A positive feedback between IDO1 metabolite and COL12A1 via MAPK pathway to promote gastric cancer metastasis

LncRNAs GIHCG and SPINT1-AS1 Are Crucial Factors for Pan-Cancer Cells Sensitivity to Lapatinib

(2019) Zhen Xiang et al.   Frontiers in Genetics

Molecular mechanism of Gd@C 82 (OH) 22 increasing collagen expression: Implication for encaging tumor

(2018) Jing Liu et al.   BIOMATERIALS

A new cancer immunotherapy via simultaneous DC-mobilization and DC-targeted IDO gene silencing using an immune-stimulatory nanosystem

(2018) Yujuan Zhang et al.   INTERNATIONAL JOURNAL OF CANCER

STAT3/p53 pathway activation disrupts IFN-β–induced dormancy in tumor-repopulating cells

(2018) Yuying Liu et al.   JOURNAL OF CLINICAL INVESTIGATION

Collagen IV-conveyed signals can regulate chemokine production and promote liver metastasis

(2018) George Vaniotis et al.   ONCOGENE

Somatostatin Receptor 2 signaling promotes growth and tumor survival in Small Cell Lung Cancer

(2018) Jonathan M. Lehman et al.   INTERNATIONAL JOURNAL OF CANCER

Cross-Database Analysis Reveals Sensitive Biomarkers for Combined Therapy for ERBB2+ Gastric Cancer

(2018) Zhen Xiang et al.   Frontiers in Pharmacology

Immune Checkpoint Inhibition Overcomes ADCP-Induced Immunosuppression by Macrophages

(2018) Shicheng Su et al.   CELL

Identification of discrepancy between CTLA4 expression and CTLA4 activation in gastric cancer

(2018) Zhen Xiang et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

A positive crosstalk between CXCR4 and CXCR2 promotes gastric cancer metastasis

(2017) Z Xiang et al.   ONCOGENE

Blockade of IDO-kynurenine-AhR metabolic circuitry abrogates IFN-γ-induced immunologic dormancy of tumor-repopulating cells

(2017) Yuying Liu et al.   Nature Communications

Kynurenine Modulates MMP-1 and Type-I Collagen Expression Via Aryl Hydrocarbon Receptor Activation in Dermal Fibroblasts

(2016) Malihe-Sadat Poormasjedi-Meibod et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Collagen-rich stroma in aggressive colon tumors induces mesenchymal gene expression and tumor cell invasion

(2016) T T Vellinga et al.   ONCOGENE

ZEB1 induces LOXL2-mediated collagen stabilization and deposition in the extracellular matrix to drive lung cancer invasion and metastasis

(2016) D H Peng et al.   ONCOGENE

miR-3188 regulates nasopharyngeal carcinoma proliferation and chemosensitivity through a FOXO1-modulated positive feedback loop with mTOR–p-PI3K/AKT-c-JUN

(2016) Mengyang Zhao et al.   Nature Communications

Increased expression of IDO associates with poor postoperative clinical outcome of patients with gastric adenocarcinoma

(2016) Hao Liu et al.   Scientific Reports

β-Arrestin1 enhances hepatocellular carcinogenesis through inflammation-mediated Akt signalling

(2015) Yidong Yang et al.   Nature Communications

1-Methyl-D-Tryptophan Potentiates TGF-β-Induced Epithelial-Mesenchymal Transition in T24 Human Bladder Cancer Cells

(2015) Rodrigo Barbosa Oliveira Brito et al.   PLoS One

IDO Downregulation Induces Sensitivity to Pemetrexed, Gemcitabine, FK866, and Methoxyamine in Human Cancer Cells

(2015) Saman Maleki Vareki et al.   PLoS One

Proteomic Signatures of the Desmoplastic Invasion Front Reveal Collagen Type XII as a Marker of Myofibroblastic Differentiation During Colorectal Cancer Metastasis

(2015) George S. Karagiannis et al.   Oncotarget

Prognostic implications of immunosuppressive protein expression in tumors as well as immune cell infiltration within the tumor microenvironment in gastric cancer

