miR-122 promotes hepatic lipogenesis via inhibiting the LKB1/AMPK pathway by targeting Sirt1 in non-alcoholic fatty liver disease

microRNA-130a suppresses breast cancer cell migration and invasion by targeting FOSL1 and upregulating ZO-1

(2018) Xiaowei Chen et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Plasma miR-17, miR-20a, miR-20b and miR-122 as potential biomarkers for diagnosis of NAFLD in type 2 diabetes mellitus patients

(2018) Dan Ye et al.   LIFE SCIENCES

miR-122 inhibition in a human liver organoid model leads to liver inflammation, necrosis, steatofibrosis and dysregulated insulin signaling

(2018) Hossein Sendi et al.   PLoS One

Decreased lipid metabolism but increased FA biosynthesis are coupled with changes in liver microRNAs in obese subjects with NAFLD

(2017) J Latorre et al.   INTERNATIONAL JOURNAL OF OBESITY

Inhibition of NAMPT aggravates high fat diet-induced hepatic steatosis in mice through regulating Sirt1/AMPKα/SREBP1 signaling pathway

(2017) Ling-Fang Wang et al.   Lipids in Health and Disease

Prevalence of nonalcoholic fatty liver disease in patients with type 2 diabetes mellitus

(2017) Wenjie Dai et al.   MEDICINE

Lipid accumulation product is a powerful tool to predict non-alcoholic fatty liver disease in Chinese adults

(2017) Haijiang Dai et al.   Nutrition & Metabolism

Analysis of association between circulating miR-122 and histopathological features of nonalcoholic fatty liver disease in patients free of hepatocellular carcinoma

(2016) Norio Akuta et al.   BMC GASTROENTEROLOGY

Deregulated hepatic microRNAs underlie the association between non-alcoholic fatty liver disease and coronary artery disease

(2016) Aitana Braza-Boïls et al.   LIVER INTERNATIONAL

Sirtuins and nonalcoholic fatty liver disease

(2016) Fatiha Nassir et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Differential TGFβ pathway targeting by miR-122 in humans and mice affects liver cancer metastasis

(2016) Shenyi Yin et al.   Nature Communications

Liver Fatty Acid Composition and Inflammation in Mice Fed with High-Carbohydrate Diet or High-Fat Diet

(2016) Lorena da Silva-Santi et al.   Nutrients

Altered microRNA-9 Expression Level is Directly Correlated with Pathogenesis of Nonalcoholic Fatty Liver Disease by Targeting Onecut2 and SIRT1

(2016) Ran Ao et al.   MEDICAL SCIENCE MONITOR

Lycium barbarum polysaccharide attenuates high-fat diet-induced hepatic steatosis by up-regulating SIRT1 expression and deacetylase activity

(2016) Li Jia et al.   Scientific Reports

Resveratrol restores the circadian rhythmic disorder of lipid metabolism induced by high-fat diet in mice

(2015) Linjie Sun et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Carbon monoxide protects against hepatic ischemia/reperfusion injury by modulating the miR-34a/SIRT1 pathway

(2015) Hyo Jeong Kim et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Longitudinal study of circulating miR-122 in a rat model of non-alcoholic fatty liver disease

(2015) Hiroya Yamada et al.   CLINICA CHIMICA ACTA

Recommendations for Diagnosis, Referral for Liver Biopsy, and Treatment of Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis

(2015) Erin K. Spengler et al.   MAYO CLINIC PROCEEDINGS

6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1–AMPK signalling

(2015) Ruiting Lin et al.   NATURE CELL BIOLOGY

LPSF/GQ-02 Inhibits the Development of Hepatic Steatosis and Inflammation in a Mouse Model of Non-Alcoholic Fatty Liver Disease (NAFLD)

(2015) Amanda Karolina Soares e Silva et al.   PLoS One

Green Tea Extract Rich in Epigallocatechin-3-Gallate Prevents Fatty Liver by AMPK Activation via LKB1 in Mice Fed a High-Fat Diet

(2015) Aline B. Santamarina et al.   PLoS One

Current pharmacological therapies for nonalcoholic fatty liver disease/nonalcoholic steatohepatitis

(2015) Yoshihisa Takahashi   WORLD JOURNAL OF GASTROENTEROLOGY

Isocaloric Pair-Fed High-Carbohydrate Diet Induced More Hepatic Steatosis and Inflammation than High-Fat Diet Mediated by miR-34a/SIRT1 Axis in Mice

(2015) Xinli Li et al.   Scientific Reports

Up Regulation of Liver-enriched Transcription Factors HNF4a and HNF6 and Liver-Specific MicroRNA (miR-122) by Inhibition of Let-7b in Mesenchymal Stem Cells

(2014) Effat Alizadeh et al.   Chemical Biology & Drug Design

Circulating microRNA signature in non-alcoholic fatty liver disease: from serum non-coding RNAs to liver histology and disease pathogenesis

(2014) Carlos J Pirola et al.   GUT

Inhibition of microRNA-24 expression in liver prevents hepatic lipid accumulation and hyperlipidemia

(2014) Raymond Ng et al.   HEPATOLOGY

LKB1 signalling attenuates early events of adipogenesis and responds to adipogenic cues

(2014) A. Gormand et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Ob/ob Mouse Livers Show Decreased Oxidative Phosphorylation Efficiencies and Anaerobic Capacities after Cold Ischemia

(2014) Michael J. J. Chu et al.   PLoS One

Effect on metabolic enzymes and thyroid receptors induced by BDE-47 by activation the pregnane X receptor in HepG2, a human hepatoma cell line

(2014) XinNan Hu et al.   TOXICOLOGY IN VITRO

MicroRNAs as controlled systems and controllers in non-alcoholic fatty liver disease

(2014) Nadia Panera   WORLD JOURNAL OF GASTROENTEROLOGY

Dual Role of MicroRNAs in NAFLD

(2013) Sara Ceccarelli et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Sirt1 Activation Ameliorates Renal Fibrosis by Inhibiting the TGF-β/Smad3 Pathway

(2013) Xin-Zhong Huang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Significance of serum and hepatic microRNA-122 levels in patients with non-alcoholic fatty liver disease

(2013) Hisamitsu Miyaaki et al.   LIVER INTERNATIONAL

SIRT1 and energy metabolism

(2012) X. Li   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

miR-34a/SIRT1/p53 is suppressed by ursodeoxycholic acid in the rat liver and activated by disease severity in human non-alcoholic fatty liver disease

(2012) Rui E. Castro et al.   JOURNAL OF HEPATOLOGY

MicroRNAs in metabolism and metabolic disorders

(2012) Veerle Rottiers et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer

(2010) Daniel Herranz et al.   Nature Communications

Hepatocyte-Specific Deletion of SIRT1 Alters Fatty Acid Metabolism and Results in Hepatic Steatosis and Inflammation

(2009) Aparna Purushotham et al.   Cell Metabolism

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

(2009) Carles Cantó et al.   NATURE

SIRT1 Modulation of the Acetylation Status, Cytosolic Localization, and Activity of LKB1

(2008) Fan Lan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY