NMR characterization of solvent accessibility and transient structure in intrinsically disordered proteins

Regulation of cellular senescence via the FOXO4-p53 axis

(2018) Benjamin Bourgeois et al.   FEBS LETTERS

Re-evaluating the role of FOXOs in cancer

(2018) M. Hornsveld et al.   SEMINARS IN CANCER BIOLOGY

Local and Global Dynamics in Intrinsically Disordered Synuclein

(2018) Nasrollah Rezaei-Ghaleh et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Conformational Ensemble of Disordered Proteins Probed by Solvent Paramagnetic Relaxation Enhancement (sPRE)

(2018) Hamed Kooshapur et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Measuring Solvent Hydrogen Exchange Rates by Multifrequency Excitation 15N CEST: Application to Protein Phase Separation

(2018) Tairan Yuwen et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Realistic Ensemble Models of Intrinsically Disordered Proteins Using a Structure-Encoding Coil Database

(2018) Alejandro Estaña et al.   STRUCTURE

Flexible IgE epitope-containing domains of Phl p 5 cause high allergenic activity

(2017) Christoph Göbl et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Structural and hydrodynamic properties of an intrinsically disordered region of a germ cell-specific protein on phase separation

(2017) Jacob P. Brady et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Allosteric modulation of peroxisomal membrane protein recognition by farnesylation of the peroxisomal import receptor PEX19

(2017) Leonidas Emmanouilidis et al.   Nature Communications

RNA structure refinement using NMR solvent accessibility data

(2017) Christoph Hartlmüller et al.   Scientific Reports

Prediction of Protein Structure Using Surface Accessibility Data

(2016) Christoph Hartlmüller et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Protein Structural Ensembles Visualized by Solvent Paramagnetic Relaxation Enhancement

(2016) Zhou Gong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Increasing the Chemical-Shift Dispersion of Unstructured Proteins with a Covalent Lanthanide Shift Reagent

(2016) Christoph Göbl et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Modulation of Intrinsically Disordered Protein Function by Post-translational Modifications

(2016) Alaji Bah et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CcpNmr AnalysisAssign: a flexible platform for integrated NMR analysis

(2016) Simon P. Skinner et al.   JOURNAL OF BIOMOLECULAR NMR

The Transactivation Domains of the p53 Protein

(2016) Nitin Raj et al.   Cold Spring Harbor Perspectives in Medicine

Intrinsically disordered proteins in cellular signalling and regulation

(2015) Peter E. Wright et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Pathological Unfoldomics of Uncontrolled Chaos: Intrinsically Disordered Proteins and Human Diseases

(2014) Vladimir N. Uversky et al.   CHEMICAL REVIEWS

Exploring Free-Energy Landscapes of Intrinsically Disordered Proteins at Atomic Resolution Using NMR Spectroscopy

(2014) Malene Ringkjøbing Jensen et al.   CHEMICAL REVIEWS

Physicochemical Properties of Cells and Their Effects on Intrinsically Disordered Proteins (IDPs)

(2014) Francois-Xavier Theillet et al.   CHEMICAL REVIEWS

Introducing Protein Intrinsic Disorder

(2014) Johnny Habchi et al.   CHEMICAL REVIEWS

Classification of Intrinsically Disordered Regions and Proteins

(2014) Robin van der Lee et al.   CHEMICAL REVIEWS

Controlling entropy to tune the functions of intrinsically disordered regions

(2014) Tilman Flock et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

A decadentate Gd(III)-coordinating paramagnetic cosolvent for protein relaxation enhancement measurement

(2014) Xin-Hua Gu et al.   JOURNAL OF BIOMOLECULAR NMR

Perspectives in magnetic resonance: NMR in the post-FFT era

(2014) Sven G. Hyberts et al.   JOURNAL OF MAGNETIC RESONANCE

Transient Electrostatic Interactions Dominate the Conformational Equilibrium Sampled by Multidomain Splicing Factor U2AF65: A Combined NMR and SAXS Study

(2014) Jie-rong Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Long-Range Correlated Dynamics in Intrinsically Disordered Proteins

(2014) Giacomo Parigi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Specific and Nonspecific Interactions in Ultraweak Protein–Protein Associations Revealed by Solvent Paramagnetic Relaxation Enhancements

(2014) Helle Johansson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

NMR approaches for structural analysis of multidomain proteins and complexes in solution

(2014) Christoph Göbl et al.   PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

Studying the Structure and Dynamics of Biomolecules by Using Soluble Paramagnetic Probes

(2013) Henry G. Hocking et al.   CHEMPHYSCHEM

Structure determination of protein–protein complexes with long-range anisotropic paramagnetic NMR restraints

(2013) Mathias AS Hass et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

The Small GTPase RALA Controls c-Jun N-terminal Kinase-mediated FOXO Activation by Regulation of a JIP1 Scaffold Complex

(2013) Maaike C. W. van den Berg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Redox-Dependent Control of FOXO/DAF-16 by Transportin-1

(2013) Marrit Putker et al.   MOLECULAR CELL

Direct Prediction of NMR Residual Dipolar Couplings from the Primary Sequence of Unfolded Proteins

(2012) Jie-rong Huang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Regulation of protein phosphatase 1 by intrinsically disordered proteins

(2012) Meng S. Choy et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Flexible-meccano: a tool for the generation of explicit ensemble descriptions of intrinsically disordered proteins and their associated experimental observables

(2012) V. Ozenne et al.   BIOINFORMATICS

Competitive Binding between Dynamic p53 Transactivation Subdomains to Human MDM2 Protein

(2012) Bing Shan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Parameterization of solvent–protein interaction and its use on NMR protein structure determination

(2012) Yu Wang et al.   JOURNAL OF MAGNETIC RESONANCE

HMGB1-Facilitated p53 DNA Binding Occurs via HMG-Box/p53 Transactivation Domain Interaction, Regulated by the Acidic Tail

(2012) John P. Rowell et al.   STRUCTURE

Intrinsically disordered proteins: a 10-year recap

(2012) Peter Tompa   TRENDS IN BIOCHEMICAL SCIENCES

Structural Analysis of Large Protein Complexes Using Solvent Paramagnetic Relaxation Enhancements

(2011) Tobias Madl et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cosolute Paramagnetic Relaxation Enhancements Detect Transient Conformations of Human Uracil DNA Glycosylase (hUNG)

(2011) Yan Sun et al.   BIOCHEMISTRY

The neurotransmitter serotonin interrupts α-synuclein amyloid maturation

(2011) S. Fabio Falsone et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Intrinsically disordered proteins: regulation and disease

(2011) M Madan Babu et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Intrinsically disordered proteins from A to Z

(2011) Vladimir N. Uversky   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Protein NMR Using Paramagnetic Ions

(2010) Gottfried Otting   Annual Review of Biophysics

Solution Structure and Membrane Binding of the Toxin Fst of theparAddiction Module

(2010) Christoph Göbl et al.   BIOCHEMISTRY

Activation of Forkhead Box O Transcription Factors by Oncogenic BRAF Promotes p21cip1-Dependent Senescence

(2010) P. L. J. de Keizer et al.   CANCER RESEARCH

Intrinsically disordered proteins are potential drug targets

(2010) Steven J Metallo   CURRENT OPINION IN CHEMICAL BIOLOGY

Structure-Independent Analysis of the Breadth of the Positional Distribution of Disordered Groups in Macromolecules from Order Parameters for Long, Variable-Length Vectors Using NMR Paramagnetic Relaxation Enhancement

(2010) Junji Iwahara et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

NMR Characterization of Long-Range Order in Intrinsically Disordered Proteins

(2010) Loïc Salmon et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1

(2010) Thomas Güttler et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The relevance of protein-protein interactions for p53 function: the CPE contribution

(2010) M. R. Fernandez-Fernandez et al.   PROTEIN ENGINEERING DESIGN & SELECTION

 -Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro

(2010) J. Burre et al.   SCIENCE

Use of Relaxation Enhancements in a Paramagnetic Environment for the Structure Determination of Proteins Using NMR Spectroscopy

(2009) Tobias Madl et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Two Distinct Motifs within the p53 Transactivation Domain Bind to the Taz2 Domain of p300 and Are Differentially Affected by Phosphorylation†

(2009) Lisa M. Miller Jenkins et al.   BIOCHEMISTRY

Blinded by the Light: The Growing Complexity of p53

(2009) Karen H. Vousden et al.   CELL

Theory, Practice, and Applications of Paramagnetic Relaxation Enhancement for the Characterization of Transient Low-Population States of Biological Macromolecules and Their Complexes

(2009) G. Marius Clore et al.   CHEMICAL REVIEWS

Biophysical characterization of intrinsically disordered proteins

(2009) David Eliezer   CURRENT OPINION IN STRUCTURAL BIOLOGY

Linking folding and binding

(2009) Peter E Wright et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Positioning of Micelle-Bound Peptides by Paramagnetic Relaxation Enhancements

(2009) Klaus Zangger et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Quantitative Description of Backbone Conformational Sampling of Unfolded Proteins at Amino Acid Resolution from NMR Residual Dipolar Couplings

(2009) Gabrielle Nodet et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Functional Amyloids As Natural Storage of Peptide Hormones in Pituitary Secretory Granules

(2009) S. K. Maji et al.   SCIENCE

Quantitative Determination of the Conformational Properties of Partially Folded and Intrinsically Disordered Proteins Using NMR Dipolar Couplings

(2009) Malene Ringkjøbing Jensen et al.   STRUCTURE

TP53 Mutations in Human Cancers: Origins, Consequences, and Clinical Use

(2009) M. Olivier et al.   Cold Spring Harbor Perspectives in Biology

Intrinsically Disordered Proteins in Human Diseases: Introducing the D2 Concept

(2008) Vladimir N. Uversky et al.   Annual Review of Biophysics

Conformational distributions of unfolded polypeptides from novel NMR techniques

(2008) Sebastian Meier et al.   JOURNAL OF CHEMICAL PHYSICS

Calculation of Residual Dipolar Couplings from Disordered State Ensembles Using Local Alignment

(2008) Joseph A. Marsh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structure of tumor suppressor p53 and its intrinsically disordered N-terminal transactivation domain

(2008) M. Wells et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Probing protein surface accessibility with solvent and paramagnetic molecules

(2008) Andrea Bernini et al.   PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY