Modulation of the NOP receptor signaling affects resilience to acute stress

Decreased Nociceptin Receptors Are Related to Resilience and Recovery in College Women Who Have Experienced Sexual Violence: Therapeutic Implications for Posttraumatic Stress Disorder

(2019) Rajesh Narendran et al.   BIOLOGICAL PSYCHIATRY

A review of the neurobiological underpinning of comorbid substance use and mood disorders

(2018) Nieves Gómez-Coronado et al.   JOURNAL OF AFFECTIVE DISORDERS

NOP agonists prevent the antidepressant-like effects of nortriptyline and fluoxetine but not R-ketamine

(2018) Victor A. D. Holanda et al.   PSYCHOPHARMACOLOGY

Nociceptin/orphanin FQ receptor agonists increase aggressiveness in the mouse resident-intruder test

(2018) Epifanio F. Silva et al.   BEHAVIOURAL BRAIN RESEARCH

Sex Differences in Risk and Resilience: Stress Effects on the Neural Substrates of Emotion and Motivation

(2018) Cara L. Wellman et al.   JOURNAL OF NEUROSCIENCE

Considering sex as a biological variable in preclinical research

(2017) Leah R. Miller et al.   FASEB JOURNAL

Effects of [Nphe1, Arg14, Lys15] N/OFQ-NH2 (UFP-101), a potent NOP receptor antagonist, on molecular, cellular and behavioural alterations associated with chronic mild stress

(2017) Giovanni Vitale et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Social defeat disrupts reward learning and potentiates striatal nociceptin/orphanin FQ mRNA in rats

(2017) Andre Der-Avakian et al.   PSYCHOPHARMACOLOGY

Genetic Deletion of the Nociceptin/Orphanin FQ Receptor in the Rat Confers Resilience to the Development of Drug Addiction

(2016) Marsida Kallupi et al.   NEUROPSYCHOPHARMACOLOGY

Antidepressant activity of nociceptin/orphanin FQ receptor antagonists in the mouse learned helplessness

(2016) Victor A. D. Holanda et al.   PSYCHOPHARMACOLOGY

A Selective Nociceptin Receptor Antagonist to Treat Depression: Evidence from Preclinical and Clinical Studies

(2015) Anke Post et al.   NEUROPSYCHOPHARMACOLOGY

Blockade of nociceptin/orphanin FQ receptor signaling reverses LPS-induced depressive-like behavior in mice

(2015) Iris U. Medeiros et al.   PEPTIDES

Immobility behavior during the forced swim test correlates with BNDF levels in the frontal cortex, but not with cognitive impairments

(2015) Milene Borsoi et al.   PHYSIOLOGY & BEHAVIOR

Nociceptin and the nociceptin receptor in learning and memory

(2015) Raül Andero   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Single housing during early adolescence causes time-, area- and peptide-specific alterations in endogenous opioids of rat brain

(2014) L Granholm et al.   BRITISH JOURNAL OF PHARMACOLOGY

Discovery of a Novel Series of Orally Active Nociceptin/Orphanin FQ (NOP) Receptor Antagonists Based on a Dihydrospiro(piperidine-4,7′-thieno[2,3-c]pyran) Scaffold

(2014) Miguel A. Toledo et al.   JOURNAL OF MEDICINAL CHEMISTRY

Restraint Stress Alters Nociceptin/Orphanin FQ and CRF Systems in the Rat Central Amygdala: Significance for Anxiety-Like Behaviors

(2014) R. Ciccocioppo et al.   JOURNAL OF NEUROSCIENCE

Learned helplessness: unique features and translational value of a cognitive depression model

(2013) Barbara Vollmayr et al.   CELL AND TISSUE RESEARCH

Nociceptin/orphanin FQ receptor antagonists as innovative antidepressant drugs

(2013) Elaine Cristina Gavioli et al.   PHARMACOLOGY & THERAPEUTICS

Role of Nociceptin/Orphanin FQ and NOP Receptors in the Response to Acute and Repeated Restraint Stress in Rats

(2012) G. Delaney et al.   JOURNAL OF NEUROENDOCRINOLOGY

Effect of stress on hippocampal nociceptin expression in the rat

(2012) Paola Nativio et al.   STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS

Animal research: Reporting in vivo experiments: The ARRIVE guidelines

(2010) Carol Kilkenny et al.   BRITISH JOURNAL OF PHARMACOLOGY

Nociceptin/orphanin FQ receptor knockout rats: In vitro and in vivo studies

(2010) Anna Rizzi et al.   NEUROPHARMACOLOGY

The nociceptin system and hippocampal cognition in mice A pharmacological and genetic analysis

(2009) Alexander Kuzmin et al.   BRAIN RESEARCH

Nociceptin/orphanin FQ and NOP receptor gene regulation after acute or repeated social defeat stress

(2009) Megan K. Green et al.   NEUROPEPTIDES

Chronic treatment with the selective NOP receptor antagonist [Nphe1,Arg14,Lys15]N/OFQ-NH2 (UFP-101) reverses the behavioural and biochemical effects of unpredictable chronic mild stress in rats

(2009) Giovanni Vitale et al.   PSYCHOPHARMACOLOGY

Pharmacological Characterization of the Newly Synthesized Nociceptin/Orphanin FQ–Receptor Agonist 1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-3-piperidinyl]-1H-benzimidazole as an Anxiolytic Agent

(2008) Akiko Hirao et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES