Marine Carotenoid Fucoxanthin Possesses Anti-Metastasis Activity: Molecular Evidence

Rat Glioma Cell-Based Functional Characterization of Anti-Stress and Protein Deaggregation Activities in the Marine Carotenoids, Astaxanthin and Fucoxanthin

(2019) Sajal Afzal et al.   Marine Drugs

Induction of Senescence in Cancer Cells by a Novel Combination of Cucurbitacin B and Withanone: Molecular Mechanism and Therapeutic Potential

(2019) Sukant Garg et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

The colorectal cancer epidemic: challenges and opportunities for primary, secondary and tertiary prevention

(2018) Hermann Brenner et al.   BRITISH JOURNAL OF CANCER

Pro-Apoptotic Activity of French Polynesian Padina pavonica Extract on Human Osteosarcoma Cells

(2018) Giulia Bernardini et al.   Marine Drugs

Identification and Functional Characterization of Anti-metastasis and Anti-angiogenic Activities of Triethylene Glycol Derivatives

(2018) Eonju Oh et al.   Frontiers in Oncology

Understanding the Effectiveness of Natural Compound Mixtures in Cancer through Their Molecular Mode of Action

(2017) Thazin Aung et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Relevance of mortalin to cancer cell stemness and cancer therapy

(2017) Chae-Ok Yun et al.   Scientific Reports

Stress Chaperone Mortalin Contributes to Epithelial-to-Mesenchymal Transition and Cancer Metastasis

(2016) Y. Na et al.   CANCER RESEARCH

Metastatic colonization by circulating tumour cells

(2016) Joan Massagué et al.   NATURE

Fucoxanthin: A Promising Medicinal and Nutritional Ingredient

(2015) Hui Zhang et al.   Evidence-based Complementary and Alternative Medicine

Functional Significance of Point Mutations in Stress Chaperone Mortalin and Their Relevance to Parkinson Disease

(2015) Renu Wadhwa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting Mortalin by Embelin Causes Activation of Tumor Suppressor p53 and Deactivation of Metastatic Signaling in Human Breast Cancer Cells

(2015) Nupur Nigam et al.   PLoS One

Fucoxanthin induces growth arrest and apoptosis in human bladder cancer T24 cells by up-regulation of p21 and down-regulation of mortalin

(2014) Linbo Wang et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Mortalin/GRP75 Binds to Complement C9 and Plays a Role in Resistance to Complement-dependent Cytotoxicity

(2014) Moran Saar Ray et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal structure of the nucleotide-binding domain of mortalin, the mitochondrial Hsp70 chaperone

(2014) Joseph Amick et al.   PROTEIN SCIENCE

Marine algal fucoxanthin inhibits the metastatic potential of cancer cells

(2013) Tae-Wook Chung et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Inhibition of mortalin expression reverses cisplatin resistance and attenuates growth of ovarian cancer cells

(2013) Ling Yang et al.   CANCER LETTERS

Effects of heating, aerial exposure and illumination on stability of fucoxanthin in canola oil

(2013) Dong Zhao et al.   FOOD CHEMISTRY

Fucoxanthin Enhances Cisplatin-Induced Cytotoxicity via NFκB-Mediated Pathway and Downregulates DNA Repair Gene Expression in Human Hepatoma HepG2 Cells

(2013) Cheng-Ling Liu et al.   Marine Drugs

Extensive Post-translational Modification of Active and Inactivated Forms of Endogenous p53

(2013) Caroline J. DeHart et al.   MOLECULAR & CELLULAR PROTEOMICS

Marine algal carotenoids inhibit angiogenesis by down-regulating FGF-2-mediated intracellular signals in vascular endothelial cells

(2013) Ponesakki Ganesan et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Cancer Preventive Efficacy of Marine Carotenoid Fucoxanthin: Cell Cycle Arrest and Apoptosis

(2013) Thamaraiselvan Rengarajan et al.   Nutrients

Dysfunction of the TP53 tumor suppressor gene in lymphoid malignancies

(2012) Z. Y. Xu-Monette et al.   BLOOD

Inhibition of tumor growth in vitro and in vivo by fucoxanthin against melanoma B16F10 cells

(2012) Kil-Nam Kim et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Mortalin–p53 interaction in cancer cells is stress dependent and constitutes a selective target for cancer therapy

(2011) W-J Lu et al.   CELL DEATH AND DIFFERENTIATION

Withanone binds to mortalin and abrogates mortalin–p53 complex: Computational and experimental evidence

(2011) Abhinav Grover et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Fucoxanthin and its deacetylated product, fucoxanthinol, induce apoptosis of primary effusion lymphomas

(2010) Kei Yamamoto et al.   CANCER LETTERS

Effects of fucoxanthin on proliferation and apoptosis in human gastric adenocarcinoma MGC-803 cells via JAK/STAT signal pathway

(2010) Rui-xue Yu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Fucoxanthin induces apoptosis in human leukemia HL-60 cells through a ROS-mediated Bcl-xL pathway

(2010) Kil-Nam Kim et al.   TOXICOLOGY IN VITRO

Implication of mitogen-activated protein kinase in the induction of G1 cell cycle arrest and gadd45 expression by the carotenoid fucoxanthin in human cancer cells

(2009) Yoshiko Satomi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Restoring p53 Function in Cancer: Novel Therapeutic Approaches for Applying the Brakes to Tumorigenesis

(2009) Alessandra Cintio et al.   Recent Patents on Anti-Cancer Drug Discovery

Antiadult T-cell leukemia effects of brown algae fucoxanthin and its deacetylated product, fucoxanthinol

(2008) Chie Ishikawa et al.   INTERNATIONAL JOURNAL OF CANCER