Identification of Gli1‐interacting proteins during simvastatin‐stimulated osteogenic differentiation of bone marrow mesenchymal stem cells

Non-genomic mechanisms of protein phosphatase 2A (PP2A) regulation in cancer

(2018) Otto Kauko et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Oestrogen receptor α regulates the odonto/osteogenic differentiation of stem cells from apical papilla via ERK and JNK MAPK pathways

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Suppressor of Fused restraint of Hedgehog activity level is critical for osteogenic proliferation and differentiation during calvarial bone development

(2017) Jianying Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

β1 integrin–dependent Rac/group I PAK signaling mediates YAP activation of Yes-associated protein 1 (YAP1) via NF2/merlin

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Fibroblast contributes for osteoblastic phenotype in a MAPK-ERK and sonic hedgehog signaling-independent manner

(2017) Celio J. da Costa Fernandes et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Gli1 identifies osteogenic progenitors for bone formation and fracture repair

(2017) Yu Shi et al.   Nature Communications

Regulation of Calvarial Osteogenesis by Concomitant De-repression of GLI3 and Activation of IHH Targets

(2017) Lotta K. Veistinen et al.   Frontiers in Physiology

Simvastatin-Induced Apoptosis in Osteosarcoma Cells: A Key Role of RhoA-AMPK/p38 MAPK Signaling in Antitumor Activity

(2016) Walied A. Kamel et al.   MOLECULAR CANCER THERAPEUTICS

PSMC2 is up-regulated in osteosarcoma and regulates osteosarcoma cell proliferation, apoptosis and migration

(2016) Mingzhi Song et al.   Oncotarget

Irisin promotes osteoblast proliferation and differentiation via activating the MAP kinase signaling pathways

(2016) Xiaoyong Qiao et al.   Scientific Reports

Characterization and Expression of Senescence Marker in Prolonged Passages of Rat Bone Marrow-Derived Mesenchymal Stem Cells

(2016) Noridzzaida Ridzuan et al.   Stem Cells International

Exendin-4 promotes endothelial barrier enhancement via PKA- and Epac1-dependent Rac1 activation

(2015) Ai Q. Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Role for RalA downstream of Rac1 in skeletal muscle insulin signalling

(2015) Nobuyuki Takenaka et al.   BIOCHEMICAL JOURNAL

Estrogen receptor mediates simvastatin-stimulated osteogenic effects in bone marrow mesenchymal stem cells

(2015) Shu-Chun Chuang et al.   BIOCHEMICAL PHARMACOLOGY

Geometry sensing through POR1 regulates Rac1 activity controlling early osteoblast differentiation in response to nanofiber diameter

(2015) A. M. Higgins et al.   Integrative Biology

Deletion of Rac in Mature Osteoclasts Causes Osteopetrosis, an Age-Dependent Change in Osteoclast Number, and a Reduced Number of Osteoblasts In Vivo

(2015) Meiling Zhu et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Osteoporosis-associated alteration in the signalling status of BMP-2 in human MSCs under adipogenic conditions

(2015) Oscar Donoso et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Exendin-4 promotes proliferation and differentiation of MC3T3-E1 osteoblasts by MAPKs activation

(2015) Yingyu Feng et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Rac limits TGF-β-induced VEGF synthesis in osteoblasts

(2015) Naohiro Yamamoto et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Hedgehog signaling activates a positive feedback mechanism involving insulin-like growth factors to induce osteoblast differentiation

(2015) Yu Shi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitogen-activated protein kinases and Hedgehog-GLI signaling in cancer: A crosstalk providing therapeutic opportunities?

(2015) Elisabetta Rovida et al.   SEMINARS IN CANCER BIOLOGY

Effects of simvastatin on the osteogenic differentiation and immunomodulation of bone marrow mesenchymal stem cells

(2015) JIANYI NIU et al.   Molecular Medicine Reports

Simvastatin Modulates Mesenchymal Stromal Cell Proliferation and Gene Expression

(2015) Dalila Lucíola Zanette et al.   PLoS One

Extracellular Matrix Stiffness Regulates Osteogenic Differentiation through MAPK Activation

(2015) Jun-Ha Hwang et al.   PLoS One

Simvastatin coating of TiO2 scaffold induces osteogenic differentiation of human adipose tissue-derived mesenchymal stem cells

(2014) Helen Pullisaar et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Novel Hedgehog Agonists Promote Osteoblast Differentiation in Mesenchymal Stem Cells

(2014) Takashi Nakamura et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The isolation and cultivation of bone marrow stem cells and evaluation of differences for neural-like cells differentiation under the induction with neurotrophic factors

(2013) Jian-Dong Yang et al.   CYTOTECHNOLOGY

Contribution of genetic and epigenetic mechanisms to Wnt pathway activity in prevalent skeletal disorders

(2013) Carmen García-Ibarbia et al.   GENE

The mechanisms of Hedgehog signalling and its roles in development and disease

(2013) James Briscoe et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

In Vitro Study of a Novel Oxysterol for Osteogenic Differentiation on Rabbit Bone Marrow Stromal Cells

(2013) Akishige Hokugo et al.   PLASTIC AND RECONSTRUCTIVE SURGERY

Ihh and Runx2/Runx3 Signaling Interact to Coordinate Early Chondrogenesis: A Mouse Model

(2013) Eun-Jung Kim et al.   PLoS One

Additive Effects of Sonic Hedgehog and Nell-1 Signaling in Osteogenic Versus Adipogenic Differentiation of Human Adipose-Derived Stromal Cells

(2012) Aaron W. James et al.   STEM CELLS AND DEVELOPMENT

Glucagon Like Peptide-1-Directed Human Embryonic Stem Cells Differentiation Into Insulin-Producing Cells Via Hedgehog, cAMP, and PI3K Pathways

(2010) Hongxiang Hui et al.   PANCREAS

Fibroblast growth factor 2-induced cytoplasmic asparaginyl-tRNA synthetase promotes survival of osteoblasts by regulating anti-apoptotic PI3K/Akt signaling

(2009) Su Jin Park et al.   BONE

Hedgehog: functions and mechanisms

(2008) M. Varjosalo et al.   GENES & DEVELOPMENT