Tumor-derived exosomes promote the in vitro osteotropism of melanoma cells by activating the SDF-1/CXCR4/CXCR7 axis

Horizontal transfer of exosomal CXCR4 promotes murine hepatocarcinoma cell migration, invasion and lymphangiogenesis

(2018) Min Li et al.   GENE

Cancer-secreted hsa-miR-940 induces an osteoblastic phenotype in the bone metastatic microenvironment via targeting ARHGAP1 and FAM134A

(2018) Kyoko Hashimoto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exosomes in melanoma: a role in tumor progression, metastasis and impaired immune system activity

(2018) Marco Tucci et al.   Oncotarget

Immune system and melanoma biology: a balance between immunosurveillance and immune escape

(2017) Anna Passarelli et al.   Oncotarget

pIL6-TRAIL-engineered umbilical cord mesenchymal/stromal stem cells are highly cytotoxic for myeloma cells both in vitro and in vivo

(2017) Paola Cafforio et al.   Stem Cell Research & Therapy

Serum exosomes as predictors of clinical response to ipilimumab in metastatic melanoma

(2017) Marco Tucci et al.   OncoImmunology

Melanoma cell–derived exosomes promote epithelial–mesenchymal transition in primary melanocytes through paracrine/autocrine signaling in the tumor microenvironment

(2016) Deyi Xiao et al.   CANCER LETTERS

Avβ3 integrin: Pathogenetic role in osteotropic tumors

(2015) Stefania Stucci et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

miRNAs in melanoma: a defined role in tumor progression and metastasis

(2015) Francesco Mannavola et al.   Expert Review of Clinical Immunology

Tumour exosome integrins determine organotropic metastasis

(2015) Ayuko Hoshino et al.   NATURE

CXCL12/CXCR4: a symbiotic bridge linking cancer cells and their stromal neighbors in oncogenic communication networks

(2015) F Guo et al.   ONCOGENE

Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines

(2015) Ikrame Lazar et al.   Pigment Cell & Melanoma Research

New therapeutic targets for cancer bone metastasis

(2015) Jing Y. Krzeszinski et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

The immune escape in melanoma: role of the impaired dendritic cell function

(2014) Marco Tucci et al.   Expert Review of Clinical Immunology

CXCL12–CXCR4 contributes to the implication of bone marrow in cancer metastasis

(2014) Jingsheng Shi et al.   Future Oncology

miRNA cargo within exosome-like vesicle transfer influences metastatic bone colonization

(2014) Karmele Valencia et al.   Molecular Oncology

The pre-metastatic niche: finding common ground

(2013) Jaclyn Sceneay et al.   CANCER AND METASTASIS REVIEWS

PTHrP Produced by Myeloma Plasma Cells Regulates Their Survival and Pro-Osteoclast Activity For Bone Disease Progression

(2013) Paola Cafforio et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Extracellular vesicles: Exosomes, microvesicles, and friends

(2013) Graça Raposo et al.   JOURNAL OF CELL BIOLOGY

A gene signature of bone metastatic colonization sensitizes for tumor-induced osteolysis and predicts survival in lung cancer

(2013) D Luis-Ravelo et al.   ONCOGENE

Xmrk-induced melanoma progression is affected by Sdf1 signals through Cxcr7

(2013) Daniel Liedtke et al.   Pigment Cell & Melanoma Research

Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

(2012) Héctor Peinado et al.   NATURE MEDICINE

Scavenging of CXCL12 by CXCR7 promotes tumor growth and metastasis of CXCR4-positive breast cancer cells

(2012) K E Luker et al.   ONCOGENE

Osteoblast-secreted factors enhance the expression of dysadherin and CCL2-dependent migration of renal carcinoma cells

(2011) Yvonne Schüler et al.   INTERNATIONAL JOURNAL OF CANCER

Carbon Monoxide Suppresses Membrane Expression of TLR4 via Myeloid Differentiation Factor-2 in  TC3 Cells

(2010) F. Rocuts et al.   JOURNAL OF IMMUNOLOGY

CXCR7 Functions as a Scavenger for CXCL12 and CXCL11

(2010) Ulrike Naumann et al.   PLoS One

Elucidation of CXCR7-Mediated Signaling Events and Inhibition of CXCR4-Mediated Tumor Cell Transendothelial Migration by CXCR7 Ligands

(2009) B. A. Zabel et al.   JOURNAL OF IMMUNOLOGY

 -arrestin- but not G protein-mediated signaling by the "decoy" receptor CXCR7

(2009) S. Rajagopal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Control of Chemokine-Guided Cell Migration by Ligand Sequestration

(2008) Bijan Boldajipour et al.   CELL

A role for leukemia inhibitory factor in melanoma-induced bone metastasis

(2008) Shigeaki Maruta et al.   CLINICAL & EXPERIMENTAL METASTASIS

Characterisation of breast cancer cell lines and establishment of a novel isogenic subclone to study migration, invasion and tumourigenicity

(2008) Linda Hughes et al.   CLINICAL & EXPERIMENTAL METASTASIS