miR-122 promotes hepatic lipogenesis via inhibiting the LKB1/AMPK pathway by targeting Sirt1 in non-alcoholic fatty liver disease
出版年份 2019 全文链接
标题
miR-122 promotes hepatic lipogenesis via inhibiting the LKB1/AMPK pathway by targeting Sirt1 in non-alcoholic fatty liver disease
作者
关键词
miR-122, Non-alcoholic fatty liver disease, Lipogenesis, Sirt1, AMPK pathway
出版物
MOLECULAR MEDICINE
Volume 25, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2019-06-13
DOI
10.1186/s10020-019-0085-2
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- microRNA-130a suppresses breast cancer cell migration and invasion by targeting FOSL1 and upregulating ZO-1
- (2018) Xiaowei Chen et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Plasma miR-17, miR-20a, miR-20b and miR-122 as potential biomarkers for diagnosis of NAFLD in type 2 diabetes mellitus patients
- (2018) Dan Ye et al. LIFE SCIENCES
- miR-122 inhibition in a human liver organoid model leads to liver inflammation, necrosis, steatofibrosis and dysregulated insulin signaling
- (2018) Hossein Sendi et al. PLoS One
- Decreased lipid metabolism but increased FA biosynthesis are coupled with changes in liver microRNAs in obese subjects with NAFLD
- (2017) J Latorre et al. INTERNATIONAL JOURNAL OF OBESITY
- Inhibition of NAMPT aggravates high fat diet-induced hepatic steatosis in mice through regulating Sirt1/AMPKα/SREBP1 signaling pathway
- (2017) Ling-Fang Wang et al. Lipids in Health and Disease
- Prevalence of nonalcoholic fatty liver disease in patients with type 2 diabetes mellitus
- (2017) Wenjie Dai et al. MEDICINE
- Lipid accumulation product is a powerful tool to predict non-alcoholic fatty liver disease in Chinese adults
- (2017) Haijiang Dai et al. Nutrition & Metabolism
- Analysis of association between circulating miR-122 and histopathological features of nonalcoholic fatty liver disease in patients free of hepatocellular carcinoma
- (2016) Norio Akuta et al. BMC GASTROENTEROLOGY
- Deregulated hepatic microRNAs underlie the association between non-alcoholic fatty liver disease and coronary artery disease
- (2016) Aitana Braza-Boïls et al. LIVER INTERNATIONAL
- Sirtuins and nonalcoholic fatty liver disease
- (2016) Fatiha Nassir et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Differential TGFβ pathway targeting by miR-122 in humans and mice affects liver cancer metastasis
- (2016) Shenyi Yin et al. Nature Communications
- Liver Fatty Acid Composition and Inflammation in Mice Fed with High-Carbohydrate Diet or High-Fat Diet
- (2016) Lorena da Silva-Santi et al. Nutrients
- Altered microRNA-9 Expression Level is Directly Correlated with Pathogenesis of Nonalcoholic Fatty Liver Disease by Targeting Onecut2 and SIRT1
- (2016) Ran Ao et al. MEDICAL SCIENCE MONITOR
- Lycium barbarum polysaccharide attenuates high-fat diet-induced hepatic steatosis by up-regulating SIRT1 expression and deacetylase activity
- (2016) Li Jia et al. Scientific Reports
- Resveratrol restores the circadian rhythmic disorder of lipid metabolism induced by high-fat diet in mice
- (2015) Linjie Sun et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Carbon monoxide protects against hepatic ischemia/reperfusion injury by modulating the miR-34a/SIRT1 pathway
- (2015) Hyo Jeong Kim et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Longitudinal study of circulating miR-122 in a rat model of non-alcoholic fatty liver disease
- (2015) Hiroya Yamada et al. CLINICA CHIMICA ACTA
- Recommendations for Diagnosis, Referral for Liver Biopsy, and Treatment of Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis
