Article
Polymer Science
Lena Vogt, Aldo R. Boccaccini
Summary: The study showed that electrospun cardiac patches made from a blend of poly(1,8-octanediol-co-citrate) (POC) and poly(epsilon-caprolactone) (PCL) exhibited promising mechanical properties and cytocompatibility for applications in cardiac tissue engineering (CTE). Further research is needed to explore their in vitro and in vivo potential.
EUROPEAN POLYMER JOURNAL
(2021)
Article
Materials Science, Textiles
Rezvan Mohamadinooripoor, Soheila Kashanian, Kobra Omidfar
Summary: Electrospun composite mats of PCL/PEE were used to fabricate PCL-PEE sutures with desirable mechanical and antibacterial properties. The sutures showed promising characteristics including sustained drug release, high tensile strength, antifungal effects, and accelerated wound healing.
FIBERS AND POLYMERS
(2023)
Review
Polymer Science
Sibusiso Alven, Blessing Atim Aderibigbe
Summary: The management of chronic wounds is challenging due to factors such as malnutrition, diseases, and bacterial infection. Wound dressings formulated from a combination of biopolymers and synthetic polymers show promising properties, especially when prepared using electrospinning technique.
Article
Chemistry, Multidisciplinary
Alena Opalkova Siskova, Maria Buckova, Zuzana Kronekova, Angela Kleinova, Stefan Nagy, Joanna Rydz, Andrej Opalek, Monika Slavikova, Anita Eckstein Andicsova
Summary: Nanofiber mats loaded with Diclofenac sodium salt on the base of poly(epsilon-caprolactone) were studied for their biocompatibility and ability to inhibit bacterial infections. The mats demonstrated good viability with human cells culture and showed significant activity against cancer cells. A minimal concentration of 12.5% was found to effectively eradicate both Gram-negative and Gram-positive bacteria.
Article
Polymer Science
Kemal Cetin
Summary: Poly(e-caprolactone)/polyethyleneimine nanofibers were fabricated and catalase was immobilized via coordination of Cu2+ ions, showing improved thermal and storage stability compared to free catalase. The immobilized nanofibers also demonstrated significant reusability.
JOURNAL OF APPLIED POLYMER SCIENCE
(2023)
Article
Engineering, Biomedical
Elisa Piatti, Marta Miola, Liliana Liverani, Enrica Verne, Aldo R. Boccaccini
Summary: In this study, composite electrospun fibers containing innovative bioactive glass nanoparticles were successfully produced and characterized. The retention of bioactive glass nanoparticles in the polymer matrix, the electrospinnability of the novel solution, and the properties of the obtained electrospun composites were extensively investigated. The results showed that the produced composite fibers exhibited biocompatibility, bioactivity, and overall properties suitable for tissue engineering applications.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
(2023)
Article
Materials Science, Paper & Wood
Melika Sharahi, Ahmad Hivechi, S. Hajir Bahrami, Nahid Hemmatinejad, Peiman B. Milan
Summary: This study produced nanoparticles from walnut shells and co-electrospun them with polycaprolactone and gelatin to create nanofibers with excellent mechanical properties. The nanofiber scaffolds showed excellent viability, growth, and proliferation of adipose-derived mesenchymal stem cells.
Article
Biochemistry & Molecular Biology
Vivekananthan Sadaiyandi, Raghavendra Ramalingam, Kantha Deivi Arunachalam, D. John Thiruvadigal
Summary: This study synthesized essential oil-loaded nanofiber mats from watermelon seed, jackfruit, and papaya using electrospinning technique. These mats exhibited mechanical competence, antibacterial activity, and biocompatibility, making them promising alternatives to conventional antibacterial wound dressings.
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
(2023)
Article
Materials Science, Multidisciplinary
Thannaphat Jenvoraphot, Boontharika Thapsukhon, Donraporn Daranarong, Robert Molloy, Chayarop Supanchart, Suttichai Krisanaprakornkit, Paul D. Topham, Brian Tighe, Anisa Mahomed, Winita Punyodom
Summary: In this research, a periodontal membrane with nanoporous structure and tetracycline drug loading was designed and fabricated to improve periodontal regeneration and anti-inflammatory effect.
