MicroRNA-32 targeting PTEN enhances M2 macrophage polarization in the glioma microenvironment and further promotes the progression of glioma

Down-regulated paxillin suppresses cell proliferation and invasion by inhibiting M2 macrophage polarization in colon cancer

(2018) Ling-li Zhang et al.   BIOLOGICAL CHEMISTRY

PI3K/AKT signaling pathway involvement in fluoride-induced apoptosis in C2C12 cells

(2018) Bian-hua Zhou et al.   CHEMOSPHERE

Luteolin Regulates Macrophage Polarization via the PI3K/Akt Pathway to Inhibit the Apoptosis Stimulated by Angiotensin Ⅱ

(2018) Qiao Jiang et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Cardiac fibrosis: new insights into the pathogenesis

(2018) Zhen-Guo Ma et al.   International Journal of Biological Sciences

Primary brain tumours in adults

(2018) Sarah Lapointe et al.   LANCET

miR-21a negatively modulates tumor suppressor genes PTEN and miR-200c and further promotes the transformation of M2 macrophages

(2017) Ning Li et al.   IMMUNOLOGY AND CELL BIOLOGY

The role of PTEN in regulation of hepatic macrophages activation and function in progression and reversal of liver fibrosis

(2017) Yahui Cheng et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Tumour-associated macrophages secrete pleiotrophin to promote PTPRZ1 signalling in glioblastoma stem cells for tumour growth

(2017) Yu Shi et al.   Nature Communications

Expression site of P2RY12 in residential microglial cells in astrocytomas correlates with M1 and M2 marker expression and tumor grade

(2017) Changbin Zhu et al.   Acta Neuropathologica Communications

miR-92b regulates glioma cells proliferation, migration, invasion, and apoptosis via PTEN/Akt signaling pathway

(2016) Hang Song et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

The role of microglia and macrophages in glioma maintenance and progression

(2016) Dolores Hambardzumyan et al.   NATURE NEUROSCIENCE

CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2009–2013

(2016) Quinn T. Ostrom et al.   NEURO-ONCOLOGY

MicroRNA-106b promotes pituitary tumor cell proliferation and invasion through PI3K/AKT signaling pathway by targeting PTEN

(2016) Kai Zhou et al.   TUMOR BIOLOGY

miR-181a Induces Macrophage Polarized to M2 Phenotype and Promotes M2 Macrophage-mediated Tumor Cell Metastasis by Targeting KLF6 and C/EBPα

(2016) Jia Bi et al.   Molecular Therapy-Nucleic Acids

MiR-32 promotes gastric carcinoma tumorigenesis by targeting Kruppel-like factor 4

(2015) Chao Yan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

PTEN inhibits macrophage polarization from M1 to M2 through CCL2 and VEGF-A reduction and NHERF-1 synergism

(2015) Ning Li et al.   CANCER BIOLOGY & THERAPY

miR-603 promotes glioma cell growth via Wnt/β-catenin pathway by inhibiting WIF1 and CTNNBIP1

(2015) Mian Guo et al.   CANCER LETTERS

Periostin secreted by glioblastoma stem cells recruits M2 tumour-associated macrophages and promotes malignant growth

(2015) Wenchao Zhou et al.   NATURE CELL BIOLOGY

miR-106b is overexpressed in medulloblastomas and interacts directly with PTEN

(2015) Kay Ka-Wai Li et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Adenosine 2B Receptor Activation Reduces Myocardial Reperfusion Injury by Promoting Anti-Inflammatory Macrophages Differentiation via PI3K/Akt Pathway

(2015) Yikui Tian et al.   Oxidative Medicine and Cellular Longevity

HDAC inhibition prevents white matter injury by modulating microglia/macrophage polarization through the GSK3β/PTEN/Akt axis

(2015) Guohua Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Macrophages and cancer: from mechanisms to therapeutic implications

(2015) Renato Ostuni et al.   TRENDS IN IMMUNOLOGY

The expression of the PI3K/AKT/mTOR pathway in gastric cancer and its role in gastric cancer prognosis

(2015) Jieer Ying et al.   OncoTargets and Therapy

MicroRNA 21 Is a Homeostatic Regulator of Macrophage Polarization and Prevents Prostaglandin E2-Mediated M2 Generation

(2015) Zhuo Wang et al.   PLoS One

MiR-125a-3p Regulates Glioma Apoptosis and Invasion by Regulating Nrg1

(2015) Feng Yin et al.   PLoS One

miR-19a acts as an oncogenic microRNA and is up-regulated in bladder cancer

(2014) Yougang Feng et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Interferon-γ and celecoxib inhibit lung-tumor growth through modulating M2/M1 macrophage ratio in the tumor microenvironment

(2014) Lunxu Liu et al.   Drug Design Development and Therapy

MicroRNA-20b promotes cell growth of breast cancer cells partly via targeting phosphatase and tensin homologue (PTEN)

(2014) Weidong Zhou et al.   Cell and Bioscience

Glioma Grade Is Associated with the Accumulation and Activity of Cells Bearing M2 Monocyte Markers

(2013) M. Prosniak et al.   CLINICAL CANCER RESEARCH

MicroRNA-32 (miR-32) regulates phosphatase and tensin homologue (PTEN) expression and promotes growth, migration, and invasion in colorectal carcinoma cells

(2013) Weiyun Wu et al.   Molecular Cancer

CSF-1R inhibition alters macrophage polarization and blocks glioma progression

(2013) Stephanie M Pyonteck et al.   NATURE MEDICINE

Increase in tumor-associated macrophages after antiangiogenic therapy is associated with poor survival among patients with recurrent glioblastoma

(2013) C. Lu-Emerson et al.   NEURO-ONCOLOGY

MiR-200a impairs glioma cell growth, migration, and invasion by targeting SIM2-s

(2013) Yuhang Su et al.   NEUROREPORT

MicroRNA regulatory networks and human disease

(2012) Yin-Yuan Mo   CELLULAR AND MOLECULAR LIFE SCIENCES

Bufalin Induces Lung Cancer Cell Apoptosis via the Inhibition of PI3K/Akt Pathway

(2012) Zhitu Zhu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Androgen-regulated miR-32 targets BTG2 and is overexpressed in castration-resistant prostate cancer

(2012) S E Jalava et al.   ONCOGENE

PI3K/Akt is involved in bufalin-induced apoptosis in gastric cancer cells

(2008) Dan Li et al.   ANTI-CANCER DRUGS