Azithromycin Polarizes Macrophages to an M2 Phenotype via Inhibition of the STAT1 and NF-κB Signaling Pathways
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Title
Azithromycin Polarizes Macrophages to an M2 Phenotype via Inhibition of the STAT1 and NF-κB Signaling Pathways
Authors
Keywords
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Journal
JOURNAL OF IMMUNOLOGY
Volume 203, Issue 4, Pages 1021-1030
Publisher
The American Association of Immunologists
Online
2019-07-02
DOI
10.4049/jimmunol.1801228
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- The complexity of NF-κB signaling in inflammation and cancer
- (2013) Bastian Hoesel et al. Molecular Cancer
- Oxymatrine Prevents NF-κB Nuclear Translocation And Ameliorates Acute Intestinal Inflammation
- (2013) Javier Rivera Guzman et al. Scientific Reports
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- (2012) Dequan Xu et al. VIRUS RESEARCH
- Azithromycin distinctively modulates classical activation of human monocytes in vitro
- (2011) M Vrančić et al. BRITISH JOURNAL OF PHARMACOLOGY
- The effect of azithromycin on the maturation and function of murine bone marrow-derived dendritic cells
- (2011) S. Iwamoto et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Editorial: Switching on arginase in M2 macrophages
- (2011) Volker Briken et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Azithromycin May Inhibit Interleukin-8 Through Suppression of Rac1 and a Nuclear Factor-Kappa B Pathway in KB Cells Stimulated With Lipopolysaccharide
- (2011) Yusuke Matsumura et al. JOURNAL OF PERIODONTOLOGY
- Azithromycin Alters Macrophage Phenotype and Pulmonary Compartmentalization during Lung Infection with Pseudomonas
- (2010) D. J. Feola et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Inhibiting NF-κB activation by small molecules as a therapeutic strategy
- (2010) Subash C. Gupta et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- Non-canonical NF-κB signaling pathway
- (2010) Shao-Cong Sun CELL RESEARCH
- A single NFκB system for both canonical and non-canonical signaling
- (2010) Vincent Feng-Sheng Shih et al. CELL RESEARCH
- Mechanisms of Action and Clinical Application of Macrolides as Immunomodulatory Medications
- (2010) S. Kanoh et al. CLINICAL MICROBIOLOGY REVIEWS
- Modification of Cysteine 179 of IκBα Kinase by Nimbolide Leads to Down-regulation of NF-κB-regulated Cell Survival and Proliferative Proteins and Sensitization of Tumor Cells to Chemotherapeutic Agents
- (2010) Subash C. Gupta et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- STAT6−/− mice exhibit decreased cells with alternatively activated macrophage phenotypes and enhanced disease severity in murine neurocysticercosis
- (2010) Bibhuti B. Mishra et al. JOURNAL OF NEUROIMMUNOLOGY
- Specification of the NF-κB transcriptional response by p65 phosphorylation and TNF-induced nuclear translocation of IKKε
- (2010) Rita Moreno et al. NUCLEIC ACIDS RESEARCH
- Anti-inflammatory Activity of Azithromycin as Measured by Its NF-кB Inhibitory Activity
- (2010) Paul S. Cheung et al. OCULAR IMMUNOLOGY AND INFLAMMATION
- Nuclear Factor-Kappa B Inhibition Reduces Markedly Cell Proliferation in Epstein-Barr Virus-Infected Stomach Cancer, But Affects Variably in Epstein-Barr Virus-Negative Stomach Cancer
- (2009) Jin-Yong Jeong et al. CANCER INVESTIGATION
- Evidence for bioamplification of nine polychlorinated biphenyl (PCB) congeners in yellow perch (Perca flavascens) eggs during incubation
- (2009) Jennifer M. Daley et al. CHEMOSPHERE
- Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses
- (2009) T. H. Mogensen CLINICAL MICROBIOLOGY REVIEWS
- Prohibitin Inhibits Tumor Necrosis Factor alpha–induced Nuclear Factor-kappa B Nuclear Translocation via the Novel Mechanism of Decreasing Importin α3 Expression
- (2009) Arianne L. Theiss et al. MOLECULAR BIOLOGY OF THE CELL
- The NF- B Family of Transcription Factors and Its Regulation
- (2009) A. Oeckinghaus et al. Cold Spring Harbor Perspectives in Biology
- The IKK Complex, a Central Regulator of NF- B Activation
- (2009) A. Israel Cold Spring Harbor Perspectives in Biology
- Arginase-1–Expressing Macrophages Suppress Th2 Cytokine–Driven Inflammation and Fibrosis
- (2009) John T. Pesce et al. PLoS Pathogens
- Identification of PP2A as a crucial regulator of the NF-κB feedback loop: its inhibition by UVB turns NF-κB into a pro-apoptotic factor
- (2008) S Barisic et al. CELL DEATH AND DIFFERENTIATION
- Airway Inflammation in Cystic Fibrosis
- (2008) Arnon Elizur et al. CHEST
- IFNγ signaling—Does it mean JAK–STAT?
- (2008) Daniel J. Gough et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Azithromycin alters macrophage phenotype
- (2008) B. S. Murphy et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- An antiinflammatory role for IKKβ through the inhibition of “classical” macrophage activation
- (2008) Carol Ho Yan Fong et al. JOURNAL OF EXPERIMENTAL MEDICINE
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- (2008) Harm Maarsingh et al. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
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