RUNX1 promotes tumour metastasis by activating the Wnt/β-catenin signalling pathway and EMT in colorectal cancer

SULT2B1b promotes epithelial-mesenchymal transition through activation of the β-catenin/MMP7 pathway in hepatocytes

(2019) Xiaoming Yang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

LINC01354 interacting with hnRNP-D contributes to the proliferation and metastasis in colorectal cancer through activating Wnt/β-catenin signaling pathway

(2019) Jing Li et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

CAFs secreted exosomes promote metastasis and chemotherapy resistance by enhancing cell stemness and epithelial-mesenchymal transition in colorectal cancer

(2019) J. L. Hu et al.   Molecular Cancer

SLFN5 suppresses cancer cell migration and invasion by inhibiting MT1-MMP expression via AKT/GSK-3β/β-catenin pathway

(2019) Guoqing Wan et al.   CELLULAR SIGNALLING

Elevated hydrostatic pressure promotes ameloblastoma cell invasion through up-regulation of MMP-2 and MMP-9 expression via Wnt/β-catenin signalling

(2018) Zinan Yang et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

RUNX1 positively regulates the ErbB2/HER2 signaling pathway through modulating SOS1 expression in gastric cancer cells

(2018) Yoshihide Mitsuda et al.   Scientific Reports

Influence of TS (rs34743033) and RUNX1 (rs2014300) gene polymorphisms on survival outcomes of fluorouracil-based chemotherapy in Chinese advanced gastric cancer patients

(2018) Rongbo Han et al.   Cancer Management and Research

Suppression of Breast Cancer Stem Cells and Tumor Growth by the RUNX1 Transcription Factor

(2018) Deli Hong et al.   MOLECULAR CANCER RESEARCH

Interplay between transcription regulators RUNX1 and FUBP1 activates an enhancer of the oncogene c-KIT and amplifies cell proliferation

(2018) Lydie Debaize et al.   NUCLEIC ACIDS RESEARCH

Runx1 regulates osteogenic differentiation of BMSCs by inhibiting adipogenesis through Wnt/β-catenin pathway

(2018) Yuan Luo et al.   ARCHIVES OF ORAL BIOLOGY

FOXP3 promotes tumor growth and metastasis by activating Wnt/β-catenin signaling pathway and EMT in non-small cell lung cancer

(2017) Shucai Yang et al.   Molecular Cancer

LRG1 promotes proliferation and inhibits apoptosis in colorectal cancer cells via RUNX1 activation

(2017) Ying Zhou et al.   PLoS One

Curcumin reversed chronic tobacco smoke exposure induced urocystic EMT and acquisition of cancer stem cells properties via Wnt/β-catenin

(2017) Zhaofeng Liang et al.   Cell Death & Disease

RUNX1 contributes to higher-order chromatin organization and gene regulation in breast cancer cells

(2016) A. Rasim Barutcu et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Epigenetic silencing of miR-490-3p promotes development of an aggressive colorectal cancer phenotype through activation of the Wnt/β-catenin signaling pathway

(2016) Kehong Zheng et al.   CANCER LETTERS

Alternative RUNX1 Promoter Regulation by Wnt/β-Catenin Signaling in Leukemia Cells and Human Hematopoietic Progenitors

(2016) Matías A. Medina et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Gab2 facilitates epithelial-to-mesenchymal transition via the MEK/ERK/MMP signaling in colorectal cancer

(2016) Chenbo Ding et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

TUSC3 promotes colorectal cancer progression and epithelial-mesenchymal transition (EMT) through WNT/β-catenin and MAPK signalling

(2016) Ye Gu et al.   JOURNAL OF PATHOLOGY

Long Noncoding RNA H19-Derived miR-675 Enhances Proliferation and Invasion via RUNX1 in Gastric Cancer Cells

(2016) Gao Liu et al.   ONCOLOGY RESEARCH

RUNX1 prevents oestrogen-mediated AXIN1 suppression and β-catenin activation in ER-positive breast cancer

(2016) Nyam-Osor Chimge et al.   Nature Communications

Systems Pharmacogenomics Finds RUNX1 Is an Aspirin-Responsive Transcription Factor Linked to Cardiovascular Disease and Colon Cancer

(2016) Deepak Voora et al.   EBioMedicine

Wnt signaling induces transcription, spatial proximity, and translocation of fusion gene partners in human hematopoietic cells

(2015) G. D. Ugarte et al.   BLOOD

Identification of the genes regulated by Wnt-4, a critical signal for commitment of the ovary

(2015) Florence Naillat et al.   EXPERIMENTAL CELL RESEARCH

KIT Signaling Promotes Growth of Colon Xenograft Tumors in Mice and Is Up-Regulated in a Subset of Human Colon Cancers

(2015) Evan C. Chen et al.   GASTROENTEROLOGY

New Wnt/β-catenin target genes promote experimental metastasis and migration of colorectal cancer cells through different signals

(2015) Jingjing Qi et al.   GUT

The long non-coding RNA H19-derived miR-675 modulates human gastric cancer cell proliferation by targeting tumor suppressor RUNX1

(2014) Ming Zhuang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

LincRNA-uc002yug.2 involves in alternative splicing of RUNX1 and serves as a predictor for esophageal cancer and prognosis

(2014) H Wu et al.   ONCOGENE

Signaling mechanisms of the epithelial-mesenchymal transition

(2014) D. M. Gonzalez et al.   Science Signaling

The RUNX1 transcription factor is expressed in serous epithelial ovarian carcinoma and contributes to cell proliferation, migration and invasion

(2013) Mamadou Keita et al.   CELL CYCLE

CTCF mediates theTERTenhancer-promoter interactions in lung cancer cells: Identification of a novel enhancer region involved in the regulation ofTERTgene

(2013) Vegard Eldholm et al.   INTERNATIONAL JOURNAL OF CANCER

Defining a tissue stem cell-driven Runx1/Stat3 signalling axis in epithelial cancer

(2012) Cornelia Johanna Franziska Scheitz et al.   EMBO JOURNAL

c-Kit mediates chemoresistance and tumor-initiating capacity of ovarian cancer cells through activation of Wnt/β-catenin–ATP-binding cassette G2 signaling

(2012) W K Chau et al.   ONCOGENE

Stromelysin-1 (MMP-3) is a target and a regulator of Wnt1-induced epithelial-mesenchymal transition (EMT)

(2010) Laurence Blavier et al.   CANCER BIOLOGY & THERAPY

Associations between genetic variation in RUNX1 , RUNX2 , RUNX3 , MAPK1 and eIF4E and risk of colon and rectal cancer: additional support for a TGF-β-signaling pathway

(2010) Martha L. Slattery et al.   CARCINOGENESIS