Upregulation of Trop-2 quantitatively stimulates human cancer growth

Uterine serous papillary carcinomas overexpress human trophoblast-cell-surface marker (trop-2) and are highly sensitive to immunotherapy with hRS7, a humanized anti-trop-2 monoclonal antibody

(2011) Joyce Varughese et al.   CANCER

Loss of Trop2 Promotes Carcinogenesis and Features of Epithelial to Mesenchymal Transition in Squamous Cell Carcinoma

(2011) J. Wang et al.   MOLECULAR CANCER RESEARCH

Trop-2 overexpression as an independent marker for poor overall survival in ovarian carcinoma patients

(2010) Eliana Bignotti et al.   EUROPEAN JOURNAL OF CANCER

Trop2 expression contributes to tumor pathogenesis by activating the ERK MAPK pathway

(2010) Rafael Cubas et al.   Molecular Cancer

Primitive origins of prostate cancer: In vivo evidence for prostate-regenerating cells and prostate cancer-initiating cells

(2010) Andrew S. Goldstein et al.   Molecular Oncology

The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models

(2010)   NATURE BIOTECHNOLOGY

Elevated expressions of MMP7, TROP2, and survivin are associated with survival, disease recurrence, and liver metastasis of colon cancer

(2009) Y. J. Fang et al.   INTERNATIONAL JOURNAL OF COLORECTAL DISEASE

Nuclear signalling by tumour-associated antigen EpCAM

(2009) Dorothea Maetzel et al.   NATURE CELL BIOLOGY

High expression of TROP2 correlates with poor prognosis in pancreatic cancer

(2008) D Fong et al.   BRITISH JOURNAL OF CANCER

A Bicistronic CYCLIN D1-TROP2 mRNA Chimera Demonstrates a Novel Oncogenic Mechanism in Human Cancer

(2008) E. Guerra et al.   CANCER RESEARCH

Intestinal tumour chemoprevention with the antioxidant lipoic acid stimulates the growth of breast cancer

(2008) Cosmo Rossi et al.   EUROPEAN JOURNAL OF CANCER

TROP2 expression as prognostic marker for gastric carcinoma

(2008) G Muhlmann et al.   JOURNAL OF CLINICAL PATHOLOGY

Identification of Trop-2 as an oncogene and an attractive therapeutic target in colon cancers

(2008) J. Wang et al.   MOLECULAR CANCER THERAPEUTICS