ACS APPLIED POLYMER MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Eloy Rodriguez-deLeon, Moustapha Bah, Jose E. Baez, Maria T. Hernandez-Sierra, Karla J. Moreno, Alejandro Nunez-Vilchis, Jose Bonilla-Cruz, Kenneth J. Shea
Summary: In this study, three xanthophylls were used for the first time as initiators in the synthesis of sustainable xanthophyll-containing poly(epsilon-caprolactone). The obtained polyesters were characterized and evaluated for their use as additives in green lubricants. The results showed that xanthophylls-PCL exhibited better tribological behavior than current additives, indicating their potential as future commercial materials.
Article
Materials Science, Multidisciplinary
Xinghuan Lin, Shanshan Li, Yingfeng Wang, Xiaojian Yang, Joonhoo Jung, Zhiguang Li, Xuehong Ren, Yuyu Sun
Summary: This study developed biodegradable fibrous membranes with antibacterial properties by electrospinning, displaying significant antimicrobial efficacy against specific bacteria after surface treatment. The membranes also exhibited good thrombogenicity and hydrophobicity, suggesting potential for application in biomedical materials.
MATERIALS CHEMISTRY AND PHYSICS
(2021)
Article
Biophysics
Jingwen Wang, Jing Wang, Shuilai Qiu, Weijian Chen, Liang Cheng, Wenxiang Du, Jinghao Wang, Longfei Han, Lei Song, Yuan Hu
Summary: A black phosphorus-based biodegradable material with enhanced hydrophilicity, shape recovery, and osteodifferentiation properties was proposed in this study. By integrating amino black phosphorous into PLCL, the composite fibers showed excellent shape recovery and osteogenic capabilities, making them suitable for tissue engineering applications.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2022)
Article
Polymer Science
Rezvan Mohamadinooripoor, Soheila Kashanian, Pouran Moradipour, Soraya Sajadimajd, Elham Arkan, Ahmad Tajehmiri, Khodabakhsh Rashidi
Summary: By blending Propolis Ethanolic Extract with poly-E-caprolactone, elastomeric electrospun mats with therapeutic effects were prepared, showing good mechanical properties and accelerated wound healing ability, suitable for wound dressing and GTR membranes.
JOURNAL OF POLYMER RESEARCH
(2022)
Article
Cell & Tissue Engineering
Yulu Liu, Ya Liu, Zhiyuan Bai, Dongfang Wang, Yiyang Xu, Qian Li
Summary: In this study, PTFE nanofibrous membranes were electrospun and poly(epsilon-caprolactone) (PCL) shish-kebab microstructures were induced on the surface of PTFE nanofibers to improve biocompatibility and mechanical properties. The deposition of PCL lamella improved the hydrophilicity of the PTFE membrane, leading to enhanced cell proliferation and adhesion. The PTFE/PCL composite film also exhibited good anti-platelet adhesion properties due to the inertness of PTFE surface. Cell proliferation could be regulated by controlling the integrity of the PCL crystal network.
JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE
(2022)
Article
Chemistry, Inorganic & Nuclear
Wojciech Sas, Malgorzata Jasiurkowska-Delaporte, Pawel Czaja, Piotr Maciej Zielinski, Magdalena Fitta
Summary: This study synthesized electrospun nanofibres of PCL doped with 5 nm iron oxide nanoparticles, investigating their magnetic properties. Characterization of PCL-based composites was conducted using SEM, FTIR, and TGA, with a focus on analyzing the magnetic behavior of the material.
