Trophoblast cell surface antigen 2 (Trop-2) phosphorylation by protein kinase C α/δ (PKCα/δ) enhances cell motility

High expression of TROP2 characterizes different cell subpopulations in androgen-sensitive and androgen-independent prostate cancer cells

(2016) Jinhan Xie et al.   Oncotarget

Impact of TROP2 expression on prognosis in solid tumors: A Systematic Review and Meta-analysis

(2016) Ping Zeng et al.   Scientific Reports

MUC1 Protein Induces Urokinase-type Plasminogen Activator (uPA) by Forming a Complex with NF-κB p65 Transcription Factor and Binding to the uPA Promoter, Leading to Enhanced Invasiveness of Cancer Cells

(2014) Yugo Mori et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ultradeep Human Phosphoproteome Reveals a Distinct Regulatory Nature of Tyr and Ser/Thr-Based Signaling

(2014) Kirti Sharma et al.   Cell Reports

Trop-2 Promotes Prostate Cancer Metastasis By Modulating  1 Integrin Functions

(2013) M. Trerotola et al.   CANCER RESEARCH

Protein kinase Cα inhibitor protects against downregulation of claudin-1 during epithelial–mesenchymal transition of pancreatic cancer

(2013) Daisuke Kyuno et al.   CARCINOGENESIS

CA125/MUC16 interacts with Src family kinases, and over-expression of its C-terminal fragment in human epithelial cancer cells reduces cell–cell adhesion

(2013) Kaoru Akita et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Protein Kinase D Promotes Airway Epithelial Barrier Dysfunction and Permeability through Down-regulation of Claudin-1

(2013) Huachen Gan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epithelial Cell Adhesion Molecule (EpCAM) Regulates Claudin Dynamics and Tight Junctions

(2013) Chuan-Jin Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Claudins and the Modulation of Tight Junction Permeability

(2013) Dorothee Günzel et al.   PHYSIOLOGICAL REVIEWS

EpCAM contributes to formation of functional tight junction in the intestinal epithelium by recruiting claudin proteins

(2012) Zili Lei et al.   DEVELOPMENTAL BIOLOGY

Regulated proteolysis of Trop2 drives epithelial hyperplasia and stem cell self-renewal via  -catenin signaling

(2012) T. Stoyanova et al.   GENES & DEVELOPMENT

Upregulation of Trop-2 quantitatively stimulates human cancer growth

(2012) M Trerotola et al.   ONCOGENE

Cardiac Actions of Protein Kinase C Isoforms

(2012) Susan F. Steinberg   PHYSIOLOGY

The level of claudin-7 is reduced as an early event in colorectal carcinogenesis

(2011) Jette Bornholdt et al.   BMC CANCER

Protein kinase D: coupling extracellular stimuli to the regulation of cell physiology

(2011) Ya Fu et al.   EMBO REPORTS

Claudin-7 inhibits human lung cancer cell migration and invasion through ERK/MAPK signaling pathway

(2011) Zhe Lu et al.   EXPERIMENTAL CELL RESEARCH

Inflammation and Disruption of the Mucosal Architecture in Claudin-7–Deficient Mice

(2011) Lei Ding et al.   GASTROENTEROLOGY

Loss of Trop2 Promotes Carcinogenesis and Features of Epithelial to Mesenchymal Transition in Squamous Cell Carcinoma

(2011) J. Wang et al.   MOLECULAR CANCER RESEARCH

Tumor-Associated Calcium Signal Transducer 2 Is Required for the Proper Subcellular Localization of Claudin 1 and 7

(2010) Mina Nakatsukasa et al.   AMERICAN JOURNAL OF PATHOLOGY

Trop-2 overexpression as an independent marker for poor overall survival in ovarian carcinoma patients

(2010) Eliana Bignotti et al.   EUROPEAN JOURNAL OF CANCER

Trop2: A possible therapeutic target for late stage epithelial carcinomas

(2009) Rafael Cubas et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Identification of Trop-2 as an oncogene and an attractive therapeutic target in colon cancers

(2008) J. Wang et al.   MOLECULAR CANCER THERAPEUTICS