- (2015) Erin K. Spengler et al. MAYO CLINIC PROCEEDINGS
- 6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1–AMPK signalling
- (2015) Ruiting Lin et al. NATURE CELL BIOLOGY
- LPSF/GQ-02 Inhibits the Development of Hepatic Steatosis and Inflammation in a Mouse Model of Non-Alcoholic Fatty Liver Disease (NAFLD)
- (2015) Amanda Karolina Soares e Silva et al. PLoS One
- Green Tea Extract Rich in Epigallocatechin-3-Gallate Prevents Fatty Liver by AMPK Activation via LKB1 in Mice Fed a High-Fat Diet
- (2015) Aline B. Santamarina et al. PLoS One
- Current pharmacological therapies for nonalcoholic fatty liver disease/nonalcoholic steatohepatitis
- (2015) Yoshihisa Takahashi WORLD JOURNAL OF GASTROENTEROLOGY
- Isocaloric Pair-Fed High-Carbohydrate Diet Induced More Hepatic Steatosis and Inflammation than High-Fat Diet Mediated by miR-34a/SIRT1 Axis in Mice
- (2015) Xinli Li et al. Scientific Reports
- Up Regulation of Liver-enriched Transcription Factors HNF4a and HNF6 and Liver-Specific MicroRNA (miR-122) by Inhibition of Let-7b in Mesenchymal Stem Cells
- (2014) Effat Alizadeh et al. Chemical Biology & Drug Design
- Circulating microRNA signature in non-alcoholic fatty liver disease: from serum non-coding RNAs to liver histology and disease pathogenesis
- (2014) Carlos J Pirola et al. GUT
- Inhibition of microRNA-24 expression in liver prevents hepatic lipid accumulation and hyperlipidemia
- (2014) Raymond Ng et al. HEPATOLOGY
- LKB1 signalling attenuates early events of adipogenesis and responds to adipogenic cues
- (2014) A. Gormand et al. JOURNAL OF MOLECULAR ENDOCRINOLOGY
- Ob/ob Mouse Livers Show Decreased Oxidative Phosphorylation Efficiencies and Anaerobic Capacities after Cold Ischemia
- (2014) Michael J. J. Chu et al. PLoS One
- Effect on metabolic enzymes and thyroid receptors induced by BDE-47 by activation the pregnane X receptor in HepG2, a human hepatoma cell line
- (2014) XinNan Hu et al. TOXICOLOGY IN VITRO
- MicroRNAs as controlled systems and controllers in non-alcoholic fatty liver disease
- (2014) Nadia Panera WORLD JOURNAL OF GASTROENTEROLOGY
- Dual Role of MicroRNAs in NAFLD
- (2013) Sara Ceccarelli et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Sirt1 Activation Ameliorates Renal Fibrosis by Inhibiting the TGF-β/Smad3 Pathway
- (2013) Xin-Zhong Huang et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Significance of serum and hepatic microRNA-122 levels in patients with non-alcoholic fatty liver disease
- (2013) Hisamitsu Miyaaki et al. LIVER INTERNATIONAL
- SIRT1 and energy metabolism
- (2012) X. Li ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- miR-34a/SIRT1/p53 is suppressed by ursodeoxycholic acid in the rat liver and activated by disease severity in human non-alcoholic fatty liver disease
- (2012) Rui E. Castro et al. JOURNAL OF HEPATOLOGY
- MicroRNAs in metabolism and metabolic disorders
- (2012) Veerle Rottiers et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer
- (2010) Daniel Herranz et al. Nature Communications
- Hepatocyte-Specific Deletion of SIRT1 Alters Fatty Acid Metabolism and Results in Hepatic Steatosis and Inflammation
- (2009) Aparna Purushotham et al. Cell Metabolism
- AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
- (2009) Carles Cantó et al. NATURE
- SIRT1 Modulation of the Acetylation Status, Cytosolic Localization, and Activity of LKB1
- (2008) Fan Lan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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