Article
Engineering, Biomedical
Maria Watroba, Wiktor Bednarczyk, Piotr K. Szewczyk, Jakub Kawalko, Krzysztof Mech, Alina Gruenewald, Irem Unalan, Nicola Taccardi, Gabriela Boelter, Manuel Banzhaf, Caroline Hain, Piotr Bala, Aldo R. Boccaccini
Summary: In vitro cytotoxicity assessment is crucial for the development of new biodegradable implant materials. Zinc has been reported to have excellent in vivo biocompatibility and its mechanical properties can be improved without degrading its biological response. This study investigated the impact of adding silver and magnesium to zinc on in vitro cytocompatibility and antibacterial properties. The results showed no significant differences between the tested zinc-based materials, and the highest LD50 of zinc ions was determined for the zinc-3Ag-0.5Mg alloy.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS
(2023)
Article
Biochemical Research Methods
Yesica R. Frontini-Lopez, Lautaro Rivera, Ana A. Aldana, Guadalupe Rivero, Liliana Liverani, Gustavo A. Abraham, Aldo R. Boccaccini, Diego M. Bustos, Marina Uhart
Summary: Human Adipose-Derived Mesenchymal Stem/Stromal Cells (hAD-MSCs) have great potential for tissue regeneration. Culturing these cells under hypoxic conditions improves their post-transplantation survival and regenerative performance. The combination of hAD-MSCs and PCL-nHA nanofibers enhances their osteoblast differentiation. This study reveals cellular adaptation to a three-dimensional environment, highlighting the suitability of PCL-nHA nanofibers for pre-conditioning hAD-MSCs.
BIOTECHNOLOGY JOURNAL
(2023)
Article
Biochemistry & Molecular Biology
Daniel A. Canales, Natalia Pinones, Marcela Saavedra, Carlos Loyo, Humberto Palza, Laura Peponi, Adrian Leones, Raul Vallejos Baier, Aldo R. Boccaccini, Alina Gruenelwald, Paula A. Zapata
Summary: This study developed electrospun scaffolds based on poly(L-lactic acid) (PLLA) with the addition of bioglass (n-BG) and zinc oxide (n-ZnO) nanoparticles, as well as a mixture of both, to create bifunctional biomaterials with enhanced bioactive and biocidal properties. The presence of n-BG increased fiber diameter, while ZnO did not significantly affect morphology. Mechanical properties decreased with nanoparticles. PLA/n-BG scaffolds promoted hydroxyapatite formation, which was inhibited by ZnO. Combining both nanoparticles reduced bacterial viability. The use of n-BG and n-ZnO fillers validated the development of bifunctional PLA-based scaffolds with bioactive and biocidal properties for bone tissue engineering.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Multidisciplinary
Josefina Ballarre, Daniel Buldain, Irem Unalan, Juan I. I. Pastore, Nora Mestorino, Aldo R. R. Boccaccini
Summary: Bioactive glasses with mesoporous structure have been developed for bone tissue engineering, providing high surface area for the release of bioactive ions and the loading of antibacterial drugs. In this study, mesoporous bioactive glass particles loaded with essential oil of Melaleuca armillaris and combined with gentamicin were investigated. The results showed that the particles exhibited strong bioactivity and antibacterial effect, but with different efficacy against different bacteria.
Review
Chemistry, Multidisciplinary
Matthias Hebisch, Stefanie Klostermeier, Katharina Wolf, Aldo R. Boccaccini, Stephan E. Wolf, Rudolph E. Tanzi, Doo Yeon Kim
Summary: Creating an accurate cellular model of Alzheimer's disease (AD) has been a long-standing challenge. Recent studies have shown that human AD neural cells integrated into a three-dimensional hydrogel matrix can replicate key features of AD neuropathology. The extracellular matrix (ECM) plays a critical role in determining the rate of neuropathogenesis in AD, and understanding how age-associated changes in the ECM affect disease pathology is important.
