In vivo imaging of sterile microglial activation in rat brain after disrupting the blood-brain barrier with pulsed focused ultrasound: [18F]DPA-714 PET study

Blood-Brain Barrier Opening in Primary Brain Tumors with Non-invasive MR-Guided Focused Ultrasound: A Clinical Safety and Feasibility Study

(2019) Todd Mainprize et al.   Scientific Reports

Feedback control of microbubble cavitation for ultrasound-mediated blood–brain barrier disruption in non-human primates under magnetic resonance guidance

(2018) Hermes AS Kamimura et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Accelerated Clearance of Ultrasound Contrast Agents Containing Polyethylene Glycol is Associated with the Generation of Anti-Polyethylene Glycol Antibodies

(2018) Samantha M. Fix et al.   ULTRASOUND IN MEDICINE AND BIOLOGY

Blood–brain barrier opening in Alzheimer’s disease using MR-guided focused ultrasound

(2018) Nir Lipsman et al.   Nature Communications

Focused ultrasound with microbubbles induces sterile inflammatory response proportional to the blood brain barrier opening: Attention to experimental conditions

(2018) Zsofia I. Kovacs et al.   Theranostics

Reply to Kovacs et al.: Concerning acute inflammatory response following focused ultrasound and microbubbles in the brain

(2018) Dallan McMahon et al.   Theranostics

Focused Ultrasound-Induced Blood-Brain Barrier Opening Enhances GSK-3 Inhibitor Delivery for Amyloid-Beta Plaque Reduction

(2018) Po-Hung Hsu et al.   Scientific Reports

Time course of focused ultrasound effects on β-amyloid plaque pathology in the TgCRND8 mouse model of Alzheimer’s disease

(2018) Charissa T. Poon et al.   Scientific Reports

MRI and histological evaluation of pulsed focused ultrasound and microbubbles treatment effects in the brain

(2018) Zsofia I Kovacs et al.   Theranostics

Safe long-term repeated disruption of the blood-brain barrier using an implantable ultrasound device: a multiparametric study in a primate model

(2017) Catherine Horodyckid et al.   JOURNAL OF NEUROSURGERY

Blood-Brain Barrier Closure Time After Controlled Ultrasound-Induced Opening Is Independent of Opening Volume

(2017) Meaghan A. O'Reilly et al.   JOURNAL OF ULTRASOUND IN MEDICINE

Disrupting the blood–brain barrier with focused ultrasound: Perspectives on inflammation and regeneration

(2017) Joseph Silburt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reply to Silburt et al.: Concerning sterile inflammation following focused ultrasound and microbubbles in the brain

(2017) Zsofia I. Kovacs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Closed-loop control of targeted ultrasound drug delivery across the blood–brain/tumor barriers in a rat glioma model

(2017) Tao Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Effects of Oxygen on Ultrasound-Induced Blood–Brain Barrier Disruption in Mice

(2017) Nathan McDannold et al.   ULTRASOUND IN MEDICINE AND BIOLOGY

Acute Inflammatory Response Following Increased Blood-Brain Barrier Permeability Induced by Focused Ultrasound is Dependent on Microbubble Dose

(2017) Dallan McMahon et al.   Theranostics

Investigation of the Safety of Focused Ultrasound-Induced Blood-Brain Barrier Opening in a Natural Canine Model of Aging

(2017) Meaghan Anne O'Reilly et al.   Theranostics

The Translational Significance of the Neurovascular Unit

(2016) Heather L. McConnell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Imaging of Inflammation: Current Status

(2016) D. A. Hammoud   JOURNAL OF NUCLEAR MEDICINE

From blood–brain barrier to blood–brain interface: new opportunities for CNS drug delivery

(2016) William A. Banks   NATURE REVIEWS DRUG DISCOVERY

Disrupting the blood–brain barrier by focused ultrasound induces sterile inflammation

(2016) Zsofia I. Kovacs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Longitudinal Motor and Behavioral Assessment of Blood–Brain Barrier Opening with Transcranial Focused Ultrasound

(2016) Oluyemi O. Olumolade et al.   ULTRASOUND IN MEDICINE AND BIOLOGY

Focused Ultrasound-Induced Blood-Brain Barrier Opening: Association with Mechanical Index and Cavitation Index Analyzed by Dynamic Contrast-Enhanced Magnetic-Resonance Imaging

(2016) Po-Chun Chu et al.   Scientific Reports

Establishment and Dysfunction of the Blood-Brain Barrier

(2015) Zhen Zhao et al.   CELL

An overview of the influence of therapeutic ultrasound exposures on the vasculature: High intensity ultrasound and microbubble-mediated bioeffects

(2015) David E. Goertz   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Quantification of [18F]DPA-714 Binding in the Human Brain: Initial Studies in Healthy Controls and Alzheimer'S Disease Patients

(2015) Sandeep SV Golla et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Lack of neuroinflammation in the HIV-1 transgenic rat: an [18F]-DPA714 PET imaging study

(2015) Dianne E. Lee et al.   Journal of Neuroinflammation

Dealing with Danger in the CNS: The Response of the Immune System to Injury

(2015) Sachin P. Gadani et al.   NEURON

Scanning ultrasound removes amyloid-β and restores memory in an Alzheimer’s disease mouse model

(2015) Gerhard Leinenga et al.   Science Translational Medicine

Blood-Brain Barrier Opening in Behaving Non-Human Primates via Focused Ultrasound with Systemically Administered Microbubbles

(2015) Matthew E. Downs et al.   Scientific Reports

Drug delivery across the blood–brain barrier using focused ultrasound

(2014) Alison Burgess et al.   Expert Opinion on Drug Delivery

Alzheimer Disease in a Mouse Model: MR Imaging–guided Focused Ultrasound Targeted to the Hippocampus Opens the Blood-Brain Barrier and Improves Pathologic Abnormalities and Behavior

(2014) Alison Burgess et al.   RADIOLOGY

Studies of selective TNF inhibitors in the treatment of brain injury from stroke and trauma: a review of the evidence to date

(2014) Antonino Tuttolomondo et al.   Drug Design Development and Therapy

Could 18 F-DPA-714 PET imaging be interesting to use in the early post-stroke period?

(2014) Maria-Joao Ribeiro et al.   EJNMMI Research

Amyloid-β plaque reduction, endogenous antibody delivery and glial activation by brain-targeted, transcranial focused ultrasound

(2013) Jessica F. Jordão et al.   EXPERIMENTAL NEUROLOGY

Dependence of the reversibility of focused- ultrasound-induced blood-brain barrier opening on pressure and pulse length in vivo

(2013) Gesthimani Samiotaki et al.   IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL

Drug delivery to the brain by focused ultrasound induced blood–brain barrier disruption: Quantitative evaluation of enhanced permeability of cerebral vasculature using two-photon microscopy

(2013) Tam Nhan et al.   JOURNAL OF CONTROLLED RELEASE

The Translocator Protein Radioligand 18F-DPA-714 Monitors Antitumor Effect of Erufosine in a Rat 9L Intracranial Glioma Model

(2013) A. R. Awde et al.   JOURNAL OF NUCLEAR MEDICINE

Specific Imaging of Inflammation with the 18kDa Translocator Protein Ligand DPA-714 in Animal Models of Epilepsy and Stroke

(2013) Denise Harhausen et al.   PLoS One

Blood-Brain Barrier: Real-time Feedback-controlled Focused Ultrasound Disruption by Using an Acoustic Emissions–based Controller

(2012) Meaghan A. O’Reilly et al.   RADIOLOGY

[18F]DPA-714, [18F]PBR111 and [18F]FEDAA1106—Selective radioligands for imaging TSPO 18kDa with PET: Automated radiosynthesis on a TRACERLAb FX-FN synthesizer and quality controls

(2011) Bertrand Kuhnast et al.   APPLIED RADIATION AND ISOTOPES

Effect of anesthesia carrier gas on in vivo circulation times of ultrasound microbubble contrast agents in rats

(2011) Lee Mullin et al.   Contrast Media & Molecular Imaging

The Effect of Inhaled Gases on Ultrasound Contrast Agent Longevity In Vivo

(2011) Malak Itani et al.   MOLECULAR IMAGING AND BIOLOGY

Focused Ultrasound Surgery in Oncology: Overview and Principles

(2011) Clare M. C. Tempany et al.   RADIOLOGY

Reorganization of Gap Junctions after Focused Ultrasound Blood–Brain Barrier Opening in the Rat Brain

(2010) Angelika Alonso et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Reduced PBR/TSPO Expression After Minocycline Treatment in a Rat Model of Focal Cerebral Ischemia: A PET Study Using [18F]DPA-714

(2010) Abraham Martín et al.   MOLECULAR IMAGING AND BIOLOGY

In vivotranscranial cavitation threshold detection during ultrasound-induced blood–brain barrier opening in mice

(2010) Yao-Sheng Tung et al.   PHYSICS IN MEDICINE AND BIOLOGY

Strategies to advance translational research into brain barriers

(2008) Edward Neuwelt et al.   LANCET NEUROLOGY

Ultrasound Enhanced Delivery of Molecular Imaging and Therapeutic Agents in Alzheimer's Disease Mouse Models

(2008) Scott B. Raymond et al.   PLoS One

Progress and problems in the application of focused ultrasound for blood–brain barrier disruption

(2008) Natalia Vykhodtseva et al.   ULTRASONICS

Effects of Acoustic Parameters and Ultrasound Contrast Agent Dose on Focused-Ultrasound Induced Blood-Brain Barrier Disruption

(2008) Nathan McDannold et al.   ULTRASOUND IN MEDICINE AND BIOLOGY

Effect of Focused Ultrasound Applied With an Ultrasound Contrast Agent on the Tight Junctional Integrity of the Brain Microvascular Endothelium

(2008) Nickolai Sheikov et al.   ULTRASOUND IN MEDICINE AND BIOLOGY