Plasma and tissue angiotensin-converting enzyme 2 activity and plasma equilibrium concentrations of angiotensin peptides in dogs with heart disease

A potential therapeutic role for angiotensin-converting enzyme 2 in human pulmonary arterial hypertension

(2018) Anna R. Hemnes et al.   EUROPEAN RESPIRATORY JOURNAL

The ACE2/Angiotensin-(1–7)/MAS Axis of the Renin-Angiotensin System: Focus on Angiotensin-(1–7)

(2018) Robson Augusto Souza Santos et al.   PHYSIOLOGICAL REVIEWS

Elevated plasma angiotensin converting enzyme 2 activity is an independent predictor of major adverse cardiac events in patients with obstructive coronary artery disease

(2018) Jay Ramchand et al.   PLoS One

Angiotensin-converting enzyme 2-Angiotensin 1-7/1-9 system: novel promising targets for heart failure treatment

(2017) Naim Kittana   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Roles of Angiotensin Peptides and Recombinant Human ACE2 in Heart Failure

(2017) Ratnadeep Basu et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Role of the ACE2/Angiotensin 1–7 Axis of the Renin–Angiotensin System in Heart Failure

(2016) Vaibhav B. Patel et al.   CIRCULATION RESEARCH

Targeting the Cardiac Myofibroblast Secretome to Treat Myocardial Fibrosis in Heart Failure

(2016) Karl T. Weber et al.   Circulation-Heart Failure

Circulating ACE2 activity correlates with cardiovascular disease development

(2016) K. Uri et al.   JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM

Effect of Pimobendan in Dogs with Preclinical Myxomatous Mitral Valve Disease and Cardiomegaly: The EPIC Study-A Randomized Clinical Trial

(2016) A. Boswood et al.   JOURNAL OF VETERINARY INTERNAL MEDICINE

Angiotensin-(1-5), an active mediator of renin-angiotensin system, stimulates ANP secretion via Mas receptor

(2016) Lamei Yu et al.   PEPTIDES

Angiotensin IV stimulates high atrial stretch-induced ANP secretion via insulin regulated aminopeptidase

(2015) Byung Mun Park et al.   PEPTIDES

Recent insights and therapeutic perspectives of angiotensin-(1–9) in the cardiovascular system

(2014) Maria Paz Ocaranza et al.   CLINICAL SCIENCE

Downregulation of the ACE2/Ang-(1–7)/Mas axis in transgenic mice overexpressing GH

(2014) Marina C Muñoz et al.   JOURNAL OF ENDOCRINOLOGY

Effects of the angiotensin-(1-7)/Mas/PI3K/Akt/nitric oxide axis and the possible role of atrial natriuretic peptide in an acute atrial tachycardia canine model

(2014) Jun Zhao et al.   JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM

Angiotensin-converting enzyme 2 and angiotensin 1–7: novel therapeutic targets

(2014) Fan Jiang et al.   Nature Reviews Cardiology

Molecular regulation of the renin–angiotensin system in haemodialysis patients

(2014) Johannes J. Kovarik et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Characterization of Angiotensin-Converting Enzyme 2 Ectodomain Shedding from Mouse Proximal Tubular Cells

(2014) Fengxia Xiao et al.   PLoS One

Multiple Functions of Angiotensin-Converting Enzyme 2 and Its Relevance in Cardiovascular Diseases

(2013) Keiji Kuba et al.   CIRCULATION JOURNAL

Pharmacokinetics and Pharmacodynamics of Recombinant Human Angiotensin-Converting Enzyme 2 in Healthy Human Subjects

(2013) Manuel Haschke et al.   CLINICAL PHARMACOKINETICS

Increasing Serum Soluble Angiotensin-Converting Enzyme 2 Activity After Intensive Medical Therapy Is Associated With Better Prognosis in Acute Decompensated Heart Failure

(2013) Zhili Shao et al.   JOURNAL OF CARDIAC FAILURE

Angiotensin II induced proteolytic cleavage of myocardial ACE2 is mediated by TACE/ADAM-17: A positive feedback mechanism in the RAS

(2013) Vaibhav B. Patel et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Intrarenal Distributions and Changes of Angiotensin-Converting Enzyme and Angiotensin-Converting Enzyme 2 in Feline and Canine Chronic Kidney Disease

(2013) Sawane MITANI et al.   JOURNAL OF VETERINARY MEDICAL SCIENCE

Angiotensin III: A physiological relevant peptide of the renin angiotensin system

(2013) Vudhya G. Yugandhar et al.   PEPTIDES

Targeting the ACE2 and Apelin Pathways Are Novel Therapies for Heart Failure: Opportunities and Challenges

(2012) Seyyed M. R. Kazemi-Bajestani et al.   Cardiology Research and Practice

Angiotensin IV protects against angiotensin II-induced cardiac injury via AT4 receptor

(2011) Hui Yang et al.   PEPTIDES

Targeting the ACE2–Ang-(1–7) pathway in cardiac fibroblasts to treat cardiac remodeling and heart failure

(2010) Michikado Iwata et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Angiotensin-(1–7) prevents atrial fibrosis and atrial fibrillation in long-term atrial tachycardia dogs

(2010) Enzhao Liu et al.   REGULATORY PEPTIDES

Ectodomain shedding of angiotensin converting enzyme 2 in human airway epithelia

(2009) Hong Peng Jia et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Soluble Angiotensin-Converting Enzyme 2 in Human Heart Failure: Relation With Myocardial Function and Clinical Outcomes

(2009) Slava Epelman et al.   JOURNAL OF CARDIAC FAILURE

Guidelines for the Diagnosis and Treatment of Canine Chronic Valvular Heart Disease

(2009) C. Atkins et al.   JOURNAL OF VETERINARY INTERNAL MEDICINE

Angiotensin II Up-Regulates Angiotensin I-Converting Enzyme (ACE), but Down-Regulates ACE2 via the AT1-ERK/p38 MAP Kinase Pathway

(2008) Vijay Koka et al.   AMERICAN JOURNAL OF PATHOLOGY

Detection of Soluble Angiotensin-Converting Enzyme 2 in Heart Failure

(2008) Slava Epelman et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY