2010) Freddy Jeanneteau et al.   NATURE NEUROSCIENCE

HDAC2 negatively regulates memory formation and synaptic plasticity

(2009) Ji-Song Guan et al.   NATURE

Rosmarinic Acid from Perillae Herba Produces an Antidepressant-Like Effect in Mice through Cell Proliferation in the Hippocampus

(2008) Naoki Ito et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Cyclic AMP inhibits JNK activation by CREB-mediated induction of c-FLIPL and MKP-1, thereby antagonizing UV-induced apoptosis

(2008) J Zhang et al.   CELL DEATH AND DIFFERENTIATION

Antioxidant activities of rosemary (Rosmarinus Officinalis L.) extract, blackseed (Nigella sativa L.) essential oil, carnosic acid, rosmarinic acid and sesamol

(2008) Naciye Erkan et al.   FOOD CHEMISTRY