Improvement of mesenchymal stromal cells and their derivatives for treating acute liver failure

Mesenchymal Stem Cell/Red Blood Cell-Inspired Nanoparticle Therapy in Mice with Carbon Tetrachloride-Induced Acute Liver Failure

(2018) Hongxia Liang et al.   ACS Nano

Therapeutic potential of Bama miniature pig adipose stem cells induced hepatocytes in a mouse model with acute liver failure

(2018) Shuang Zhang et al.   CYTOTECHNOLOGY

Acute-on-Chronic Liver Failure: Getting ready for prime-time

(2018) Jasmohan S Bajaj et al.   HEPATOLOGY

Bone marrow or adipose tissue mesenchymal stem cells: Comparison of the therapeutic potentials in mice model of acute liver failure

(2018) Hossein Zare et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Combination of MSC spheroids wrapped within autologous composite sheet dually protects against immune rejection and enhances stem cell transplantation efficacy

(2018) SangMin Kim et al.   TISSUE & CELL

Prostaglandin E2 secreted by mesenchymal stem cells protects against acute liver failure via enhancing hepatocyte proliferation

(2018) Yang Liu et al.   FASEB JOURNAL

A Novel Model to Predict 1-Month Risk of Transplant or Death in Hepatitis A-Related Acute Liver Failure

(2018) Jin Dong Kim et al.   HEPATOLOGY

AMSC-derived exosomes alleviate lipopolysaccharide/d-galactosamine-induced acute liver failure by miR-17-mediated reduction of TXNIP/NLRP3 inflammasome activation in macrophages

(2018) Yanning Liu et al.   EBioMedicine

Acute hepatitis E virus infection in patients with acute liver failure in China: Not quite an uncommon cause

(2017) Lin Wang et al.   HEPATOLOGY

Interleukin-10 secreted by mesenchymal stem cells attenuates acute liver failure through inhibiting pyroptosis

(2017) Jinglin Wang et al.   HEPATOLOGY RESEARCH

Mesenchymal stem cells attenuate acute liver injury by altering ratio between interleukin 17 producing and regulatory natural killer T cells

(2017) Neda Milosavljevic et al.   LIVER TRANSPLANTATION

Galectin-9 ameliorates fulminant liver injury

(2017) Tomoko Tadokoro et al.   Molecular Medicine Reports

hucMSC Exosome-Derived GPX1 Is Required for the Recovery of Hepatic Oxidant Injury

(2017) Yongmin Yan et al.   MOLECULAR THERAPY

Mesenchymal stem cells rescue acute hepatic failure by polarizing M2 macrophages

(2017) Yan-Wei Li et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Overexpression of c-Met in bone marrow mesenchymal stem cells improves their effectiveness in homing and repair of acute liver failure

(2017) Kun Wang et al.   Stem Cell Research & Therapy

Mesenchymal stem cells increase expression of heme oxygenase-1 leading to anti-inflammatory activity in treatment of acute liver failure

(2017) Zhi-heng Zhang et al.   Stem Cell Research & Therapy

Exosomes derived from human menstrual blood-derived stem cells alleviate fulminant hepatic failure

(2017) Lu Chen et al.   Stem Cell Research & Therapy

Attenuation of Postoperative Acute Liver Failure by Mesenchymal Stem Cell Treatment Due to Metabolic Implications

(2016) Hans-Michael Tautenhahn et al.   ANNALS OF SURGERY

Interleukin-10 Contributes to Therapeutic Effect of Mesenchymal Stem Cells for Acute Liver Failure via Signal Transducer and Activator of Transcription 3 Signaling Pathway

(2016) Xiao-Lei Shi et al.   CHINESE MEDICAL JOURNAL

Neutrophil Toll-Like Receptor 9 Expression and the Systemic Inflammatory Response in Acetaminophen-Induced Acute Liver Failure

