Children with type 1 diabetes of early age at onset – immune and metabolic phenotypes

Could ZnT8 antibodies replace ICA, GAD, IA2 and insulin antibodies in the diagnosis of type 1 diabetes?

(2018) A. Lounici Boudiaf et al.   Current Research in Translational Medicine

Innate immune activity as a predictor of persistent insulin secretion and association with responsiveness to CTLA4-Ig treatment in recent-onset type 1 diabetes

(2018) Susanne M. Cabrera et al.   DIABETOLOGIA

Differential Insulitic Profiles Determine the Extent of β-Cell Destruction and the Age at Onset of Type 1 Diabetes

(2016) Pia Leete et al.   DIABETES

Are Regulatory T Cells Defective in Type 1 Diabetes and Can We Fix Them?

(2016) Anabelle Visperas et al.   JOURNAL OF IMMUNOLOGY

Viral infections in type 1 diabetes mellitus — why the β cells?

(2016) Anne Op de Beeck et al.   Nature Reviews Endocrinology

CD4 T cell differentiation in type 1 diabetes

(2015) L. S. K. Walker et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Staging Presymptomatic Type 1 Diabetes: A Scientific Statement of JDRF, the Endocrine Society, and the American Diabetes Association

(2015) Richard A. Insel et al.   DIABETES CARE

Therapies to Preserve β-Cell Function in Type 1 Diabetes

(2015) Johnny Ludvigsson   DRUGS

Blood and Islet Phenotypes Indicate Immunological Heterogeneity in Type 1 Diabetes

(2014) Sefina Arif et al.   DIABETES

Humoral Autoimmunity in Type 1 Diabetes: Prediction, Significance, and Detection of Distinct Disease Subtypes

(2013) M. Pietropaolo et al.   Cold Spring Harbor Perspectives in Medicine

Low Frequency of Regulatory T Cells in the Peripheral Blood of Children with Type 1 Diabetes Diagnosed under the Age of Five

(2012) Agnieszka Szypowska et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Early seroconversion and rapidly increasing autoantibody concentrations predict prepubertal manifestation of type 1 diabetes in children at genetic risk

(2012) V. Parikka et al.   DIABETOLOGIA

Incidence trends for childhood type 1 diabetes in Europe during 1989–2003 and predicted new cases 2005–20: a multicentre prospective registration study

(2009) Christopher C Patterson et al.   LANCET

Causes of early-onset type 1 diabetes: toward data-driven environmental approaches

(2008) Pierre Bougnères et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Screening frequency for celiac disease and autoimmune thyroiditis in children and adolescents with type 1 diabetes mellitus - data from a German/Austrian multicentre survey

(2008) Elke E Fröhlich-Reiterer et al.   PEDIATRIC DIABETES

Extent of Beta Cell Destruction Is Important but Insufficient to Predict the Onset of Type 1 Diabetes Mellitus

(2008) David J. Klinke   PLoS One

CD 127−and FoxP3+Expression on CD25+CD4+T Regulatory Cells upon Specific Diabetogeneic Stimulation in High-risk Relatives of Type 1 Diabetes Mellitus Patients

(2008) Z. Vrabelova et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY