Specific Imaging of Inflammation with the 18kDa Translocator Protein Ligand DPA-714 in Animal Models of Epilepsy and Stroke

The translocator protein ligand [18F]DPA-714 images glioma and activated microglia in vivo

(2012) Alexandra Winkeler et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Noninvasive Molecular Imaging of Neuroinflammation

(2012) Andreas H Jacobs et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Imaging Microglial/Macrophage Activation in Spinal Cords of Experimental Autoimmune Encephalomyelitis Rats by Positron Emission Tomography Using the Mitochondrial 18 kDa Translocator Protein Radioligand [18F]DPA-714

(2012) G. Abourbeh et al.   JOURNAL OF NEUROSCIENCE

Reactive Astrocytes Overexpress TSPO and Are Detected by TSPO Positron Emission Tomography Imaging

(2012) S. Lavisse et al.   JOURNAL OF NEUROSCIENCE

Targeted suppression of claudin-5 decreases cerebral oedema and improves cognitive outcome following traumatic brain injury

(2012) Matthew Campbell et al.   Nature Communications

The Translocator Protein

(2011) A. M. Scarf et al.   JOURNAL OF NUCLEAR MEDICINE

The immunology of stroke: from mechanisms to translation

(2011) Costantino Iadecola et al.   NATURE MEDICINE

Neuro-Intensive Care of Patients with Acute CNS Infections

(2011) J. David Beckham et al.   Neurotherapeutics

Initial evaluation in healthy humans of [18F]DPA-714, a potential PET biomarker for neuroinflammation

(2011) Nicolas Arlicot et al.   NUCLEAR MEDICINE AND BIOLOGY

Cytokines and innate inflammation in the pathogenesis of human traumatic brain injury

(2011) Adel Helmy et al.   PROGRESS IN NEUROBIOLOGY

Modeling Stroke in Mice - Middle Cerebral Artery Occlusion with the Filament Model

(2011) Odilo Engel et al.   Jove-Journal of Visualized Experiments

Kainic Acid-Induced Neurodegenerative Model: Potentials and Limitations

(2010) Xiang-Yu Zheng et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Reduced PBR/TSPO Expression After Minocycline Treatment in a Rat Model of Focal Cerebral Ischemia: A PET Study Using [18F]DPA-714

(2010) Abraham Martín et al.   MOLECULAR IMAGING AND BIOLOGY

Imaging of Microglia Activation in Stroke

(2010) Alexander Thiel et al.   STROKE

Evaluation of the PBR/TSPO Radioligand [18F]DPA-714 in a Rat Model of Focal Cerebral Ischemia

(2009) Abraham Martín et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

In Vivo Near-Infrared Fluorescence Imaging of Matrix Metalloproteinase Activity after Cerebral Ischemia

(2009) Jan Klohs et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Comparative Evaluation of the Translocator Protein Radioligands 11C-DPA-713, 18F-DPA-714, and 11C-PK11195 in a Rat Model of Acute Neuroinflammation

(2009) F. Chauveau et al.   JOURNAL OF NUCLEAR MEDICINE

[11C]-DPA-713 and [18F]-DPA-714 as New PET Tracers for TSPO: A Comparison with [11C]-(R)-PK11195 in a Rat Model of Herpes Encephalitis

(2009) Janine Doorduin et al.   MOLECULAR IMAGING AND BIOLOGY

Evaluation ofN-benzyl-N-[11C]methyl-2- (7-methyl-8-oxo-2-phenyl-7,8-dihydro-9H-purin-9-yl)acetamide ([11C]DAC) as a novel translocator protein (18 kDa) radioligand in kainic acid-lesioned rat

(2009) Kazuhiko Yanamoto et al.   SYNAPSE

DPA-714, a New Translocator Protein-Specific Ligand: Synthesis, Radiofluorination, and Pharmacologic Characterization

(2008) M. L. James et al.   JOURNAL OF NUCLEAR MEDICINE

Expression of the translocator protein of 18 kDa by microglia, macrophages and astrocytes based on immunohistochemical localization in abnormal human brain

(2008) M. Cosenza-Nashat et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Imaging of inflammation in the peripheral and central nervous system by magnetic resonance imaging

(2008) G. Stoll et al.   NEUROSCIENCE

Non-invasive visualization of CNS inflammation with nuclear and optical imaging

(2008) A. Wunder et al.   NEUROSCIENCE

Radiosynthesis and initial evaluation of [18F]-FEPPA for PET imaging of peripheral benzodiazepine receptors

(2008) Alan A. Wilson et al.   NUCLEAR MEDICINE AND BIOLOGY