(2016) Godhev K. Manakkat Vijay et al.   CRITICAL CARE MEDICINE

Quantitative evaluation of human bone mesenchymal stem cells rescuing fulminant hepatic failure in pigs

(2016) Dongyan Shi et al.   GUT

Intraportal mesenchymal stem cell transplantation prevents acute liver failure through promoting cell proliferation and inhibiting apoptosis

(2016) Jian-Feng Sang et al.   Hepatobiliary & Pancreatic Diseases International

Mesenchymal stem cells and their secreted molecules predominantly ameliorate fulminant hepatic failure and chronic liver fibrosis in mice respectively

(2016) Biao Huang et al.   Journal of Translational Medicine

Human umbilical cord-derived mesenchymal stem cells in acute liver injury: Hepatoprotective efficacy, subchronic toxicity, tumorigenicity, and biodistribution

(2016) Jun-Won Yun et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Effect of Secreted Molecules of Human Embryonic Stem Cell-Derived Mesenchymal Stem Cells on Acute Hepatic Failure Model

(2016) Majid Lotfinia et al.   STEM CELLS AND DEVELOPMENT

Transplantation of Adipose-Derived Mesenchymal Stem Cells Efficiently Rescues Thioacetamide-Induced Acute Liver Failure in Mice

(2016) L. Deng et al.   TRANSPLANTATION PROCEEDINGS

Combined treatment with MSC transplantation and neutrophil depletion ameliorates D-GalN/LPS-induced acute liver failure in rats

(2016) Xin Zhao et al.   Clinics and Research in Hepatology and Gastroenterology

Immunotolerant Properties of Mesenchymal Stem Cells: Updated Review

(2016) Whitney Faiella et al.   Stem Cells International

Useful properties of undifferentiated mesenchymal stromal cells and adipose tissue as the source in liver-regenerative therapy studied in an animal model of severe acute fulminant hepatitis

(2015) Bruna Maria Manzini et al.   CYTOTHERAPY

Mesenchymal stem cells from the human umbilical cord ameliorate fulminant hepatic failure and increase survival in mice

(2015) Jin-Feng Yang et al.   Hepatobiliary & Pancreatic Diseases International

Therapeutic Potential of Umbilical Cord Mesenchymal Stem Cells in Mice with Acute Hepatic Failure

(2015) Ting Feng et al.   INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS

Antioxidant treatment enhances human mesenchymal stem cell anti-stress ability and therapeutic efficacy in an acute liver failure model

(2015) Wen Zeng et al.   Scientific Reports

Adipose-derived stem cell-based treatment for acute liver failure

(2015) Guangfeng Chen et al.   Stem Cell Research & Therapy

C1q/TNF-related protein-3 (CTRP-3) attenuates lipopolysaccharide (LPS)-induced systemic inflammation and adipose tissue Erk-1/-2 phosphorylation in mice in vivo

(2014) Andreas Schmid et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Human umbilical cord mesenchymal stromal cells rescue mice from acetaminophen-induced acute liver failure

(2014) Zongcai Liu et al.   CYTOTHERAPY

Use of bone mesenchymal stem cells to treat rats with acute liver failure

(2014) S.F. Yuan et al.   GENETICS AND MOLECULAR RESEARCH

Bone mesenchymal stem cell transplantation via four routes for the treatment of acute liver failure in rats

(2014) LIHUA SUN et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

 -Galactosylceramide but Not Phenyl-Glycolipids Induced NKT Cell Anergy and IL-33-Mediated Myeloid-Derived Suppressor Cell Accumulation via Upregulation of egr2/3

(2014) J.-R. Huang et al.   JOURNAL OF IMMUNOLOGY

Systemic Treatment of Acute Liver Failure with Adipose Derived Stem Cells

(2014) Isabel Pascual-Miguelañez et al.   JOURNAL OF INVESTIGATIVE SURGERY

Cellular Therapy for Liver Disease

(2014) Robert C. Huebert et al.   MAYO CLINIC PROCEEDINGS

Up-regulation of CXCR4 in rat umbilical mesenchymal stem cells induced by serum from rat with acute liver failure promotes stem cells migration to injured liver tissue

(2014) Changqing Deng et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Human Umbilical Cord Mesenchymal Stem Cells and Derived Hepatocyte-Like Cells Exhibit Similar Therapeutic Effects on an Acute Liver Failure Mouse Model

(2014) Ruiping Zhou et al.   PLoS One

Concise Review: Therapeutic Potential of Mesenchymal Stem Cells for the Treatment of Acute Liver Failure and Cirrhosis

(2014) Vladislav Volarevic et al.   STEM CELLS

Targeted migration of mesenchymal stem cells modified with CXCR4 to acute failing liver improves liver regeneration

(2014) Hu-Cheng Ma   WORLD JOURNAL OF GASTROENTEROLOGY

Effect of bone marrow mesenchymal stem cell transplantation on acute hepatic failure in rats

(2014) SHUFANG YUAN et al.   Experimental and Therapeutic Medicine

Cell-based therapy for acute and chronic liver failures: Distinct diseases, different choices

(2014) Kai Sun et al.   Scientific Reports

Mesenchymal stem cell-derived exosomes promote hepatic regeneration in drug-induced liver injury models

(2014) Cheau Tan et al.   Stem Cell Research & Therapy

Administration of IL-1Ra Chitosan Nanoparticles Enhances the Therapeutic Efficacy of Mesenchymal Stem Cell Transplantation in Acute Liver Failure

(2013) Jiang-qiang Xiao et al.   ARCHIVES OF MEDICAL RESEARCH

Therapeutic Potential of Human Induced Pluripotent Stem Cell-Derived Mesenchymal Stem Cells in Mice with Lethal Fulminant Hepatic Failure

(2013) Mohsen Moslem et al.   CELL TRANSPLANTATION

A pilot study of autologous CD34-depleted bone marrow mononuclear cell transplantation via the hepatic artery in five patients with liver failure

(2013) Chung-Hwa Park et al.   CYTOTHERAPY

How important is differentiation in the therapeutic effect of mesenchymal stromal cells in liver disease?

(2013) Hanyu Wang et al.   CYTOTHERAPY

Mesenchymal stem cells alleviate bacteria-induced liver injury in mice by inducing regulatory dendritic cells

(2013) Yi Zhang et al.   HEPATOLOGY

Acute liver failure: Current trends

(2013) Faouzi Saliba et al.   JOURNAL OF HEPATOLOGY

Transplantation of mesenchymal stem cells for the treatment of liver diseases, is there enough evidence?

(2013) Raphael P.H. Meier et al.   Stem Cell Research

One cell, multiple roles: contribution of mesenchymal stem cells to tumor development in tumor microenvironment

(2013) Xue Yang et al.   Cell and Bioscience

Systematic review: acute liver failure - one disease, more than 40 definitions

(2012) K. A. Wlodzimirow et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Acquired Liver Injury in the Intensive Care Unit

(2012) Thomas Lescot et al.   ANESTHESIOLOGY

Therapeutic potential of transplanted placental mesenchymal stem cells in treating Chinese miniature pigs with acute liver failure

(2012) Hongcui Cao et al.   BMC Medicine

Effects of transplanted bone-marrow-derived mesenchymal stem cells in animal models of acute hepatitis

(2012) Xishan Zhu et al.   CELL AND TISSUE RESEARCH

Immediate intraportal transplantation of human bone marrow mesenchymal stem cells prevents death from fulminant hepatic failure in pigs

(2012) Jun Li et al.   HEPATOLOGY

Return of the Metabolic Trajectory to the Original Area after Human Bone Marrow Mesenchymal Stem Cell Transplantation for the Treatment of Fulminant Hepatic Failure