(2014) Jin Won Kim et al.   Gastric Cancer

Cryptic collagen IV promotes cell migration and adhesion in myeloid leukemia

(2014) Amanda J. Favreau et al.   Cancer Medicine

Connective tissue growth factor induces collagen I expression in human lung fibroblasts through the Rac1/MLK3/JNK/AP-1 pathway

(2013) Chien-Huang Lin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

High levels of type VII collagen expression in recessive dystrophic epidermolysis bullosa cutaneous squamous cell carcinoma keratinocytes increases PI3K and MAPK signalling, cell migration and invasion

(2013) C. Pourreyron et al.   BRITISH JOURNAL OF DERMATOLOGY

A Collagen-Remodeling Gene Signature Regulated by TGF-β Signaling Is Associated with Metastasis and Poor Survival in Serous Ovarian Cancer

(2013) Dong-Joo Cheon et al.   CLINICAL CANCER RESEARCH

The Correlation Between the Subsets of Tumor Infiltrating Memory T Cells and the Expression of Indoleamine 2,3-Dioxygenase in Gastric Cancer

(2013) Rupeng Zhang et al.   DIGESTIVE DISEASES AND SCIENCES

IDO1 Metabolites Activate β-catenin Signaling to Promote Cancer Cell Proliferation and Colon Tumorigenesis in Mice

(2013) Ameet I. Thaker et al.   GASTROENTEROLOGY

Mutations in the collagen XII gene define a new form of extracellular matrix-related myopathy

(2013) D. Hicks et al.   HUMAN MOLECULAR GENETICS

Kynurenine Increases Matrix Metalloproteinase-1 and -3 Expression in Cultured Dermal Fibroblasts and Improves Scarring In Vivo

(2013) Yunyuan Li et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

MiR-26b is down-regulated in carcinoma-associated fibroblasts from ER-positive breast cancers leading to enhanced cell migration and invasion

(2013) Eldo T Verghese et al.   JOURNAL OF PATHOLOGY

Enrichment map profiling of the cancer invasion front suggests regulation of colorectal cancer progression by the bone morphogenetic protein antagonist, gremlin-1

(2013) George S. Karagiannis et al.   Molecular Oncology

IKK epsilon kinase is crucial for viral G protein-coupled receptor tumorigenesis

(2013) Y. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer

(2013) C. Feig et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differences in Gastric Carcinoma Microenvironment Stratify According to EBV Infection Intensity: Implications for Possible Immune Adjuvant Therapy

(2013) Michael J. Strong et al.   PLoS Pathogens

Systemic Delivery of Salmonella typhimurium Transformed with IDO shRNA Enhances Intratumoral Vector Colonization and Suppresses Tumor Growth

(2012) C. A. Blache et al.   CANCER RESEARCH

Tryptophan Catabolism in Cancer: Beyond IDO and Tryptophan Depletion

(2012) M. Platten et al.   CANCER RESEARCH

Collagen/β1 integrin signaling up-regulates the ABCC1/MRP-1 transporter in an ERK/MAPK-dependent manner

(2012) Mohammed-Amine El Azreq et al.   MOLECULAR BIOLOGY OF THE CELL

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

(2012) Jordi Barretina et al.   NATURE

Three-dimensional collagen represses cyclin E1 via β1 integrin in invasive breast cancer cells

(2010) Yuehan Wu et al.   BREAST CANCER RESEARCH AND TREATMENT

Quantitative Secretome Analysis Reveals that COL6A1 is a Metastasis-Associated Protein Using Stacking Gel-Aided Purification Combined with iTRAQ Labeling

(2010) Kuo-Hsun Chiu et al.   JOURNAL OF PROTEOME RESEARCH

Hydroxyamidine Inhibitors of Indoleamine-2,3-dioxygenase Potently Suppress Systemic Tryptophan Catabolism and the Growth of IDO-Expressing Tumors

(2010) H. K. Koblish et al.   MOLECULAR CANCER THERAPEUTICS

Indoleamine 2,3-dioxygenase in T-cell tolerance and tumoral immune escape

(2008) Jessica B. Katz et al.   IMMUNOLOGICAL REVIEWS