Large oncosomes overexpressing integrin alpha-V promote prostate cancer adhesion and invasion via AKT activation

Extracellular vesicles in cancer — implications for future improvements in cancer care

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p53-dependent CD51 expression contributes to characteristics of cancer stem cells in prostate cancer

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Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

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Quantitative phase imaging unravels new insight into dynamics of mesenchymal and amoeboid cancer cell invasion

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The Crosstalk between Cancer Stem Cells and Microenvironment Is Critical for Solid Tumor Progression: The Significant Contribution of Extracellular Vesicles

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Extracellular Vesicles and Matrix Remodeling Enzymes: The Emerging Roles in Extracellular Matrix Remodeling, Progression of Diseases and Tissue Repair

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Targeting the cross-talk between Urokinase receptor and Formyl peptide receptor type 1 to prevent invasion and trans-endothelial migration of melanoma cells

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Protein and chemotherapy profiling of extracellular vesicles harvested from therapeutic induced senescent triple negative breast cancer cells

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Integrins and Exosomes, a Dangerous Liaison in Cancer Progression

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The αvβ6Integrin Is Transferred Intercellularly via Exosomes

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Activation of sonic hedgehog signaling enhances cell migration and invasion by induction of matrix metalloproteinase-2 and -9 via the phosphoinositide-3 kinase/AKT signaling pathway in glioblastoma

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Tumour exosome integrins determine organotropic metastasis

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Annexin A1 is involved in the acquisition and maintenance of a stem cell-like/aggressive phenotype in prostate cancer cells with acquired resistance to zoledronic acid

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Large oncosomes contain distinct protein cargo and represent a separate functional class of tumor-derived extracellular vesicles

(2015) Valentina R. Minciacchi et al.   Oncotarget

The receptor for urokinase-plasminogen activator (uPAR) controls plasticity of cancer cell movement in mesenchymal and amoeboid migration style

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Trading in your spindles for blebs: the amoeboid tumor cell phenotype in prostate cancer

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Integrin  v 6 Promotes an Osteolytic Program in Cancer Cells by Upregulating MMP2

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Large oncosomes mediate intercellular transfer of functional microRNA

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Targeting Activated Akt with GDC-0068, a Novel Selective Akt Inhibitor That Is Efficacious in Multiple Tumor Models

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Panobinostat synergizes with zoledronic acid in prostate cancer and multiple myeloma models by increasing ROS and modulating mevalonate and p38-MAPK pathways

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Acquired resistance to zoledronic acid and the parallel acquisition of an aggressive phenotype are mediated by p38-MAP kinase activation in prostate cancer cells

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Large Oncosomes in Human Prostate Cancer Tissues and in the Circulation of Mice with Metastatic Disease

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Akt1 mediates prostate cancer cell microinvasion and chemotaxis to metastatic stimuli via integrin β3 affinity modulation

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RhoA triggers a specific signaling pathway that generates transforming microvesicles in cancer cells

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The Urokinase-type Plasminogen Activator and the Generation of Inhibitors of Urokinase Activity and Signaling

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Oncosome Formation in Prostate Cancer: Association with a Region of Frequent Chromosomal Deletion in Metastatic Disease

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MMP-2 alters VEGF expression via αVβ3 integrin-mediated PI3K/AKT signaling in A549 lung cancer cells

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Urokinase Plasminogen Activator Receptor Choreographs Multiple Ligand Interactions: Implications for Tumor Progression and Therapy

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