Article
Polymer Science
Matthaeus Davi Popov Pereira da Cunha, Alejandra Graciela Ponce, Gustavo Abel Abraham
Summary: Plant-derived proteins, especially soy protein isolate (SPI), have gained considerable attention in bionanotechnological applications due to their high availability, biodegradability, and biological properties. Electrospinning is a versatile technique for designing nanofibrous mats, but the water stability and sterilization of SPI mats needs improvement. In this study, oxidized sucrose was used as a green and low-cost crosslinker for electrospun SPI mats, resulting in bead-free and water-stable nanofibrous membranes. Sterilization by UV radiation was found to be effective for sterilizing the crosslinked SPI-based nanofibrous structures.
JOURNAL OF APPLIED POLYMER SCIENCE
(2023)
Article
Materials Science, Multidisciplinary
Hsuan-Heng Lu, Kai Zheng, Aldo R. Boccaccini, Liliana Liverani
Summary: Ce-doped calcium silicate-based bioactive glass sols were electrospun and heat-treated to form cotton-like fibrous structures. The 3D structures consisted of long and entangled fibers with interconnected pores, and the successful incorporation of Ce was confirmed by EDX analysis. The fibers exhibited high hydrophilicity and in vitro bioactivity in simulated body fluid. They showed no cytotoxicity to keratinocytes and did not hinder the wound closure process in vitro.
Article
Materials Science, Multidisciplinary
Lukasz Pawlowski, Muhammad Asim Akhtar, Andrzej Zielinski, Aldo R. Boccaccini
Summary: The aim of this study was to investigate the response of coatings composed of chitosan (CS), Eudragit E 100 (EE100), or poly(4-vinylpyridine) (P4VP) on a silver nanoparticle (AgNPs)-decorated titanium substrate when in contact with human osteoblast-like MG-63 cells. The biopolymer coatings were successfully deposited on the substrate with high uniformity, and the deposited silver did not exhibit cytotoxicity. The biological study showed that the CS/EE100 coating performed better than the CS/P4VP coating, with a decrease in MG-63 cell viability observed only after three days of testing.
Review
Engineering, Biomedical
Lisa Schoebel, Aldo R. Boccaccini
Summary: This review comprehensively summarizes recent research on glycosaminoglycan-modified electrically conductive polymers for biomedical applications. It discusses the effect of different biological dopants on material characteristics and summarizes the key findings of biological characterization in vitro and in vivo. The remaining challenges in the field are also discussed.
ACTA BIOMATERIALIA
(2023)
Article
Materials Science, Multidisciplinary
Slila Chayanun, Anahita Ahmadi Soufivand, Jessica Faber, Silvia Budday, Boonrat Lohwongwatana, Aldo R. Boccaccini
Summary: Cartilage tissue engineering is improved by adding nanofibrillated cellulose (NFC) to alginate dialdehyde-gelatin (ADA-GEL) hydrogel, resulting in increased stiffness of the composite hydrogel. The maximum compressive effective modulus is 19.6 kPa. Cell viability, proliferation, and chondrogenic differentiation of ATDC5 cells are evaluated using immunohistochemical staining. The potential application of an osteochondral plug with polyetheretherketone as the subchondral bone anchor part is proposed.
ADVANCED ENGINEERING MATERIALS
(2023)
Article
Biochemistry & Molecular Biology
Jessica Borges-Vilches, Irem Unalan, Claudio R. Aguayo, Katherina Fernandez, Aldo R. Boccaccini
Summary: Chitosan-based scaffolds loaded with Pinus radiata extract bark and grape seed extract were developed for wound dressing applications. The inclusion of these extracts improved the blood absorption ability, degradation rates, antibacterial activity, and cell viability of the scaffolds, making them suitable for wound dressing applications.
Article
Chemistry, Multidisciplinary
Abhishek Indurkar, Rajan Choudhary, Kristaps Rubenis, Mansingraj Nimbalkar, Anatolijs Sarakovskis, Aldo R. Boccaccini, Janis Locs
Summary: Amorphous calcium phosphate (ACP) and its derivatives containing carboxylic ions (ACPC) were synthesized and characterized for their physiochemical properties. A new synthesis approach was developed, and thorough analysis through various techniques revealed differences in the properties of ACP and ACPC. The cytocompatibility of the synthesized ACPs and ACPCs was evaluated, and ACPC synthesized with citrate showed the highest cell viability.
Article
Engineering, Biomedical
Zeqian Xu, Xuanyu Qi, Minyue Bao, Tian Zhou, Junfeng Shi, Zhiyan Xu, Mingliang Zhou, Aldo R. Boccaccini, Kai Zheng, Xinquan Jiang
Summary: Type II diabetes mellitus (TIIDM) poses challenges for dentists and orthopedists, but 3D-printed bioscaffolds containing Sr-MBGNs and GelMA can remodel the diabetic microenvironment, enhance bone regeneration, and promote osteogenic, angiogenic, and immunomodulatory properties through the release of Sr, Ca, and Si ions.
BIOACTIVE MATERIALS
(2023)
Article
Materials Science, Biomaterials
Ana Sonzogni, Guadalupe Rivero, Veronica Gonzalez, Gustavo Abraham, Marcelo Calderon, Roque Minari
Summary: This article presents a novel nano-in-nano platform for enteric protein delivery. The platform has pH-responsive properties, allowing it to protect proteins in the stomach and release them in the intestine. It also demonstrates versatility by allowing adjustment of fiber dissolution profiles.
BIOMATERIALS SCIENCE
(2023)
Article
Materials Science, Multidisciplinary
Deyong Zheng, Huihui Jin, Yucong Liao, Pengxia Ji
Summary: In this study, a highly stable and efficient catalyst, fluorine-doped Co3O4 (F-Co3O4), was developed for hydrogen production by water electrolysis. The F-Co3O4 catalyst exhibited a remarkable reduction in overpotential and demonstrated excellent stability for over 100 hours.
Article
Materials Science, Multidisciplinary
Ziwen Lv, Jintao Wang, Fengyi Wang, Jianqiang Wang, Fuquan Li, Hongtao Chen
Summary: Adding Cu6Sn5 nano particles can effectively inhibit the overgrowth of intermetallic compounds at the interfaces of solder joints in electronic devices, providing a solution to this issue. A new growth mechanism of intermetallic compounds at the interfaces was identified.
Article
Materials Science, Multidisciplinary
Jun Wang, Jiawei Chen, Wanru Liao, Fangyang Liu, Min Liu, Liangxing Jiang
Summary: A BiOI/AgI/Ag plasmonic heterostructure photocathode was successfully designed through electrodeposition, ion-exchange, and illumination methods. This photocathode exhibits superior performance in photoelectrochemical water splitting.
Article
Materials Science, Multidisciplinary
Xiaoxiao Liu, Xianxian Zhou, Xiaotao Ma, Qinbo Yuan, Shibin Liu
Summary: In this study, the authors propose a method to accelerate the reaction of polysulfides in lithium-sulfur batteries using a Ni@OC Mott-Schottky heterojunction as a catalyst. The experimental results demonstrate that the charge redistribution at the Ni@OC interface accelerates electron transfer and enhances catalytic activity, leading to improved reaction kinetics and battery performance.
Article
Materials Science, Multidisciplinary
Dayou Ma, Mohammad Rezasefat, Joziel Aparecido da Cruz, Sandro Campos Amico, Marco Giglio, Andrea Manes
Summary: The matrix has a significant effect on the impact resistance of composite materials. Replacing a brittle polymer with a more flexible one can improve impact resistance, but it poses challenges to standard testing methods. This study designs a new fixture for testing the low-velocity impact of soft composites and investigates the effect of the fixture on the mechanical performance.
Article
Materials Science, Multidisciplinary
Lingchang Wang, Qihang Yang, Huzhen Li, Ming Wei, Qian Wang, Zhenzhong Hu, Mengmeng Zhen
Summary: Bronze titanium dioxide (TiO2(B)) is a promising anode material for lithium-ion batteries due to its high specific capacity. However, its practical applications are hindered by poor conductivity and limited electrochemical kinetics. In this study, TiO2(B)-carbon nanosheets heterostructures are synthesized to enhance the cycling performance and rate capability of TiO2(B).
Article
Materials Science, Multidisciplinary
Atul Thakur, Ritesh Verma, Ankush Chauhan, Fayu Wan, Preeti Thakur
Summary: In this study, BaFe12O19 and BaFe12O19: Epoxy (50:50) nanocomposites were synthesized using the co-precipitation method. The structural information and material properties, such as crystallite size and electrical conductivity, were characterized by XRD, FESEM, EDX, and TEM techniques.
Article
Materials Science, Multidisciplinary
Jingyu Wu, Xinyan Ma, Yong Yang
Summary: A well-defined CoS2@NC(CS-500) hierarchical binder-free catalyst cathode is constructed through in-situ grown of ZIF-67 on carbon cloth and high-temperature carbonization. The cathode shows excellent reaction kinetics and electrochemical performance, providing inspiration for developing advanced Li-CO2 battery catalysts.
Article
Materials Science, Multidisciplinary
Svetlana M. Posokhova, Vladimir A. Morozov, Kirill N. Boldyrev, Dina Deyneko, Erzhena T. Pavlova, Bogdan I. Lazoryak
Summary: This study explores the impact of synthesis method and composition on the structure and luminescence properties of K5Eu1-xHox(MoO4)4 with the palmierite-type matrix. The co-doping of Eu3+ and Ho3+ ions plays a critical role in manipulating charge transfer and luminescence efficiency in the visible and infrared regions.
Article
Materials Science, Multidisciplinary
Jian Wang, Yeting Tao, Jingsheng Wang, Youtian Tao
Summary: A new electron-transport material iTPyBI-CN is developed through non-catalytic C-N coupling reaction. It exhibits better electroluminescence efficiency in organic light-emitting diodes compared to the commercial material TPBI, due to its twisted geometry and higher energy levels.
Article
Materials Science, Multidisciplinary
Tao Zhu, Feng Huang, Shuo Li, Yang Zhou
Summary: This article combines XRD analysis and microscopic structural observation to investigate the changes in limestone after high-temperature treatment. It finds that 500 degrees C is the critical temperature for crystalline and spatial arrangement changes in limestone, and the thermal conductivity, specific heat capacity, and heat storage coefficient gradually decrease after thermal treatment.
Article
Materials Science, Multidisciplinary
Muhammad Haekal Habibie, Fransiska Sri Herwahyu Krismastuti, Abdi Wira Septama, Faiza Maryani, Vivi Fauzia
Summary: This study focuses on the synthesis of zinc oxide nanostructure from zinc recovered from galvanization ash and highlights its potential as a sustainable source of zinc and as an antibacterial agent.
Article
Materials Science, Multidisciplinary
Jingyi Li, Yixin Xing, Wei Gu, Shousi Lu
Summary: In this study, PC@CaP microparticles were fabricated using biomimetic mineralization. The results showed that under environmental stress, PC@CaP exhibited improved stability and antioxidative activity, indicating its potential use in high-added value fields.
Article
Materials Science, Multidisciplinary
Yan Liu, Shunyou Chen
Summary: In this study, TNTs were used as a drug carrier and modified with ZIF-8 and silk fibroin to obtain a new drug loading platform. The results showed that this drug-loaded platform had a good drug release effect in vitro and could promote cell proliferation and osteogenic differentiation.
Article
Materials Science, Multidisciplinary
Chunhui Zhu, Wentao Wang, Qing Zhen, Xinning Huang, Shixin Li, Shaochang Wang, Xiaoping Ma, Xiaoxia Liu, Yalong Jiao, Kai Sun, Zhuangzhi Li, Huaixin Yang, Jianqi Li
Summary: A type of stacking fault is revealed in e-InSe crystal, which is associated with a small stacking-fault energy and shows exceptional plasticity.
