Ivermectin reverses the drug resistance in cancer cells through EGFR/ERK/Akt/NF-κB pathway

Metabolomics in breast cancer: A decade in review

(2018) Amelia McCartney et al.   CANCER TREATMENT REVIEWS

Towards Comprehension of the ABCB1/P-Glycoprotein Role in Chronic Myeloid Leukemia

(2018) Raquel Maia et al.   MOLECULES

Dominance of P-glycoprotein 12 in phenotypic resistance conversion against ivermectin in Caenorhabditis elegans

(2018) Luiza Almeida Figueiredo et al.   PLoS One

Promising approach to reducing Malaria transmission by ivermectin: Sporontocidal effect against Plasmodium vivax in the South American vectors Anopheles aquasalis and Anopheles darlingi

(2018) Yudi T. Pinilla et al.   PLoS Neglected Tropical Diseases

Molecular Determinants of Sensitivity or Resistance of Cancer Cells Toward Sanguinarine

(2018) Mohamed E. M. Saeed et al.   Frontiers in Pharmacology

Drug resistance in multiple myeloma

(2018) Pawel Robak et al.   CANCER TREATMENT REVIEWS

Macrocyclic lactones inhibit nasopharyngeal carcinoma cells proliferation through PAK1 inhibition and reduce in vivo tumor growth

(2018) Franck Gallardo et al.   Drug Design Development and Therapy

Targeting the Multidrug Transporter Ptch1 Potentiates Chemotherapy Efficiency

(2018) Anida Hasanovic et al.   Cells

The Effects of Synthetically Modified Natural Compounds on ABC Transporters

(2018) Daniel Dantzic et al.   Pharmaceutics

A Trial of a Triple-Drug Treatment for Lymphatic Filariasis

(2018) Christopher L. King et al.   NEW ENGLAND JOURNAL OF MEDICINE

Overcoming ABC transporter-mediated multidrug resistance: The dual role of tyrosine kinase inhibitors as multitargeting agents

(2017) Giovanni Luca Beretta et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Natural alkaloids as P-gp inhibitors for multidrug resistance reversal in cancer

(2017) Prashant Joshi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

In vivo loss-of-function screens identify KPNB1 as a new druggable oncogene in epithelial ovarian cancer

(2017) Michiko Kodama et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

P-glycoproteins play a role in ivermectin resistance in cyathostomins

(2017) L.E. Peachey et al.   International Journal for Parasitology-Drugs and Drug Resistance

Ivermectin Induces Cytostatic Autophagy by Blocking the PAK1/Akt Axis in Breast Cancer

(2016) Q. Dou et al.   CANCER RESEARCH

LRIG1, human EGFR inhibitor, reverses multidrug resistance through modulation of ABCB1 and ABCG2

(2015) Baohui Liu et al.   BRAIN RESEARCH

Modulation of P2X4/P2X7/Pannexin-1 sensitivity to extracellular ATP via Ivermectin induces a non-apoptotic and inflammatory form of cancer cell death

(2015) Dobrin Draganov et al.   Scientific Reports

Mass Administration of Ivermectin for the Elimination of Onchocerciasis Significantly Reduced and Maintained Low the Prevalence of Strongyloides stercoralis in Esmeraldas, Ecuador

(2015) Mariella Anselmi et al.   PLoS Neglected Tropical Diseases

Chronic myeloid leukemia: 2014 update on diagnosis, monitoring, and management

(2014) Elias Jabbour et al.   AMERICAN JOURNAL OF HEMATOLOGY

EGFR mediates docetaxel resistance in human castration-resistant prostate cancer through the Akt-dependent expression of ABCB1 (MDR1)

(2014) Tzyh-Chyuan Hour et al.   ARCHIVES OF TOXICOLOGY

The river blindness drug Ivermectin and related macrocyclic lactones inhibit WNT-TCF pathway responses in human cancer

(2014) A. Melotti et al.   EMBO Molecular Medicine

Ivermectin exposure leads to up-regulation of detoxification genes in vitro and in vivo in mice

(2014) Mélanie Albérich et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Nrf2 Upregulates ATP Binding Cassette Transporter Expression and Activity at the Blood-Brain and Blood-Spinal Cord Barriers

(2014) X. Wang et al.   JOURNAL OF NEUROSCIENCE

Sorcin, a Calcium Binding Protein Involved in the Multidrug Resistance Mechanisms in Cancer Cells

(2014) Gianni Colotti et al.   MOLECULES

Molecular aspects of cancer cell resistance to chemotherapy

(2013) Magali Rebucci et al.   BIOCHEMICAL PHARMACOLOGY

Three Decades of P-gp Inhibitors: Skimming Through Several Generations and Scaffolds

(2012) A. Palmeira et al.   CURRENT MEDICINAL CHEMISTRY

Ivermectin induces P-glycoprotein expression and function through mRNA stabilization in murine hepatocyte cell line

(2011) Cécile Ménez et al.   BIOCHEMICAL PHARMACOLOGY

The antiparasitic agent ivermectin induces chloride-dependent membrane hyperpolarization and cell death in leukemia cells

(2010) S. Sharmeen et al.   BLOOD

PSC833, cyclosporine analogue, downregulates MDR1 expression by activating JNK/c-Jun/AP-1 and suppressing NF-κB

(2009) H. Bark et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Effects of avermectins on neurite outgrowth in differentiating mouse neuroblastoma N2a cells

(2009) Ying-Jian Sun et al.   TOXICOLOGY LETTERS

Lapatinib (Tykerb, GW572016) Reverses Multidrug Resistance in Cancer Cells by Inhibiting the Activity of ATP-Binding Cassette Subfamily B Member 1 and G Member 2

(2008) C.-l. Dai et al.   CANCER RESEARCH