(2012) Jun Li et al.   JOURNAL OF PROTEOME RESEARCH

Amniotic-Fluid–Derived Mesenchymal Stem Cells Overexpressing Interleukin-1 Receptor Antagonist Improve Fulminant Hepatic Failure

(2012) Yu-Bao Zheng et al.   PLoS One

Infectious Complications of Acute and Chronic Liver Disease

(2012) Bettina Leber et al.   SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE

Human Umbilical Cord Matrix Stem Cells Efficiently Rescue Acute Liver Failure Through Paracrine Effects Rather than Hepatic Differentiation

(2012) Shichang Zhang et al.   TISSUE ENGINEERING PART A

Therapeutic potential of a distinct population of human amniotic fluid mesenchymal stem cells and their secreted molecules in mice with acute hepatic failure

(2011) Dimitra S Zagoura et al.   GUT

Coincidence of autoantibody production with the activation of natural killer T cells in α-galactosylceramide-mediated hepatic injury

(2011) Hiroaki Matsumoto et al.   IMMUNOLOGY

Hypoxic hepatitis

(2011) Jean Henrion   LIVER INTERNATIONAL

Hepatitis viruses: Not always what it seems to be

(2011) JUAN FERNANDO GALLEGOS-OROZCO et al.   REVISTA MEDICA DE CHILE

Transcriptional profiling and hepatogenic potential of acute hepatic failure-derived bone marrow mesenchymal stem cells

(2010) Jun Li et al.   DIFFERENTIATION

Drug-induced acute liver failure: Results of a U.S. multicenter, prospective study

(2010) Adrian Reuben et al.   HEPATOLOGY

Acute liver failure

(2010) William Bernal et al.   LANCET

Etiology and prognosis of fulminant hepatitis in adults

(2010) Philippe Ichai et al.   LIVER TRANSPLANTATION

The generation of hepatocytes from mesenchymal stem cells and engraftment into murine liver

(2010) Peggy Stock et al.   Nature Protocols

Impaired Liver Glucose Production in a Murine Model of Steatosis and Endotoxemia: Protection by Inducible Nitric Oxide Synthase

(2009) Oren Tirosh et al.   ANTIOXIDANTS & REDOX SIGNALING

Contribution of TIR domain-containing adapter inducing IFN-β-mediated IL-18 release to LPS-induced liver injury in mice

(2009) Michiko Imamura et al.   JOURNAL OF HEPATOLOGY

Eosinophils involved in fulminant hepatic failure are associated with high interleukin-6 expression and absence of interleukin-5 in liver and peripheral blood

(2009) Damião Carlos Moraes dos Santos et al.   LIVER INTERNATIONAL

Autophagy regulates lipid metabolism

(2009) Rajat Singh et al.   NATURE

Fibrogenic Potential of Human Multipotent Mesenchymal Stromal Cells in Injured Liver

(2009) Reto M. Baertschiger et al.   PLoS One

Long-Term Superior Performance of a Stem Cell/Hepatocyte Device for the Treatment of Acute Liver Failure

(2009) Hiroshi Yagi et al.   TISSUE ENGINEERING PART A

Stromal cell derived factor-1 enhances bone marrow mononuclear cell migration in mice with acute liver failure

(2009) Shi-Zhu Jin et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Hepatocyte differentiation of mesenchymal stem cells from human adipose tissue in vitro promotes hepatic integration in vivo

(2008) H Aurich et al.   GUT

Natural killer T cells regulate the homing of chemokine CXC receptor 3-positive regulatory T cells to the liver in mice

(2008) Tania Santodomingo-Garzon et al.   HEPATOLOGY

Rapid hepatic fate specification of adipose-derived stem cells and their therapeutic potential for liver failure

(2008) Agnieszka Banas et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Acute Liver Failure: Mechanisms of Hepatocyte Injury and Regeneration

(2008) Anna Rutherford et al.   SEMINARS IN LIVER DISEASE