Intranasal Delivery of lincRNA-Cox2 siRNA Loaded Extracellular Vesicles Decreases Lipopolysaccharide-Induced Microglial Proliferation in Mice

Milk exosomes - Natural nanoparticles for siRNA delivery

(2019) Farrukh Aqil et al.   CANCER LETTERS

PKH26 labeling of extracellular vesicles: Characterization and cellular internalization of contaminating PKH26 nanoparticles

(2018) Pia Pužar Dominkuš et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

lincRNA-Cox2 regulates NLRP3 inflammasome and autophagy mediated neuroinflammation

(2018) Zhenyi Xue et al.   CELL DEATH AND DIFFERENTIATION

Exosomal miR-9 Released from HIV Tat Stimulated Astrocytes Mediates Microglial Migration

(2018) Lu Yang et al.   Journal of Neuroimmune Pharmacology

Antiretroviral Drugs Alter the Content of Extracellular Vesicles from HIV-1-Infected Cells

(2018) Catherine DeMarino et al.   Scientific Reports

Ebola Virus VP40 Modulates Cell Cycle and Biogenesis of Extracellular Vesicles

(2018) Michelle L Pleet et al.   JOURNAL OF INFECTIOUS DISEASES

Astrocyte EV-induced lincRNA-Cox2 regulates microglial phagocytosis: Implications for morphine-mediated potentiation of neurodegeneration

(2018) Guoku Hu et al.   Molecular Therapy-Nucleic Acids

Genetic Models Reveal cis and trans Immune-Regulatory Activities for lincRNA-Cox2

(2018) Roland Elling et al.   Cell Reports

Coupled Proliferation and Apoptosis Maintain the Rapid Turnover of Microglia in the Adult Brain

(2017) Katharine Askew et al.   Cell Reports

Eliminating microglia in Alzheimer’s mice prevents neuronal loss without modulating amyloid-β pathology

(2016) Elizabeth E. Spangenberg et al.   BRAIN

LincRNA-Cox2 modulates TNF-α–induced transcription of Il12b gene in intestinal epithelial cells through regulation of Mi-2/NuRD-mediated epigenetic histone modifications

(2016) Qiang Tong et al.   FASEB JOURNAL

LincRNA-Cox2 Promotes Late Inflammatory Gene Transcription in Macrophages through Modulating SWI/SNF-Mediated Chromatin Remodeling

(2016) Guoku Hu et al.   JOURNAL OF IMMUNOLOGY

The role of microglia in human disease: therapeutic tool or target?

(2014) Nathalie Cartier et al.   ACTA NEUROPATHOLOGICA

An Evolutionarily Conserved Long Noncoding RNA TUNA Controls Pluripotency and Neural Lineage Commitment

(2014) Nianwei Lin et al.   MOLECULAR CELL

A Long Noncoding RNA Mediates Both Activation and Repression of Immune Response Genes

(2013) S. Carpenter et al.   SCIENCE

Release of Luminal Exosomes Contributes to TLR4-Mediated Epithelial Antimicrobial Defense

(2013) Guoku Hu et al.   PLoS Pathogens

Intranasal drug delivery: An efficient and non-invasive route for systemic administration

(2012) Stanislas Grassin-Delyle et al.   PHARMACOLOGY & THERAPEUTICS

Intranasal Exosomes for Treatment of Neuroinflammation?: Prospects and Limitations

(2011) Samira Lakhal et al.   MOLECULAR THERAPY

Treatment of Brain Inflammatory Diseases by Delivering Exosome Encapsulated Anti-inflammatory Drugs From the Nasal Region to the Brain

(2011) Xiaoying Zhuang et al.   MOLECULAR THERAPY

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

(2011) Lydia Alvarez-Erviti et al.   NATURE BIOTECHNOLOGY

SiRNA delivery with exosome nanoparticles

(2011) Jasper G van den Boorn et al.   NATURE BIOTECHNOLOGY

Physiology of Microglia

(2011) Helmut Kettenmann et al.   PHYSIOLOGICAL REVIEWS

Shedding microvesicles: artefacts no more

(2009) Emanuele Cocucci et al.   TRENDS IN CELL BIOLOGY

Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of β-secretase

(2008) Mohammad Ali Faghihi et al.   NATURE MEDICINE